A5012790504- Bone health and osteoporosis research
- Vitamin D Research Studies
- Bone health and treatments
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Parathyroid Disorders and Treatments
- Bariatric Surgery and Outcomes
- Bone Metabolism and Diseases
- Nutrition and Health in Aging
- Pharmacological Effects and Toxicity Studies
- HIV-related health complications and treatments
- Obesity, Physical Activity, Diet
- Body Composition Measurement Techniques
- Systemic Lupus Erythematosus Research
- Adrenal and Paraganglionic Tumors
- Bone and Joint Diseases
- Thyroid and Parathyroid Surgery
- Hormonal Regulation and Hypertension
- Scoliosis diagnosis and treatment
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Birth, Development, and Health
- Tendon Structure and Treatment
- Obesity and Health Practices
- TGF-β signaling in diseases
- Hip and Femur Fractures
Universidade Federal do Rio de Janeiro
2014-2023
Hospital Universitário Clementino Fraga Filho
2010-2022
McGill University
2017
Sociedade Brasileira de Ortopedia e Traumatologia
2017
Governo do Estado do Rio de Janeiro
2013
Sociedade Brasileira de Pediatria
2008-2012
Acromegaly is one of the causes secondary osteoporosis, although studies bone mineral density (BMD) have yielded conflicting results and none them evaluated properties.Our objective was to correlate, in a cohort 82 acromegalic patients, BMD microarchitecture, using dual-energy x-ray absorptiometry high-resolution peripheral quantitative computed tomography, with presence type 2 diabetes mellitus (T2DM), disease activity, gonadal status compare these parameters between 45 eugonadal patients...
Osteoporosis is the leading cause of fractures in population older than 50 years. This silent disease affects primarily postmenopausal women and elderly, morbidity mortality rates are high. The main goal treating osteoporosis prevention fractures. identification populations at risk through early diagnosis treatment essential. last Brazilian guideline for was elaborated 2002. Since then, new strategies stratification have been developed, drugs with novel action mechanisms added to therapeutic...
Os glicocorticoides (GC) são prescritos por praticamente todas as especialidades médicas, e cerca de 0,5% da população geral do Reino Unido utiliza esses medicamentos. Com o aumento sobrevida dos pacientes com doenças reumatológicas, a morbidade secundária ao uso dessa medicação representa um aspecto importante que deve ser considerado no manejo nossos pacientes. As incidências fraturas vertebrais não elevadas, variando 30%-50% em pessoas usam GC mais três meses. Assim, osteoporose...
A osteoporose é a principal causa de fraturas na população acima 50 anos. É uma doença silenciosa que afeta especialmente as mulheres pós‐menopausa e idosos tem elevada taxa morbimortalidade. O objetivo do tratamento da prevenção das fraturas. identificação dessa risco através diagnóstico precoces fundamental importância. última diretriz brasileira para em foi elaborada 2002. Desde então foram desenvolvidas novas estratégias osteoporose, bem como fármacos com novos mecanismos ação...
HIV infection and antiretroviral therapy (ART) may create unique risk factors for vitamin D insufficiency, including alterations of metabolism by ART. We prospectively compared demographic clinical parameters between sufficient insufficient HIV-infected (HIV+) adults, assessed changes in these among participants following standardized supplementation. HIV+ adults (≥18 years old) with HIV-1 RNA <50 copies/mL on ART were enrolled. Vitamin sufficiency insufficiency defined as 25-hydroxyvitamin...
Osteoporosis is a serious and underestimated complication of endogenous hypercortisolism that results in an increased risk fractures, even patients with normal or slightly decreased bone mineral density (BMD). Alterations microarchitecture, very important component quality, may explain fragility. The aim this study was to investigate microarchitecture cohort Cushing's syndrome (CS).Cross-sectional study.Thirty active CS fifty-one age-, sex- body mass index-matched controls were...
OBJECTIVE: To evaluate the influence of obesity, age, and years since menopause on bone density. METHODS: A retrospective analysis mineral density (BMD) obtained from 588 women, 41 to 60 years, previously menopaused (1-10 before). RESULTS: Positive obesity was confirmed by significant differences in BMD at lumbar spine, femoral neck (FN), trochanter (TR) between groups (p < 0.01). Age (YSM) were negatively correlated with all sites = 0.000). Comparing patients within 1 6 YSM versus 10...
To assess the prevalence and factors associated with low bone mineral density (BMD) in HIV-infected adolescents.This was a cross-sectional study of Brazilian cohort vertically adolescents. Body composition lumbar spine (LS) total body (TB) BMD were estimated by dual-energy X-ray absorptiometry (DXA). Low considered for Z-score ≤-2 standard deviations. Pubertal development, anthropometric data, laboratory measurements, antiretroviral regimen, time immunological virological recovery evaluated...
Background. Overweight, hyperandrogenism and insulin resistance are cardinal features of patients with polycystic ovary syndrome (PCOS). Women PCOS have excess accumulation trunkal fat metabolic complications. Recent findings suggest that peripheral may protective behaviour. The aim this study was to investigate body distribution in associations hormonal profile.Methods. included 24 a control group 13 women. Anthropometrical evaluation dual-energy X-ray absorptiometry determine composition...
The role of vitamin D on bone microarchitecture and fragility is not clear.To investigate whether deficiency (25(OH)D <20 ng/mL) increases cortical loss the severity fractures.Cross-sectional study 287 elderly women with at least one prevalent low-impact fracture.Biochemistry, X-rays to identify vertebral fractures (VFs) confirm non-vertebral (NonVFs), high-resolution peripheral quantitative computed tomography (HR-pQCT) evaluate microstructure.Serum 25(OH)D levels were associated body mass...
Data regarding high-resolution peripheral quantitative computed tomography (HR-pQCT) in patients with adrenal incidentaloma (AI) are unknown.To evaluate the areal bone mineral density (aBMD), microstructure, and fractures nonfunctioning AI (NFAI) autonomous cortisol secretion (ACS).We evaluated 45 NFAI (1 mg dexamethasone suppression test [DST] ≤1.8 µg/dL) 30 ACS DST 1.9-5.0 µg/dL). aBMD was measured using dual-energy X-ray absorptiometry; vertebral fracture by spine X-ray; geometry,...