A5055989350- Viral Infections and Vectors
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Yersinia bacterium, plague, ectoparasites research
- SARS-CoV-2 and COVID-19 Research
- Bacteriophages and microbial interactions
- Evolution and Genetic Dynamics
- Insect and Pesticide Research
- Plant and Fungal Interactions Research
- Zoonotic diseases and public health
- COVID-19 Clinical Research Studies
- Microbial Community Ecology and Physiology
- Animal Virus Infections Studies
- Genomics and Phylogenetic Studies
- Virology and Viral Diseases
- Plant Disease Resistance and Genetics
- Viral Infections and Outbreaks Research
- Fire effects on ecosystems
- Long-Term Effects of COVID-19
- Myxozoan Parasites in Aquatic Species
Irkutsk Antiplague Research Institute of Siberia and Far East
2019-2025
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2024
Siberian Branch of the Russian Academy of Sciences
2021-2023
Limnological Institute
2021-2023
The aim of the review is to conduct a comparative analysis epidemiological situation on tick-borne viral encephalitis (TBVE) in constituent entities Russian Federation 2015–2024 and provide forecast incidence rate for 2025. According data 2015–2024, number visits medical organizations by people that suffered from tick bites remained approximately at same level averaged 491,871.2 cases per year. Siberian, Volga, Ural Federal Districts are primary importance formation rate, accounting more...
The aim of the review was to conduct a comparative analysis epidemiological situation on tick-borne encephalitis (TBE) over 2014–2023 in constituent entities Russian Federation located European and Asian parts country give forecast incidence for 2024. TBE 2023 only marginally decreased as compared peak values 2022, which leveled down ten-year trend towards reduction. Grouping according average decade made it possible classify 17 them regions low, 15 – medium, high risk. In general, regarding...
We evaluated the temporal signal and substitution rate of tick-borne encephalitis virus (TBEV) using 276 complete open reading frame (ORF) sequences with known collection dates. According to a permutation test, TBEV Siberian subtype (TBEV-S) data set has no structure cannot be applied for estimation without other subtypes. The obtained suggests that common clade (TBEV-common), including all subtypes louping-ill (LIV), is characterized by lowest (1.87 × 10-5 substitutions per site year...
Until 2020, there were only three original complete genome (CG) nucleotide sequences of Omsk hemorrhagic fever virus (OHFV) in GenBank. For this reason, the evolutionary rate and divergence time assessments reported literature based on E gene sequences, but notably without temporal signal evaluation, such that their reliability is unclear. As July 2022, 47 OHFV CG have been published, which enables testing data inferring unbiased reliable substitution values. Regression analysis TempEst...
In this paper, we revealed the genetic structure and migration history of Powassan virus (POWV) reconstructed based on 25 complete genomes available in NCBI ViPR databases (accessed June 2021). The usage data set allowed us to perform a more precise assessment evolutionary rate virus. addition, proposed simple Bayesian technique for evaluation visualization 'temporal signal dynamics' along phylogenetic tree. We showed that value POWV is 3.3 × 10-5 nucleotide substitution per site year (95%...
Sponges are unusual representatives of the animal kingdom; their viromes, as part associated community, began to be studied quite recently, and, accordingly, these studies gaining momentum. The diversity viruses in sponges is high, and they most likely play a significant role composition sponge holobiont, especially under stress conditions. objects our metagenomic study were RNA two common endemic species Baikal sponges, Lubomirskia baikalensis Baikalospongia bacillifera. As result viral...
The tick-borne flavivirus group contains at least five species that are pathogenic to humans, three of which induce encephalitis (tick-borne virus, louping-ill Powassan virus) and another two hemorrhagic fever (Omsk Kyasanur Forest disease virus). To date, the molecular mechanisms responsible for these strikingly different clinical forms not completely understood. Using a bioinformatic approach, we performed analysis each amino acid (aa) position in alignment 323 polyprotein sequences...
Abstract Japanese encephalitis virus (JEV) is a positive-strand RNA virus, that causing in humans, which highly spread East and Southeast Asia, Western Pacific countries Australia. The main vector of JEV Culex spp. (mainly C. tritaeniorhynchus ). intraspecies structure comprises five genotypes (GI-GV). In the previous studies, substitution rate age most recent common ancestor (MRCA) based on complete open reading frame (ORF) / whole genome sequences were reported, however, estimates are...
Relevance. The new coronavirus infection (COVID-19) is still a public health problem and threat to socio-economic well-being. Most studies have focused predominantly on humoral immunity, there are no data the cellular composition of blood in dynamics. Aim. To study dynamics changes depending type immunity formed (natural, hybrid, breakthrough, postvaccinal) SARS-CoV-2 virus. Materials Methods. A total 130 volunteers participated study. Immunophenotyping peripheral leukocytes using flow...
The aim of the study was to analyze genetic structure populations and patterns evolutionary variability novel coronavirus infection in Siberian Far Eastern Federal Districts. Materials methods. 1033 SARS-CoV-2 genomes from samples individuals diagnosed with COVID-19 eight entities Siberia East between December 2020 November 2021 were assessed. Sequencing performed on MinION Oxford Nanopore platform using ARTIC v.3 protocol. degree isolation estimated applying Fst criterion. Phylogenetic...
Previously, the main studies were focused on viruses that cause disease in commercial and farmed shellfish damage to food enterprises (for example, Ostreavirusostreidmalaco1, Aurivirus haliotidmalaco1 Aquabirnavirus tellinae). Advances high-throughput sequencing technologies have extended natural populations of mollusks (and other invertebrates) as unexplored niches viral diversity possible sources emerging diseases. These revealed a huge mostly previously unknown filled gaps evolutionary...
We conducted a comparative analysis of individual and cross-assemblies several metatranscriptomic data sets to study viral communities using metatranscriptomes endemic Baikal mollusks. have shown that, compared dataset assemblies, Hidden Markov Model-based cross-assembly procedure increases the number contigs (or scaffolds) per sample, virotypes identified, average length scaffolds sample. The proportion assembled reads from total in samples is higher cross-assembly. De novo cross-genomic...
Abstract The tick-borne flavivirus (TBFV) group contains at least 12 members where five of them are important pathogens humans inducing diseases with varying severity (from mild fever forms to acute encephalitis). taxonomy structure TBFV is not fully clarified present. In particular, there a number paraphyletic issues encephalitis virus (TBEV) and louping-ill (LIV). this study, we aimed apply different bioinformatic approaches analyze all available complete genome amino acid sequences...