A5025705777- RNA modifications and cancer
- Bacterial Infections and Vaccines
- Ferroptosis and cancer prognosis
- Air Quality and Health Impacts
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Gut microbiota and health
- Cancer Immunotherapy and Biomarkers
- Wnt/β-catenin signaling in development and cancer
- Cancer Genomics and Diagnostics
- Clostridium difficile and Clostridium perfringens research
- Meningioma and schwannoma management
- Pluripotent Stem Cells Research
- Virus-based gene therapy research
- Pharmacovigilance and Adverse Drug Reactions
- Adipose Tissue and Metabolism
- Renal and related cancers
- Cancer-related gene regulation
- Health, Environment, Cognitive Aging
- Biomedical Ethics and Regulation
- Respiratory viral infections research
- Single-cell and spatial transcriptomics
- Climate Change and Health Impacts
- Cancer Research and Treatments
- Management of metastatic bone disease
Central South University
2021-2024
Xiangya Hospital Central South University
2021-2024
Southern Medical University
2024
Chongqing Medical University
2024
Zhujiang Hospital
2024
Dalian Medical University
2024
Second Affiliated Hospital of Chongqing Medical University
2024
Abstract Aims The dysregulation of TGF‐β signaling is a crucial pathophysiological process in tumorigenesis and progression. LncRNAs have diverse biological functions are significant participants the regulation tumor pathways. However, clinical value lncRNAs related to glioma currently unclear. Methods Data on glioma's RNA‐seq transcriptome, somatic mutation, DNA methylation data, clinicopathological information were derived from CGGA TCGA databases. A prognostic lncRNA signature was...
Abstract Background The burden of elderly cardiovascular disease (CVD) has received increasing attention with population ageing worldwide. Aims We reported on the global CVD in individuals over 70, 1990–2019. Methods and results Based Global Burden Disease Study 2019, data were analysed. Temporal trends analysed joinpoint model. slope index concentration used to evaluate health inequality. From 1990 incidence, prevalence, death, disability-adjusted life year rates generally decreased....
Stroke attributable to nonoptimal temperature needs more attention with dramatic climate change. The aim of this study was estimate the global burden and distribution characteristics burden.
Meningitis is a severe and fatal neurological disease causes lots of burden. The purpose this study was to assess the global, regional, national burdens trends meningitis by age, sex, etiology.
Abstract Regenerative medicine mainly relies on heterologous transplantation, often hindered by sample availability and ethical issues. Furthermore, patients are required to take immunosuppressive medications prevent adverse side effects. Stem cell-derived 3D-organoid culture has provided new alternatives for transplantation regenerative medicine. Scholars have combined organoids with tissue engineering technology improve reproducibility, the accuracy of constitution throughput, genetic...
Myasthenia gravis (MG) is a complex autoimmune disease affecting the neuromuscular junction with limited drug options, but field of MG treatment recently benefits from novel biological agents. We performed drug-targeted Mendelian randomization (MR) study to identify therapeutic targets MG. Cis-expression quantitative loci (cis-eQTL), which proxy expression levels for 2176 druggable genes, were used MR analysis. Causal relationships between genes and disease, identified by eQTL analysis,...
Introduction Cardiopulmonary complications and cognitive impairment following craniotomy have a significantly impact on the general health of individuals with brain tumours. Observational research indicates that engaging in walking is linked to better prognosis patient after surgery. This trial aims explore whether exercise prior tumour patients can reduce incidence cardiopulmonary preserve patients’ function. Methods analysis In this randomised controlled trial, 160 participants...
This paper studies the characteristics and roles in tumor microenvironment, details causes of generation development, briefly describes types functions immune cells immunometabolism-related diseases, points out relationship between microenvironment dual role provides theoretical to inhibit proliferation thus development tumors.