A5003247503- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Obesity, Physical Activity, Diet
- Diabetes Treatment and Management
- Adolescent and Pediatric Healthcare
- Diabetes Management and Education
- Childhood Cancer Survivors' Quality of Life
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Eating Disorders and Behaviors
- Marriage and Sexual Relationships
- Obesity and Health Practices
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Child and Adolescent Psychosocial and Emotional Development
- Diet and metabolism studies
- Child Nutrition and Feeding Issues
- Cardiovascular Health and Disease Prevention
- Metabolism, Diabetes, and Cancer
- Bullying, Victimization, and Aggression
- Cardiovascular Function and Risk Factors
- Child and Adolescent Health
- Growth Hormone and Insulin-like Growth Factors
- Birth, Development, and Health
- Pharmacology and Obesity Treatment
- Mobile Health and mHealth Applications
Washington University in St. Louis
2019-2024
University of Florida
2010-2020
Johns Hopkins University
2017-2020
Johns Hopkins Medicine
2020
University of Colorado Anschutz Medical Campus
2017-2018
University of Oklahoma Health Sciences Center
2018
University of Florida Health
1982-2017
Johns Hopkins Hospital
2017
University of Colorado Denver
2017
Children's Hospital Colorado
2017
Abstract Cosponsoring Associations: The European Society of Endocrinology and the Pediatric Endocrine Society. This guideline was funded by Objective: To formulate clinical practice guidelines for assessment, treatment, prevention pediatric obesity. Participants: participants include an Society–appointed Task Force 6 experts, a methodologist, medical writer. Evidence: evidence-based developed using Grading Recommendations, Assessment, Development, Evaluation approach to describe strength...
We detected limited mobility of small and large joints in 92 (30 per cent) 309 patients with diabetes who were one to 28 years old. Among had for more than 4.5 (the shortest duration at which microvascular complications noted), 82 169 joint limitation. Forty-one these also complications, but only 10 the 87 without limitation complications. Life-table analysis indicated an 83 cent risk after 16 if was present, a 25 absent. Consequently, identifies population exceptionally early development...
To examine the relationship between peer victimization and child parent reports of psychosocial adjustment physical activity in a clinical sample at-risk-for-overweight overweight children adolescents.The Schwartz Peer Victimization Scale, Children's Depression Inventory-Short Form, Multidimensional Anxiety Scale for Children, Social Physique PACE+ Adolescent Physical Activity Measure, Asher Loneliness were administered to 92 adolescents (54 females) aged 8-18 years. The youth's...
We randomly assigned 46 patients (mean age, 11.7 years; range, 4.5 to 32.8) with newly diagnosed insulin-dependent diabetes mellitus within two weeks of beginning insulin receive either corticosteroids for 10 plus daily azathioprine one year or no immunosuppressive therapy. Half the 20 immunosuppressed completing one-year trial had satisfactory metabolic outcomes (hemoglobin A1c <6.8 percent; stimulated peak C peptide >0.5 nmol per liter; dose <0.4 U kilogram body weight day) as compared...
The presence of cytoplasmic islet-cell autoantibodies has been recognized as a risk factor for the development diabetes mellitus in relatives patients with insulin-dependent (IDDM), but magnitude is unknown, influence other factors, such age, sex, and race.
OBJECTIVE. Open-label studies indicate that oral dichloroacetate (DCA) may be effective in treating patients with congenital lactic acidosis. We tested this hypothesis by conducting the first double-blind, randomized, control trial of DCA disease. METHODS. Forty-three who ranged age from 0.9 to 19 years were enrolled. All had persistent or intermittent hyperlactatemia, and most severe psychomotor delay. Eleven pyruvate dehydrogenase deficiency, 25 1 more defects enzymes respiratory chain, 7...
Objectives To examine family factors as predictors of metabolic control in children with type 1 diabetes and determine whether adherence behaviors mediate this relationship. Method Participants were 109 (ages 8–18) a parent. Measures diabetes-specific functioning an interview completed. Glycosylated hemoglobin (HbA1c) was the index control. Results Family strongly associated Combined demographic information, these constructs accounted for 49% variance Age moderated relation between aspects...
<h3>Objective</h3> To assess the effectiveness of parent-only vs family-based interventions for pediatric weight management in underserved rural settings. <h3>Design</h3> A 3-arm randomized controlled clinical trial. <h3>Setting</h3> All sessions were conducted at Cooperative Extension Service offices counties. <h3>Participants</h3> Ninety-three overweight or obese children (8-14 years old) and their parent(s). <h3>Intervention</h3> Families to (1) a behavioral intervention, (2) (3)...
