Maternal dietary patterns before and during pregnancy play important roles in the development of gestational diabetes mellitus (GDM). We aimed to identify that are associated with GDM risk pregnant U.S. women. From a 24 h recall 253 women (16-41 years) included National Health Nutrition Examination Survey (NHANES) 2003-2012, food items were aggregated into 28 groups based on Food Patterns Equivalents Database. Three identified by reduced rank regression responses including prepregnancy body...

Although the positive association between pre-pregnancy overweight and obesity with excessive gestational weight gain is well known, it not clear how status associated through maternal diet during pregnancy. This study aimed to examine relationship quality nutritional biomarkers Our included 795 U.S. pregnant women from National Health Nutrition Examination Survey, 2003-2012. Pre-pregnancy body mass index (BMI) was calculated based on self-reported height. The cutoff points of <18.5...

Despite the various therapeutic benefits and high tolerance of orally administered silybin, poor water-solubility can be main restrictive physicochemical feature, which results in low oral bioavailability absorption. A milk thistle nanocrystal formulation (HM40) was prepared using a modified wet-milling method. Comprehensive characterization performed to determine physical morphology, crystallinity, properties. The long-term stability evaluated over 24 months. In vitro silybin release...

Our recent studies suggest that activation of the wingless-type MMTV integration site (WNT) pathway plays pathogenic roles in diabetic retinopathy and age-related macular degeneration. Here we investigated causative role oxidative stress retinal WNT an experimental model diabetes. Cultured pigment epithelial cells capillary endothelial were treated with a lipid peroxidation product, 4-hydroxynonenal (HNE), antioxidant, N-acetyl-cysteine (NAC). In vivo, rats streptozotocin-induced diabetes by...

Kallistatin is a member of the serine proteinase inhibitor superfamily. levels have been shown to be decreased in vitreous while increased circulation patients with diabetic retinopathy (DR). Overactivation Wnt pathway known play pathogenic roles DR. To investigate role kallistatin DR and activation, we generated transgenic (kallistatin-TG) mice overexpressing multiple tissues including retina. In oxygen-induced (OIR) model, overexpression attenuated ischemia-induced retinal...

This study explored the necessities, facilitators, and barriers of school-based dietary education examined strategies for its enhancement. Focus group interviews were conducted with eight home economics teachers, who play pivotal roles in delivering middle high schools. The teachers highlighted growing need due to increasing issues among adolescents, media influence, declining role families education, importance nutrition independent competence during adolescence. Facilitating factors...

There have been a limited number of studies examining the association between pre-pregnancy body mass index (BMI) and dietary inflammation during pregnancy. Our aim is to examine BMI Dietary Inflammatory Index (DII)™ C-reactive protein (CRP) concentrations The study included 631 pregnant American women from National Health Nutrition Examination Survey (NHANES) cross-sectional examinations 2003 2012. Pre-pregnancy was calculated based on self-reported weight measured height. cut-offs <18.5...

This investigation studied circulating LPS activity, potential intestinal damage, and the systemic inflammatory response (SIR) during exercise heat acclimation process. 8 healthy males (Age=24±3 years) ran in a hot environment on 5 consecutive days until core temperature (T_c) was elevated 2°C above rest. Plasma obtained pre-, post-, 1 h 3 post-exercise 1^st, 3^rd, 5^th day of analyzed for TNF-α, IL-6, IL-10, IL-1ra, LPS, fatty acid-binding protein...

The traditional Korean diet has several healthy components, including abundant vegetables, fermented foods, a variety of foodstuffs, and balance animal vegetable food intake. Although the many few studies have been conducted on health advantages dietary pattern. This study is intended to clarify relationship between patterns chronic diseases using Integrated Dietary Pattern Score (I-KDPS). I-KDPS an index for measuring based meals reflects complex multifaceted characteristics culture....

We aimed to investigate the association between dairy product consumption and risk of obesity metabolic syndrome (MetS) in Korean adults. Data from 13,692 adults aged ≥19 years KNHANES 2010–2013 were used. The study participants divided into three groups according serving size products they consumed based on a single 24-h recall. About 58% did not consume any one day. In both sexes, only those who adhered recommendation for (≥1 serving/day) achieved daily requirement calcium. Women ≥1...

