A5091398864- Renal Diseases and Glomerulopathies
- Gestational Trophoblastic Disease Studies
- Parathyroid Disorders and Treatments
- Vitamin D Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Neurological and metabolic disorders
- Blood groups and transfusion
- Metamaterials and Metasurfaces Applications
- Systemic Lupus Erythematosus Research
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Pregnancy and Medication Impact
- Platelet Disorders and Treatments
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Neurological Disease Mechanisms and Treatments
- Gastric Cancer Management and Outcomes
- Terahertz technology and applications
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Esophageal Cancer Research and Treatment
- Advanced Antenna and Metasurface Technologies
- Neurological Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Flavonoids in Medical Research
- Orthopedic Infections and Treatments
Wenzhou Medical University
2008-2025
First Affiliated Hospital of Wenzhou Medical University
2008-2025
Sichuan University
2025
Shandong Provincial QianFoShan Hospital
2015-2024
Shandong First Medical University
2022-2024
West China Medical Center of Sichuan University
2020
Soochow University
2019
First Affiliated Hospital of Soochow University
2019
Shandong University
2012-2016
Capital Normal University
2016
Chronic hepatitis B (CHB) patients who have sustained virological suppression (SVS) still develop hepatocellular carcinoma(HCC), and the risk factors for developing HCC in these are not fully understood. This study included a total of 5234 achieved SVS. After SVS, incidence rate was 1.9% 1-8 years 1.33% 9-16 years. There significant difference between two periods (P < 0.001). after multivariate analysis IPTW adjustment, related to occurrence were men, hypertensive patients, diabetes high...
There were few related studies aiming to severe IgA nephropathy (IgAN) which could progress rapidly end stage renal disease (ESRD) within ten years. To find valuable clinical or pathological factors and promising precautions is essential. A single center case–control study was performed. Fifty ESRD patients with the primary cause of IgAN a short survival time less than years after diagnose enrolled in case group. One hundred more control Oxford classification scores, data at baseline during...
The long-term association between serum albumin-to-creatinine ratio (sACR) and poor patient outcomes in acute myocardial infarction (AMI) remains unclear. This study aimed to determine whether sACR was a predictor of survival patients with AMI.This AMI the emergency department (ED) from retrospective multicenter for early evaluation chest pain (REACP) study. were categorized into tertiles (T1, T2, T3) based on admission (0.445 0.584 g/μmol). Baseline at ED predictive adverse outcomes....
Gastric cancer (GC) is the fourth most common malignant human cancer. So far, molecular mechanisms underlying tumorigenesis of GC are not completely understood. Here, we reported significantly higher levels serum insulin-like growth factor (IGF)-1 in patients and phosphorylated IGF-1 receptor (IGF-1R) specimen. Moreover, induced phosphorylation IGF-1R then its downstream Akt cells. Further, IGF-1/Akt-induced forkhead box protein O1 (FoxO1) nuclear exclusion, but mTOR phosphorylation, was...
In the present study, we describe a novel and straightforward approach to produce cyclic- arginine-glycine-aspartic (RGD)-peptide-conjugated quantum dot (QD) probe as an ideal target tumor biomarker. Due its specific structure, can be used for targeted imaging of pancreatic carcinoma cells.Pancreatic cells were routinely cultured marked with QD-RGD probe. The on fluorescence-labeled cancer cell was observed by fluorescence microscopy laser confocal microscopy. Cancer viability detected MTT...
This study aims to investigate peroxiredoxin 3 (PRDX3) expression in gastric cancer tissue and its effects on cisplatin resistance cells possible mechanism.PRDX3 human microarrays was detected via immunohistochemistry. The PRDX3 small interfering RNA (siPRDX3 group) the negative control siNC (siNC were transfected into AGS MKN-74 cell lines, respectively, whereas a blank group set up. Each treated with different concentrations (0, 5, 10, 15, 20, 25, 30 μg/ml), half-inhibitory concentration...
Background: The purpose of this study was to investigate the cancer incidence in patients with end-stage aristolochic acid nephropathy (AAN). Methods: A total 102 AAN treated our hospital between 2004 and 2013 were included study. correlation age, gender, dosage (AA), type renal replacement therapies, polymorphisms quinone oxidoreductase 1 (NQO1) C609T cytochrome P450 1A1 (CYP1A1) A4889G examined. Results: rate 41.2% (42 102) including 39 cases urinary cancer. mortality significantly higher...
The long-term predictive ability of acute kidney injury (AKI) classification based on "Kidney Disease: Improving Global Outcomes"(KDIGO) AKI diagnosis criteria has not been clinically validated in diffuse proliferative lupus nephritis (DPLN) patients with AKI. Our objective was to assess the value KDIGO DPLN AKI.Retrospective cohort study conducted by reviewing medical records biopsy-proven from First Affiliated Hospital Wenzhou Medical University between Jan 1, 2000 and Dec 31, 2014....
IgA nephropathy is a primary cause of renal failure, and inflammation fibrosis are the main mechanisms leading to kidney damage. The serum fibrinogen level closely related inflammatory states, but its relationship prognosis (IgAN) unclear.1053 patients diagnosed with IgAN after biopsy were enrolled from two Nephrology Departments. Demographic clinical data histopathological features collected. divided into four groups (Q1-Q4) according levels at time biopsy, relationships other risk factors...
Abstract Background Continuous ambulatory peritoneal dialysis (CAPD) patients have a high incidence of stroke and commonly increased parathyroid hormone levels vitamin D insufficiency. We seek to investigate the role supplementation in risk among CAPD patients. Methods This study employed retrospective design. enrolled Chinese cohort 980 who were routinely followed our department. The demographic clinical data recorded at time initial during follow-up. included separated into non-stroke...
This study aimed to investigate the association of antiphospholipid antibodies (aPL) with clinical activity and renal pathological in patients lupus nephritis (LN).Levels anticardiolipin () antibodies, anti-β2-glycoprotein I (anti-β2-GPI) anticoagulant (LAC) were measured, other data also obtained during same period before biopsy.A total 83 LN included this study, 40 (48.2%) s positive group 43 aPL negative group. had significantly higher SLEDAI (p = 0.012), more hematuria 0.043), lower...