- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- MXene and MAX Phase Materials
- Lung Cancer Diagnosis and Treatment
- Machine Learning in Materials Science
- Pediatric Urology and Nephrology Studies
- ZnO doping and properties
- Chalcogenide Semiconductor Thin Films
- Semiconductor materials and interfaces
- Medical Image Segmentation Techniques
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Fetal and Pediatric Neurological Disorders
- Signaling Pathways in Disease
- Chronic Lymphocytic Leukemia Research
- Inorganic Chemistry and Materials
- Renal and Vascular Pathologies
- Intuitionistic Fuzzy Systems Applications
- Vascular Procedures and Complications
- Economic and Technological Systems Analysis
- Colorectal Cancer Screening and Detection
- Nanowire Synthesis and Applications
- Evolutionary Algorithms and Applications
- Central Venous Catheters and Hemodialysis
Uttaranchal University
2024
University of Kota
2016-2023
Hofstra University
2015
New York University
2004-2012
NYU Langone Health
2011
Resonance Research (United States)
2004
Columbia University Irving Medical Center
2004
GTx (United States)
2004
Yonsei University
2002
Cornell University
2002
Background — Compared with younger patients, myocardial infarction in the elderly has been associated less favorable clinical outcomes, which may be attributable to a decline angiogenic capacity aging heart. Methods and Results To test hypothesis that functional phenotype of cardiac microvascular endothelial cells is maintained partly by myocyte platelet-derived growth factor (PDGF)-B–induced paracrine pathway, we conducted vitro studies murine cells. These demonstrated unlike young cells,...
The purpose of this study was to determine the accuracy and sources error in estimating single-kidney glomerular filtration rate (GFR) derived from low-dose gadolinium-enhanced T1-weighted MR renography. To analyze imaging data, signal intensity curves were converted concentration vs. time curves, a three-compartment, six-parameter model vascular-nephron system used measured aortic, cortical, medullary enhancement curves. Reliability parameter estimates evaluated by sensitivity analysis...
To determine the precision of a three-dimensional (3D) method for measuring growth rate solid and subsolid nodules its ability to detect abnormal rates.This study was approved by Institutional Research Board HIPAA compliant. Informed consent waived. The rates 123 lung in 59 patients who had undergone cancer screening computed tomography (CT) were measured using 3D semiautomated computer-assisted volume method. Clinical stability established with long-term CT follow-up (mean, 6.4 years±1.9...
The accuracy and precision of an automated graph-cuts (GC) segmentation technique for dynamic contrast-enhanced (DCE) 3D MR renography (MRR) was analyzed using 18 simulated 22 clinical datasets. For data, the error 7.2 +/- 6.1 cm(3) cortex 6.5 4.6 medulla. 7.1 4.2 2.4 Compartmental modeling kidney function in kidneys yielded a renal plasma flow (RPF) 7.5% 4.5% single-kidney GFR 13.5% 8.8%. 9.7% 6.4% RPF 14.8% 11.9% GFR. It took 21 min to segment one GC, compared 2.5 hr manual segmentation....
Abstract A method for calculating contrast agent concentration from MR signal intensity (SI) was developed and validated T 1 ‐weighted renography (MRR) studies. This is based on reference measurements of SI relaxation time in a Gd‐DTPA‐doped water phantom. The same form vs. dependence observed human tissues. Contrast concentrations calculated by the proposed showed no bias between 0 mM, agreed better with values derived direct than using relative method. Phantom‐based conversion used to...
Abstract Purpose To investigate whether the loss of corticomedullary differentiation (CMD) on T1‐weighted MR images due to renal insufficiency can be attributed changes in T1 values cortex, medulla, or both. Materials and Methods Study subjects included 10 patients (serum creatinine range 0.6–3.0 mg/dL) referred for suspected renovascular disease who underwent 99m Tc‐diethylene triamine pentaacetic acid (DTPA) renography determine single kidney glomerular filtration rate (SKGFR) same‐day...
Purpose: To identify, by using a chest phantom, whether vessels that contact lung nodules measuring less than 5 mm in diameter will affect nodule volume assessment. Materials and Methods: Forty synthetic (20 with ground-glass attenuation 20 solid attenuation) measured were placed into phantom either adjacent to (n = 30) or isolated from 10) vessels. Nodules imaged low-dose mAs) diagnostic (120 multi–detector row computed tomography (CT). known lie direct confirmed visual inspection....
Dynamic contrast-enhanced 4-D MR renography has the potential for broad clinical applications, but suffers from respiratory motion that limits analysis and interpretation. Since each examination yields at least over 10 - 20 serial 3-D images of abdomen, manual registration is prohibitively labor-intensive. Besides in-plane translation, out-of-plane rotation are observed in image series. In this paper, a novel robust automated technique removing translation with sub-voxel accuracy dynamic...