Eating out has been reported to have negative effects on nutritional status. However, eating can include meals prepared at home and eaten outside. Conversely, be brought from outside, as take-out deliveries become common in Korea. Thus, we tested whether or not meal preparation location influences daily diet quality.From the Korea National Health Nutrition Examination Survey (KNHANES) 2007-2009, 4,915 Korean adults (20-64 years) were classified into two groups: home-made group (HMG), who ate...

Adequate intake of iodine is essential for proper thyroid function. Although dietary reference intakes have been established, cannot be estimated due to the lack data on contents in foods. We aimed determine if food group can predict status assessed by urinary concentration (UIC) from spot urine samples 5967 US adults National Health and Nutrition Examination Survey (NHANES) 2007–2012. From an in-person 24-h recall, all foods consumed were aggregated into 12 main groups using individual code...

Iodine is an essential component of the thyroid hormone which plays crucial roles in healthy function and lipid metabolism. However, association between iodine status dyslipidemia has not been well established at a population level. We aimed to test hypothesis that odds including elevated total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol apolipoprotein B, lowered high-density (HDL) HDL/LDL ratio are associated with urinary concentration (UIC) perspective. Data 2495...

Although the role of adiponectin and leptin in etiology metabolic syndrome (MetS) has been explored various populations, limited knowledge is available on prospective association with risk MetS development. The present study aimed to evaluate associations adiponectin, leptin, leptin-adiponectin (LA) ratio future middle-aged older Korean adults. Using a prospective, population-based Ansan-Ansung cohort Genome Epidemiology Study (KoGES), 2691 adults (1317 men 1374 women) were included study....

Although serum uric acid level and systemic inflammation have been highlighted as risk factors for type 2 diabetes mellitus (T2DM), little is known about these associations in the Korean population. Thus, we examined individual combined of (evaluated using high-sensitivity C-reactive protein [hs-CRP] measurement) with future T2DM. A total 4152 adults aged 45-76 years without T2DM, cancer, or gout at baseline 2007-2008 from Genome Epidemiology Study were followed up until 2016. Cox...

Little is known about the associations of inflammation and depression with telomere length. Using data from National Health Nutrition Examination Survey (NHANES) 1999–2002, current study assessed effects on length in 1141 young adults USA. Depression status was World Organization Composite International Diagnostic Interview measured based C-reactive protein (CRP) concentrations. Information obtained using quantitative polymerase chain reaction method to measure relative standard reference...

Purpose: The purpose of this study was to examine the prevalence food insecurity in Korean elderly and analyze health status as well nutrient intakes according status. Methods: A total 939 subjects (over 65 years old) were used our analysis from fifth 2010 National Health Nutrition Examination Survey (KNHANES V-1). variables consisted general characteristics, physical mental health, intake, rate deficient intake energy nutrients compared with Dietary Reference Intakes for Koreans (KDRIs)...

Diet plays a crucial role in cognitive function. Few studies have examined the relationship between dietary patterns and functions of older adults Korean population. This study aimed to identify effect on risk mild impairment. A total 239 participants, including 88 men 151 women, aged 65 years were selected from health centers district Seoul, Gyeonggi province, Incheon, Korea. Dietary determined using Reduced Rank Regression (RRR) methods with responses regarding vitamin B6, C, iron intakes,...

Abstract Background Acid-base homeostasis is increasingly being recognized to play an important role in normal metabolic function. However, prospective studies on the relationship between diet-induced acid-base imbalance and insulin resistance among Asian populations have been limited. Thus, we investigated whether acidosis was prospectively associated with risk middle-aged older Korean adults. Methods In total, 5406 participants from Genome Epidemiology Study without type 2 diabetes,...

The purpose of this study is to understand the current status food insecurity in Korea and US compare relationship with nutrient intake depression. Data from 2014 2013–2014 National Health Nutrition Examination Surveys were analyzed, a total 3102 Korean 3234 American adults aged 20–64 years included. Study subjects classified into three groups according degree assessed by 18-item Household Food Security Survey Module: secure (FS), mildly insecure (FI 1), moderately-to-severely 2) groups....