A5066624658- Biological Activity of Diterpenoids and Biflavonoids
- Natural Compound Pharmacology Studies
- Medicinal Plants and Neuroprotection
- Rural Development and Agriculture
- Synthesis of Organic Compounds
- Agricultural and Food Sciences
- Insect Pest Control Strategies
- Phytochemicals and Medicinal Plants
- Essential Oils and Antimicrobial Activity
- Lipid metabolism and disorders
- Ethnobotanical and Medicinal Plants Studies
- Medical Imaging Techniques and Applications
- Toxin Mechanisms and Immunotoxins
- Trypanosoma species research and implications
- Acupuncture Treatment Research Studies
- Radiopharmaceutical Chemistry and Applications
- Insect Utilization and Effects
- Complementary and Alternative Medicine Studies
- Phytochemical compounds biological activities
- Pain Management and Placebo Effect
- Research on Leishmaniasis Studies
- Ginseng Biological Effects and Applications
- Medical Imaging and Pathology Studies
Fundação Oswaldo Cruz
2017-2024
Natura (Brazil)
2024
Universidade do Estado do Rio de Janeiro
2005-2022
Carapa guianensis (Andiroba, Meliaceae) is considered a multipurpose tree. In Brazil, Indigenous people have used it as insect repellent and in the treatment of various diseases. Most biological activities popular uses are attributed to limonoids, which highly oxygenated tetranortriterpenoids. More than 300 limonoids been described Meliaceae family. Limonoids from Andiroba oil shown high anti-inflammatory anti-allergic vivo, by inhibiting platelet activating factors many inflammatory...
Plants have been used for the human beings as food, additives and/or medicines. There are controversies about biological effects of several natural products and, it is worthwhile to try develop experimental assays evaluate properties extracts plants. Pfaffia sp. utilized in popular medicine and various attributed its extract. Red blood cells (RBC) plasma proteins labeled with technetium-99m (Tc-99m) this labeling procedure depends on a reducing agent stannous ion usually used. reports that...
, a Brazilian native species from the Solanaceae family, is recognized as promising source of bioactive withanolides, particularly Aurelianolide A and B, which exhibit significant antitumoral activities. Despite its potential, research on chemical constituents this remains limited. This study aimed to dereplicate extracts partitions
Chagas disease (CD) affects more than 6 million people worldwide. The available treatment is far from ideal, creating a demand for new alternative therapies. Botanical diversity provides wide range of novel potential therapeutic scaffolds. Presently, our aim was to evaluate the mammalian host toxicity and anti-Trypanosoma cruzi activity botanic natural products including extracts, fractions purified compounds obtained Brazilian flora. In this study, 36 samples extracts eight pure seven plant...
In clinical acupuncture, when acupuncture points are stimulated, several types of reflex responses can be evoked. Consequently, different categories physiological induced, which include changes in the activities internal organs and tissues. The point Sanyinjiao (SP6) has been used successfully to treat human gastrointestinal conditions. aim this work was investigate effects end-organ response induced by SP6 on bioavailability radiopharmaceutical sodium pertechnetate ( Na 99 m TcO 4 ) Wistar...
belongs to the Solanaceae family and is a promising source of cytotoxic withanolides known as aurelianolides A B. In last years, pharmacological studies these on different leukemia cell lines have stimulated new their potential alternative candidates for lead anticancer drugs. However, obtention two pure compounds by traditional preparative costly long time-consuming process, which performed in several steps. This study aimed propose straightforward approach isolating B using high-speed...
A bioprospecção é uma das formas de extrair valor econômico da biodiversidade brasileira, abrangendo principalmente a indústria farmacêutica. O câncer principais causas mortalidade no mundo e 64,9% drogas anticâncer, aprovadas 1946 2019, são origem natural. família Clusiaceae possui vários metabólitos secundários bioativos, destacando-se ação antineoplásica espécies dos gêneros Garcinia Clusia. objetivo deste trabalho foi realizar breve revisão atividade anticâncer Clusia Garcinia,...
O projeto PROFITO, criado em 2006 pelo Laboratório da Biodiversidade (PAF/NGBS/FIOCRUZ), parceria com os agricultores do Parque Estadual Pedra Branca (PEPB), envolveu a criação de um arranjo produtivo plantas medicinais para geração trabalho e renda. Este é estudo caso realizado através uma revisão bibliográfica não exaustiva 2015, identificando principais entraves, as estratégias enfrentamento das barreiras desafios soluções encontradas. Alguns problemas encontrados foram: conscientização...
O presente trabalho é um estudo de caso do projeto Profito, que se iniciou em 2006, vinculada ao Laboratório da Biodiversidade (PAF/NGBS/Fiocruz) parceria com o Instituto Três Rios (UFRRJ) e os agricultores Parque Estadual Pedra Branca (PEPB), destacando a importância deste como exemplo prático inovação. Foi utilizada uma metodologia qualitativa, teve base coleta informações, partir revisão bibliográfica não exaustiva 2006 2015. Profito envolveu capacitação dos sobre formas plantio,...