A5072140549- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Polymer composites and self-healing
- DNA and Nucleic Acid Chemistry
- Flame retardant materials and properties
- RNA Interference and Gene Delivery
- Synthesis and properties of polymers
- biodegradable polymer synthesis and properties
- Silicone and Siloxane Chemistry
- Carbon dioxide utilization in catalysis
- Advanced Biosensing Techniques and Applications
- Fluoride Effects and Removal
- Thermal Radiation and Cooling Technologies
- Advanced Thermoelectric Materials and Devices
- Heavy metals in environment
- Adsorption and biosorption for pollutant removal
- Phosphorus and nutrient management
- Polymer crystallization and properties
- Coagulation and Flocculation Studies
- Constructed Wetlands for Wastewater Treatment
- Advanced Polymer Synthesis and Characterization
- Aerogels and thermal insulation
- Bacteriophages and microbial interactions
- Advanced Materials and Mechanics
- Gold and Silver Nanoparticles Synthesis and Applications
Affiliated Hospital of North Sichuan Medical College
2022-2025
North Sichuan Medical University
2023-2025
Xi'an Jiaotong University
2025
University of Science and Technology of China
2023-2024
Beijing University of Chemical Technology
2024
Chinese Academy of Sciences
2018-2023
Jiangnan University
2023
Hebei Medical University
2022
Second Hospital of Hebei Medical University
2022
Sichuan University
2016-2021
Traditional commercial thermosetting materials are currently facing significant challenges in terms of reprocessing, degradation, and recycling because a large demand petroleum resources, leading to environmental burden. In our work, trialdehyde monomer synthesized by renewable resource reacted with 1,4-Bis(4-amino-2-trifluoromethylphenoxy)benzene 1,4-Bis(4-aminophenoxy)benzene form dynamic cross-linked network called BQPs. The fluorinated biobased polyimine material exhibits exceptional...
Clinical observations have revealed that patients undergoing organ transplantation administered tacrolimus often experience abnormal lipid metabolism with serious consequences. Thus, the intricate interplay between and must be addressed to develop targeted therapeutic interventions. Our ongoing research aims precision medicine approaches not only alleviate immediate repercussions for transplant but also enhance their long-term outcomes. To this end, we investigated potential genes associated...
A rapid signal amplification system based on the self-replicating catalyzed hairpin assembly is reported in which two hairpins, H1 and H2, were well-designed split target/trigger DNA G-quadruplex sequences respectively integrated into H2. Target/trigger can be cyclically used this to form duplex assemblies (H1–H2), will bring fragments close-enough proximity induce formation of intact as a colorimetric readout. Similarly, reunite sequence that identical DNA; then, obtained replica also new...
Abstract Reversible and recyclable thermosets have garnered increasing attention for their smart functionality sustainability. However, they still face challenges in balancing comprehensive performance dynamic features. Herein, silicon (Si)─oxygen (O) imidazole units covalent bonds are coupled to generate a new class of bio‐polyimines (Bio‐Si‐PABZs), endow them with high excellent reprocessing capability acid‐degradability. By tailoring the molar content diamines, this Bio‐Si‐PABZs displayed...
Polymer aerogels, with their porous and lightweight features, excel in applications such as energy storage, absorption, thermal insulation, making them a sought-after new material. However, the covalent cross-linking networks of current polymer aerogels result unsustainable manufacturing processing practices, persistently depleting our finite natural resources causing significant global environmental impacts. Herein, we have constructed high-performance dynamic aerogel network using biobased...
As novel noncoding small RNA molecules, piRNAs play crucial roles in cancer development. However, due to their short sequences, easy degradation, and low abundance, developing specific detection methods is challenging. Rapid early important for the clinical of tumours. Here, a one-step, dual-signal amplification piRNA system based on sliding replication catalytic hairpin assembly (CHA), termed CTA, was developed rapid, ultrasensitive piRNA-823. By utilizing unique characteristics tandem...
It is known that the adsorption of short single-stranded DNA (ssDNA) on unmodified gold nanoparticles (AuNPs) much faster than for long ssDNA, and thus leads to length-dependent AuNPs aggregation after addition salt, color solutions sequentially changed from red blue in accordance with increase ssDNA length. However, we found herein sticky end hairpin exhibited a completely different behavior compared an inverse blue-to-red variation was observed colloid solution length when within certain...
A rapid room-temperature DNA nanowires preparation strategy on the basis of self-replicating catalyzed hairpin assembly (SRCHA) was reported. In this system, three probes (P1, P2, and P3) were well-designed partially hybridize to each other, two split trigger sequences integrated into P1 P3, respectively. When SRCHA initiated by DNA, a series steps based toehold-mediated strand displacement activated, Y shaped (P1-P2-P3) formed. that case, will come close-enough proximity form replicas,...
One-dimensional DNA polymer chains were obtained based on the catalyzed hairpin assembly and sticky end self-assembly, which led to a signal amplified colorimetric nucleic acid assay.
Abstract Background Isothermal amplification is considered to be one of the most promising tools for point-of-care testing molecular diagnosis. However, its clinical application severely hindered by nonspecific amplification. Thus, it important investigate exact mechanism and develop a high-specific isothermal assay. Methods Four sets primer pairs were incubated with Bst DNA polymerase produce Gel electrophoresis, sequencing, sequence function analysis used product generation, which was...