- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
- Pharmacology and Obesity Treatment
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Growth Hormone and Insulin-like Growth Factors
- Thyroid Disorders and Treatments
- Bone health and osteoporosis research
- Regulation of Appetite and Obesity
- Obesity and Health Practices
- Metabolism, Diabetes, and Cancer
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Nuclear Structure and Function
- Diet, Metabolism, and Disease
- Neuroendocrine Tumor Research Advances
- Sleep and Wakefulness Research
- Dysphagia Assessment and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- Esophageal and GI Pathology
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Muscle metabolism and nutrition
- Hip and Femur Fractures
- Bone health and treatments
- Diabetes Treatment and Management
Universidade Federal do Rio de Janeiro
2003-2018
Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione
2004-2017
Hospital Universitário Clementino Fraga Filho
2013
Adolescent obesity is becoming a health problem in both developed and developing countries. Antiobesity drug therapy not currently indicated for the treatment of adolescent remains investigational at this time. The aim study was to determine efficacy safety sibutramine obese adolescents. A randomized, double-blind, placebo-controlled trial, enrolling 60 adolescents, aged 14–17 yr, 6 months conducted. In first month, all patients received placebo hypocaloric diet plus exercise orientation....
Several studies point to a correlation between obesity and the severity of depressive anxiety symptoms in children adults, but there are still some controversial points about this association. The aim study is investigate relationship body composition anxiety/depressive overweight obese individuals with Metabolic Syndrome (MS). Fifty patients, 18–50 years old, or diagnosis MS based on International Diabetes Federation (IDF) criteria were selected for study. Body was evaluated using Dual...
Type 2 diabetes mellitus (T2DM) has a high prevalence and incidence around the world. The complex pathophysiology mechanism is among barriers for treatment. patients have dysfunction in incretin hormones (as glucagon-like peptide-1 or GLP-1, glucose-dependent insulinotropic polypeptide GIP). By inhibiting dipeptidyl peptidase-4 (DPP-4) enzyme, it possible to slow inactivation of GLP-1 GIP, promoting blood glucose level reduction manner. Linagliptin highly specific potent inhibitor DPP-4 that...
A síndrome metabólica (SM) é caracterizada por alterações no metabolismo glicídico, obesidade, hipertensão e dislipidemia. Estas metabólicas interrelacionam-se com diversos eixos endócrinos controlados pelo hipotálamo pela hipófise. obesidade central parece relacionar-se a uma hiperativação do eixo hipotálamo-hipófise-adrenal, como também sistema nervoso simpático, que poderia levar um quadro de hipercortisolismo sub-clínico arterial. SM estado hipo-somatotropismo relativo relacionado à...
Lipodystrophies are acquired or inherited disorders characterized by selective generalized loss of adipose tissue. Affected patients predisposed to insulin resistance and metabolic complications (1). Noticeably, with hereditary forms extremely resistant (2,3). On the other hand, in partial ample phenotypic spectrum determines clinical presentations profiles variable degrees (4). Among diagnostic resources for fat distribution evaluation, dual-energy X-ray absorptiometry (DEXA) has been...
To investigate the relationship between serum thyrotropin (TSH), insulin resistance (IR), and cardiovascular risk factors (CRF) in a sample of overweight obese Brazilian adolescents.A retrospective, longitudinal analysis 199 pubescent adolescents was performed. The TSH free T4 (fT4) levels, anthropometric measurements, laboratory test results these patients were analyzed.27 individuals (13.56%) presented with levels above normal level (subclinical hypothyroidism [SCH]). Their waist...
Obesity is a worldwide public health issue with negative impact on quality of life. Different weight loss interventions have demonstrated improvements in The aim this study was to investigate the effect 6 months treatment an intragastric balloon (IGB) health-related life (HRQOL) and its relation changes body fat obese individuals metabolic syndrome (MS). Fifty patients MS aged 18–50 were selected for IGB months. Body assessed anthropometric measures dual-energy X-ray absorptiometry (DXA) at...
The aim of this study was to investigate the effects a 6-month treatment with intragastric balloon (IGB) on body composition and depressive/anxiety symptoms in obese individuals metabolic syndrome (MS).Fifty patients (aged 18-50 years) obesity MS were selected for IGB 6 months. Body verified dual-energy X-ray absorptiometry (DXA) at baseline right after removal. Anxiety/depressive assessed Beck Depression Inventory (BDI) hospital anxiety depression scale (HADS) months treatment.In total, 39...
Background: Obesity is a worldwide epidemic that difficult to control with non-invasive treatments, which usually present poor results. In this context, the intragastric balloon (IGB) an important tool presents mean body weight loss (BWL) estimated at approximately 12%, although individual responses are highly variable. Objectives: This study assesses whether there factors can predict IGB therapy either before or early after placement of device. Materials and Methods: A total 50 obese...
To investigate the relationship between serum thyrotropin (TSH), insulin resistance (IR), and cardiovascular risk factors (CRF) in a sample of overweight obese Brazilian adolescents. A retrospective, longitudinal analysis 199 pubescent adolescents was performed. The TSH free T4 (fT4) levels, anthropometric measurements, laboratory test results these patients were analyzed. 27 individuals (13.56%) presented with levels above normal level (subclinical hypothyroidism [SCH]). Their waist...