A5020628878- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Facial Trauma and Fracture Management
- Tracheal and airway disorders
- Surgical Simulation and Training
- Anatomy and Medical Technology
- Oral and Maxillofacial Pathology
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Face recognition and analysis
- Treatment of Major Depression
- Congenital Anomalies and Fetal Surgery
- Ophthalmology and Eye Disorders
- Generative Adversarial Networks and Image Synthesis
- Anesthesia and Neurotoxicity Research
- Head and Neck Surgical Oncology
- Forensic Anthropology and Bioarchaeology Studies
- Bone Tumor Diagnosis and Treatments
- Urological Disorders and Treatments
- Breast Implant and Reconstruction
- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- Hearing, Cochlea, Tinnitus, Genetics
- Head and Neck Cancer Studies
- Soft tissue tumor case studies
University of Basel
2019-2025
University Hospital of Basel
2019-2025
University Children’s Hospital Basel
2024-2025
Cleft lip and palate are one of the most common congenital craniofacial malformations. As an initial treatment, presurgical orthopedics is considered standard treatment at many cleft centers. Digital impressions becoming feasible in care. Computer-aided design (CAD) three-dimensional (3D) printing manufacturing standards dentistry. The assimilation these technologies has potential to alter traditional workflow for fabrication customized orthopedic plates. We present a digital comprising...
Palatal morphology in patients with clefts can be accurately assessed during the presurgical period, providing insights into how cleft type affect palatal development. These early observations are unbiased by treatment, making them broadly applicable. This study aimed to identify differences among untreated various types before surgery. Primary outcomes included size at occlusal plane and surface area, while secondary involved width, length, premaxilla rotation. Digital impressions from 150...
Abstract Purpose This study investigates the effectiveness of synthetic training data in predicting 2D landmarks for 3D intraoral reconstruction cleft lip and palate patients. We take inspiration from existing landmark prediction techniques faces demonstrate their potential medical applications. Methods generated both real datasets scans videos. A convolutional neural network was trained using a negative-Gaussian log-likelihood loss function to predict corresponding confidence scores. The...
Summary: Documentation of patients with cleft lip and palate (CLP) presents a significant challenge due to the necessity for consistent, high-quality imaging throughout extended treatment period. The use traditional intraoral mirrors typically necessitates an assisting person retraction lips, cheeks, mirror fogging cleaning. This results in variable fields view high personal resources. Distance measurements are not possible on conventional photographs, limiting their objective analysis. To...
OBJECTIVE Craniosynostosis is ideally treated within the 1st year of life to correct physical deformity, achieve optimal aesthetic head shape, and facilitate normal neurocognitive development. While objective assessments have been widely studied, limited reports on long-term parent-reported outcomes (PROs) exist. The authors herein report follow-up after open midline strip craniectomy with barrel stave osteotomies (BSOs) occipital release nonsyndromic sagittal craniosynostosis (SC),...
Summary: The traditional method of capturing cleft lip and palate morphology using dental impressions plaster casts has long been considered the gold standard. However, especially for infants, digital have proven to be accurate safe. We present a protocol successfully adopted by 2 centers that utilize intraoral scanners care in an outpatient setting, as well operating theater. demonstrate positioning patient, scanner, monitor, clinician, along with technical steps capture impression lip,...
Presurgical orthopedic plates are widely used for the treatment of cleft lip and palate, which is most common craniofacial birth defect. For traditional plate fabrication, an impression taken under airway-endangering conditions, recent digital alternatives overcome via intraoral scanners. However, these demand proficiency in 3D modeling software addition to generally required clinical knowledge design.We address limitations with a data-driven fully automated pipeline, endowed graphical user...
Presurgical plate therapy has been widely accepted as a treatment prior to palatal cleft closure. The effects of passive presurgical on morphology single-stage unilateral lip and palate (UCLP) repair were quantified.
Methods to assess three-dimensionally the breast surface are increasingly used in plastic and reconstructive surgery. The aim of this study was validate use Structure Sensor 3D scanner (Occipital, Inc., Boulder, CO, USA) connected an iPad Pro (Apple, Cupertino, CA, as a novel, inexpensive handheld three-dimensional scanning process.Surface images medical human female anatomy torso model rigid were repeatedly acquired with compared those obtained using two clinically established imaging...
