A5016534607- Nanoparticles: synthesis and applications
- Chemical and Physical Properties in Aqueous Solutions
- Photochemistry and Electron Transfer Studies
- Quantum Dots Synthesis And Properties
- Thermodynamic properties of mixtures
- Phytochemistry and Biological Activities
- Computational Drug Discovery Methods
- Cancer-related Molecular Pathways
- Surfactants and Colloidal Systems
- Advanced biosensing and bioanalysis techniques
- Natural product bioactivities and synthesis
- Crystallization and Solubility Studies
- RNA Interference and Gene Delivery
- Free Radicals and Antioxidants
- Gold and Silver Nanoparticles Synthesis and Applications
- CRISPR and Genetic Engineering
- T-cell and B-cell Immunology
- Analytical Chemistry and Chromatography
- Alzheimer's disease research and treatments
- Phytochemicals and Medicinal Plants
- Carbon and Quantum Dots Applications
- Plant-derived Lignans Synthesis and Bioactivity
- Southeast Asian Sociopolitical Studies
- Porphyrin and Phthalocyanine Chemistry
- DNA Repair Mechanisms
University of Calcutta
2012-2025
Visva-Bharati University
2004-2023
West Bengal University of Animal and Fishery Sciences
2023
Kyoto University
2014-2021
Solvation thermodynamic data of<sc>dl</sc>-serine and<sc>dl</sc>-phenylalanine in aqueous mixtures of dimethylsulfoxide at 298.15 K were determined from solubility measurement.
This research performs density functional theory/QTAIM calculations at the B3LYP/6-31G (d,p) and MPW1PW91/6-31G levels to assess interactions of chloropicrin with B12N12 fullerene-like nanocages, as well Al Ga doped nanocages. The maximum adsorption energy in B3LYP method is −110.95 kJ/mole (−91.98 BSSE corrected), whereas, MPW1PW91 method, −113.59 (−96.60 indicating that these are chemisorption types. Because chemical interaction stated molecules, our analysis reveals has higher energy,...
Pancytopenia is a medical condition where there decrease in cell count from all three lineages bone marrow resulting anaemia, leukopenia, and thrombocytopenia. It usually due to the underlying disease process affecting or peripheral blood cells. To study patients suffering pancytopenia evaluate clinical presentation, haematological &amp; biochemical features, complications, outcome of patients. The present was prospective observational study. In series 6 cases, we found case each...
Significance This paper demonstrates that activation-induced cytidine deaminase (AID), an essential enzyme in antigen-induced antibody diversification, forms distinct ribonucleoprotein complexes depending on its structural states: namely monomers or dimers. The identified RNA-binding proteins are required for the function of AID: DNA cleavage recombination. In addition, complex formation between AID and heterogeneous nuclear ribonucleoproteins (hnRNPs) is RNA-dependent.
Significance The B-cell–specific antibody gene-diversifying enzyme activation-induced cytidine deaminase (AID) shows high homology with apolipoprotein B mRNA-editing catalytic polypeptide 1 (APOBEC1), which edits B-100 mRNA in the presence of cofactor APOBEC1 complementation factor/APOBEC factor (A1CF/ACF). Here we show that DNA cleavage and recombination functions AID depend critically on its RNA-dependent interaction distinct heterogeneous nuclear ribonucleoprotein (hnRNP) cofactors....
A dramatic reduction in the excited-state intramolecular proton transfer (ESIPT) rate is observed for 3-hydroxyflavone (3-HF) within nanoscopic polar domains of Aerosol-OT (AOT)/n-heptane reverse micelle solutions. It attributed to formation intermolecularly hydrogen-bonded 3-HF:AOT complexes, which cause a significant disruption hydrogen bonding complex-bound 3-HF molecules, thereby limiting overall ESIPT process. Introduction strong hydrogen-bonding solvents like water or methanol into...
Significance Uracil DNA glycosylase (UNG) has been known as a critical base excision repair protein required for class switch recombination (CSR) and somatic hypermutation (SHM). On the other hand, its precise function in both CSR SHM is extremely debatable elusive. Here, we showed that UNG suppresses S region (s-SHM) by recruiting faithful complex and, absence of UNG, error-prone induces s-SHM overrides. Moreover, promotes activation-induced cytidine deaminase-induced regulating S-S synapse...
The present study was undertaken to investigate the food-drug interaction of carbamazepine (CBZ). Common fruit juices [grapefruit juice (GFJ), lime (LJ)], known inhibit enzyme cytochrome P450 3A4 (CYP3A4), and some widely consumed beverages [milk (M), black tea (BT)] were involved in this presence CBZ, as might happen during clinical therapy. effects on pharmacokinetics drug-induced toxicity CBZ observed after concomitant administration for a period 28 days. Accordingly, influence altered...
Flavonol 4'-chloro,3-hydroxyflavone (Cl-3HF) has been investigated in solvents of varying polarity and hydrogen-bonding capacity as well aqueous micelle solutions. Quantum chemical calculations indicate that although the Cl-atom at 4'-position 2-phenyl ring weakly perturbs electron distribution parent 3-hydroxyflavone, nuclear framework remains largely intact, excited state intra-molecular proton-transfer (ESIPT) is feasible. The ESIPT process both polar micelles was found to be fast...
4′-N,N-Dimethylamino-3-hydroxyflavone (DMAHF), a synthetic fluorescent flavone analogue with potent antioxidant activity, was explored as molecular rotor-like fluoroprobe for amyloid aggregations, causative factor in Alzheimer's disease, Parkinson's type-2 diabetes, etc. During its interactions (human) insulin aggregation (IAA), microenvironment changed. This instigated drastic change excited-state intramolecular proton transfer-based dual emission behavior, which tracked to monitor probing...