One hundred sixty-eight patients with childhood diabetes (6 to 19 years of age) and their parents participated in 24-hr recall interviews concerning daily management behavior. Each patient parent was interviewed independently on three separate occasions. The information obtained used construct measures 13 different adherence behaviors. Parent-patient agreement good excellent for most the Agreement influenced by patient's age, consistently high parent-child found 10- 15-year-old age group....
Objective Accurate assessment of diabetes regimen adherence behaviors in youth is a challenging endeavor and limited by paucity empirically supported measures.The purpose this research to further demonstrate the validity reliability Self-Care Inventory (SCI), parent report measure with self-care behaviors.The SCI was chosen given its ease implementation, applicability multiple regimens, dual parent/youth formats.Methods Participants were 164 type 1 parent.Measures administered at regular...
The US market for organic foods has grown from $3.5 billion in 1996 to $28.6 2010, according the Organic Trade Association. products are now sold specialty stores and conventional supermarkets. contain numerous marketing claims terms, only some of which standardized regulated. In terms health advantages, diets have been convincingly demonstrated expose consumers fewer pesticides associated with human disease. farming less environmental impact than approaches. However, current evidence does...
The psychosocial functioning of overweight youth is a growing concern. Research has shown that children report lower quality life (QOL) than their non-overweight peers. This study sought to extend the literature by examining association between peer victimization, child depressive symptoms, parent distress, and health-related QOL in youth. Mediator models are used assess effect symptoms on relationship variables QOL.The sample consisted 96 at-risk-for-overweight (mean age=12.8 years) parents...
Type 2 diabetes mellitus (T2DM) in children and adolescents is becoming an increasingly important public health concern throughout the world (1–17). Because of relatively recent recognition problem this age group, many with new onset T2DM may be misclassified as having T1DM. Conversely, population becomes heavier, overweight autoimmune misdiagnosed T2DM. often associated risk factors for cardiovascular disease that already present at time diagnosis, making normalization blood glucose levels...
Islet cell antibodies (ICA) were detected in 168 (33%) of 504 patients with insulin-dependent diabetes mellitus (IDDM). Mean age onset IDDM was 8.6 +/- 0.2 yr and mean at testing 13.4 0.3 yr. None 162 controls without (mean 21.8 0.9 yr) had ICA. Caucasian (404) a 74% frequency ICA within 3 mo diagnosis an overall 36%. These results similar to those reported from Europe. Black (100) lower frequencies (P < 0.01) thyroid 0.05). before 5 (107) (21%) than (297) later (42%). Patients persistent...
Type 2 diabetes mellitus (T2DM) in children and adolescents is becoming an increasingly important public health concern throughout the world (1–17). Because of relatively recent recognition problem this age-group, many with new-onset T2DM may be misclassified as having type 1 (T1DM). Conversely, population becomes heavier, overweight autoimmune misdiagnosed T2DM. often associated risk factors for cardiovascular disease that already present at time diagnosis, making normalization blood...
OBJECTIVE To evaluate the frequency of depressive symptoms and diagnosis management depression in youth with type 1 diabetes (T1D) 2 (T2D) enrolled Pediatric Diabetes Consortium T1D T2D registries. RESEARCH DESIGN AND METHODS The Children’s Depression Inventory (CDI) Self-Report (Short) version was completed by 261 339 aged 10–17 years. RESULTS Symptoms were identified 13% 22% (P = 0.007) participants; these, only 4% 9% treated a therapist within prior 12 months. Depressive associated lower...
OBJECTIVE To compare races/ethnicities for characteristics, at type 1 diabetes diagnosis and during the first 3 years postdiagnosis, known to influence long-term health outcomes. RESEARCH DESIGN AND METHODS We analyzed 927 Pediatric Diabetes Consortium (PDC) participants &lt;19 old (631 non-Hispanic white [NHW], 216 Hispanic, 80 African American [AA]) diagnosed with followed a median of 3.0 (interquartile range 2.2–3.6). Demographic clinical data were collected from medical records...
OBJECTIVE—To determine if children with type 1 diabetes have increased arterial stiffness by estimating augmentation index the simple noninvasive technique of radial artery tonometry. RESEARCH DESIGN AND METHODS—We studied 98 diabetic and 57 healthy control subjects, ages 10–18 years, matched for age, sex, race, BMI, generating 43 pairs. Radial tonometry was performed, blood collected analysis fasting lipids, HbA1c, glucose, cytokines in all children. RESULTS—Children had a significantly...