The aim of this cohort study was to quantify the morphological changes in palatal cleft and true areas with passive plate therapy using a new analysis method based on three-dimensional standardized reproducible landmarks. Forty-five casts 15 consecutive patients complete unilateral lip palate were laser scanned investigated retrospectively. landmarks coordinate system defined, interrater intrarater measurement errors within 1.0 mm. area after period 8 months without prior surgery are...
<ns3:p><ns3:bold>Background:</ns3:bold> Cancer is the second leading cause of death globally. Up to 86% advanced cancer patients experience significant pain, while 10-20% live in chronic pain. Besides, increasing prescription opioids resulted 33,000 deaths US 2015. Both reduce patients’ functional status and quality life. While survival rates are increasing, therapeutic options for opioid refractory pain still limited. Esketamine s-enantiomer ketamine, with superior analgesic effect less...
The study aims at assessing wound healing and safety of single-stage two-layers continuous closure in patients with unilateral cleft lip palate (UCLP). In this retrospective, descriptive cohort study, we assessed without fistula formation 1, 3, 6 months after a two-layer UCLP repair, which the midline suture is continuously circular all along oral nasal sides. We examined lengths hospital stay incidence intra- postoperative adverse events. Furthermore, compared width birth on day surgery,...
We demonstrate pre-epiglottic baton plate as non-invasive treatment modality for initial airway management in newborns with Pierre Robin Sequence. A case example illustrates of upper obstruction and feeding using digital technology to facilitate customization. Laryngoscope, 134:4766-4769, 2024.
Cleft lip and palate is the most common craniofacial birth anomaly requires surgery in first year of life. However, training opportunities are limited. The aim this study was to present evaluate an open-source cleft hybrid (casting three-dimensional (3D) printing) simulation model which can be replicated at low cost facilitate teaching anatomy techniques.
To evaluate the performance of smartphone scanning applications (apps) in acquiring 3D meshes cleft palate models. Secondarily, to validate a machine learning (ML) tool for computing automated presurgical plate (PSP).
Primary alveolar bone grafting inhibits craniofacial growth. However, its effect on growth in one-stage cleft lip and palate protocols is unknown. This study investigated whether primary performed during unilateral repair negatively affects up to 6-11 years old.The growth, dental arch relationship palatal morphology at old children with were compared retrospectively. Two cohorts after a protocol without (Group A) B) the same center compared. Further, cephalometric measurements for an...
OBJECTIVE The main indication for craniofacial remodeling of craniosynostosis is to correct the deformity, but potential increased intracranial pressure resulting in neurocognitive damage and neuropsychological disadvantages cannot be neglected. relapse rate after fronto-orbital advancement (FOA) seems high; however, date, objective measurement techniques do not exist. aim this study was quantify outcome FOA using computer-assisted design (CAD) manufacturing (CAM) create individualized...
Background: Common surgical techniques aim to turn the entire vomerine mucosa with vomer flaps either oral side or nasal side. The latter approach is widely performed due similarity in color mucosa. However, we lack a histologic description of curved cleft lip and palate malformations. Methods: We histologically examined an excess 8 patients using hematoxylin–eosin, periodic acid–Schiff, Elastin van Gieson, Alcian blue stains. Tissue samples were obtained during surgery at months age....
The primary correction of congenital complete unilateral cleft lip and palate (UCLP) bilateral (BCLP) is challenging due to inherent lack palatal tissue small extent the shelves at birth. deficiency affects nasal mucosa, maxillary bone mucosa. This condition has driven evolution several surgical non-surgical techniques for mitigating problem anatomical deficits. These share common principle altering neighboring tissues around defect area in order form a functional seal between oral cavity....
Documenting complex three-dimensional (3D) cleft lip and palate malformation with plaster casts based on maxillary impressions is standard care. Presurgical orthopedic treatment also requires an impression. Digital impression-taking in patients feasible, but procurement costs hinder clinical implementation. Individualized impression trays allow for a precise impression, limiting airway risk. The authors present open-source tray library scalable not requiring 3D modeling knowledge. accessible...