Pierre‐Géraud Claret

ORCID: 0000-0003-4430-1350
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About
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Research Areas
  • Emergency and Acute Care Studies
  • Cardiac Arrest and Resuscitation
  • Ultrasound in Clinical Applications
  • Trauma and Emergency Care Studies
  • Sepsis Diagnosis and Treatment
  • Radiology practices and education
  • Airway Management and Intubation Techniques
  • COVID-19 Clinical Research Studies
  • Hemodynamic Monitoring and Therapy
  • Cardiac, Anesthesia and Surgical Outcomes
  • Respiratory Support and Mechanisms
  • Heart Failure Treatment and Management
  • Radiation Dose and Imaging
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Health, Medicine and Society
  • Healthcare Decision-Making and Restraints
  • Renal function and acid-base balance
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Healthcare Policy and Management
  • Acute Myocardial Infarction Research
  • Disaster Response and Management
  • Healthcare Systems and Practices
  • Asthma and respiratory diseases
  • Traumatic Brain Injury and Neurovascular Disturbances

Université de Nîmes
2015-2024

Université de Montpellier
2011-2024

Centre Hospitalier Universitaire de Nîmes
2015-2024

bioMérieux (France)
2024

Centre Hospitalier Universitaire de Montpellier
2022

CHU Dijon Bourgogne
2018-2022

Nantes Université
2018-2022

Centre Hospitalier Universitaire de Nantes
2018-2022

Hôpitaux Universitaires de Strasbourg
2021-2022

Creusot-Loire Entreprises (France)
2021-2022

<h3>Importance</h3> An international task force recently redefined the concept of sepsis. This recommended use quick Sequential Organ Failure Assessment (qSOFA) score instead systemic inflammatory response syndrome (SIRS) criteria to identify patients at high risk mortality. However, these new have not been prospectively validated in some settings, and their added value emergency department remains unknown. <h3>Objective</h3> To validate qSOFA as a mortality predictor compare performances...

10.1001/jama.2016.20329 article EN JAMA 2017-01-17

Abstract Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms involved still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized that infection-mediated lymphopenia could also be related to T cell apoptosis. By comparing intensive care unit (ICU) and non-ICU COVID-19 patients with age-matched healthy donors, found a strong positive correlation between plasma levels soluble FasL (sFasL) surface expression Fas/CD95 propensity cells die CD4...

10.1038/s41418-022-00936-x article EN cc-by Cell Death and Differentiation 2022-01-22

Abstract Background There have been reports of procoagulant activity in patients with COVID‐19. Whether there is an association between pulmonary embolism (PE) and COVID‐19 the emergency department (ED) unknown. The aim this study was to assess whether associated PE ED who underwent a computed tomographic angiogram (CTPA). Methods A retrospective 26 EDs from six countries. whom CTPA performed for suspected during 2‐month period covering pandemic peak. primary endpoint occurrence on CTPA....

10.1111/acem.14096 article EN Academic Emergency Medicine 2020-07-31

Summary Since the beginning of pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) gastrointestinal (GI) tract has emerged as an important organ influencing propensity to and potentially severity related COVID‐19 disease. However, contribution SARS‐CoV‐2 intestinal infection on pathogenesis remains be clarified. In this exploratory study, we highlighted a possible link between alterations in composition gut microbiota levels RNA tract, which could more than...

10.1111/1462-2920.16028 article EN cc-by-nc-nd Environmental Microbiology 2022-05-04

Introduction Erector spinae plane block has been proposed to reduce opioid use and improve pain relief with controversial results. This randomized clinical study aimed assess the efficacy of erector in major spine surgery including multimodal ‘Enhance Recovery After Surgery’ programs. Method institutional review board approval, adult patients undergoing elective lumbar standardized general anesthesia, rehabilitation analgesia protocols were randomly allocated receive bilateral...

10.1136/rapm-2022-103737 article EN Regional Anesthesia & Pain Medicine 2022-07-21

As about 10% of patients with COVID-19 present sequelae, it is important to better understand the physiopathology so-called long COVID.

10.3389/fimmu.2023.1335352 article EN cc-by Frontiers in Immunology 2024-01-03

<h3>BACKGROUND:</h3> The RAD-57 pulse CO-oximeter is a lightweight device allowing noninvasive measurement of blood carboxyhemoglobin (S<sub>pCO</sub>). We assessed the diagnostic value CO-oximetry, comparing S<sub>pCO</sub> values from to standard laboratory (COHb) in emergency department patients with suspected carbon monoxide (CO) poisoning. <h3>METHODS:</h3> This was prospective, accuracy study according Standards for Reporting Diagnostic Accuracy Studies criteria consecutive adult CO...

10.4187/respcare.02313 article EN Respiratory Care 2013-03-19

When medical wards become saturated, the common practice is to resort outlying patients in another ward until a bed becomes free. Compare quality of care provided for inpatients who are (O) inappropriate because lack vacant beds appropriate specialty given non (NO) patients. We propose matched-pair cluster study. The exposed group consisted that were outliers available beds. Non-exposed subjects (the control group) those hospitalized corresponded reason their admission. Each patient was...

10.1186/1757-7241-21-17 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2013-03-14

Ultra low dose chest computed tomography (CT) acquisitions have been used for selected emergency room patients with acute dyspnea or minor thoracic trauma. The purpose of this study was to evaluate the diagnostic performance ultra-low-dose (ULD) CT detecting viral pneumonia patterns compared standard (STD) CT.All consecutive adult two non-enhanced acquisitions, one STD and ULD, suspicion between March 5th April 2nd 2020 were included. results divided into groups: non-viral compatible based...

10.21037/qims-20-1176 article EN Quantitative Imaging in Medicine and Surgery 2021-05-13

The correlation between cardiac output (CO) evaluated by echocardiography and CO measured thermodilution (COth) varies according to different studies. A new transthoracic (TTE) tool allows automatic calculation of the subaortic velocity time index (VTIauto) (COauto). main objective was evaluate COth COauto in an anesthetized, ventilated piglet hemorrhagic shock (HS) model. secondary objectives were manual measurements VTI, preload-dependency VTIvaresp.Eighteen piglets bled until mean...

10.1097/shk.0000000000001273 article EN Shock 2018-10-09

T cell cytotoxicity plays a major role in antiviral immunity. Anti-SARS-CoV-2 immunity may determine acute disease severity, but also the potential persistence of symptoms (long COVID). We therefore measured expression perforin, cytotoxic mediator, cells patients recently hospitalized for SARS-CoV-2 infection. recruited 54 volunteers confirmed as being SARS-CoV-2-infected by RT-PCR and admitted to Intensive Care Units (ICUs) or non-ICU, 29 age- sex-matched healthy controls (HCs). Amounts...

10.3389/fimmu.2022.1029006 article EN cc-by Frontiers in Immunology 2022-10-20
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