A5089610431- Multiple Sclerosis Research Studies
- Family Support in Illness
- Palliative Care and End-of-Life Issues
- Patient-Provider Communication in Healthcare
- Bladder and Urothelial Cancer Treatments
- Childhood Cancer Survivors' Quality of Life
- Health Systems, Economic Evaluations, Quality of Life
- Polyomavirus and related diseases
- Urinary and Genital Oncology Studies
- Soil erosion and sediment transport
- Mycobacterium research and diagnosis
- Family and Disability Support Research
- Amyotrophic Lateral Sclerosis Research
- Prostate Cancer Diagnosis and Treatment
- Patient Dignity and Privacy
- Urologic and reproductive health conditions
- Plant Ecology and Soil Science
- Cystic Fibrosis Research Advances
- Systemic Sclerosis and Related Diseases
- Urological Disorders and Treatments
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Mindfulness and Compassion Interventions
- Tracheal and airway disorders
- Health, Environment, Cognitive Aging
Fondazione IRCCS Istituto Neurologico Carlo Besta
2014-2024
University of Turin
1991-2024
Azienda Ospedaliero Universitaria San Giovanni Battista
2020
Fondazione Ricerca Molinette
2020
Institute for Scientific Interchange
2018
Santa Maria Nuova Hospital
2012
Ospedale San Filippo Neri
2012
Universidad Nacional de La Plata
2008
Università Cattolica del Sacro Cuore
2007
University of Perugia
2004-2005
Peripheral blood expansion of an unusual CD4+ T-cell subset lacking surface CD28 has been suggested to predispose rheumatoid arthritis (RA) patients develop more aggressive disease. However, the potential association between CD4+CD28null T cells and early atherosclerotic changes in RA never investigated.The number circulating was evaluated 87 33 control subjects who also underwent evaluation carotid artery intima-media thickness (IMT) endothelial function via flow-mediated vasodilation...
Background Few data on services for people with severe multiple sclerosis (MS) are available. The Palliative Network Severely Affected Adults MS in Italy (PeNSAMI) developed a home palliative care program patients and carers, preceded by literature review qualitative study (here reported). Objective To identify unmet needs of living at research involving key stakeholders, theorize broad areas intervention to meet those needs. Method Data were collected from: least 10 personal interviews...
Objectives To report 3‐year follow‐up results of the first implantations with a temporary implantable nitinol device ( TIND ® ; Medi‐Tate Ltd., Or Akiva, Israel) for treatment lower urinary tract symptoms LUTS ) secondary to benign prostatic hyperplasia BPH ). Patients and Methods In all, 32 patients were enrolled in this prospective study. The study was approved by local Ethics Committee. Inclusion criteria were: age >50 years, International Prostate Symptom Score IPSS ≥10, peak flow Q...
An Australian case series study demonstrated the effectiveness of REsilience and Activities for every DaY people with multiple sclerosis (READY MS), a resilience group training program based on Acceptance Commitment Therapy, in improving quality life MS. This aimed to evaluate feasibility acceptability Italian READY MS program, preliminary assess its efficacy when compared an active control intervention (group relaxation).Single-blind phase II randomized controlled trial (RCT) nested...
Abstract: This study was designed to compare intima media thickness (IMT) of the carotid arteries among rheumatoid arthritis (RA) patients and controls determine whether disease-associated characteristics, smoking, other classic risk factors for atherosclerosis are associated with IMT values. measured in 101 RA 75 control subjects. The evaluated common (CC), bifurcation (BI), internal (IC). Eight values were calculated including four mean maximal CC, BI, IC, artery (C). following data...
Background: Patients report information deficits in the period surrounding diagnosis of multiple sclerosis (MS). We assessed effectiveness an add-on aid for newly diagnosed MS patients. Methods: randomly assigned 120 patients from five Italian centres to disclosure (current practice at centre) or current plus (ISRCTN81072971). The consisted a personal interview with physician using navigable compact disc and take-home booklet. primary composite endpoint was score highest tertile knowledge...
There are few studies on patient knowledge in multiple sclerosis (MS), and only two published questionnaires. The objective of this article was to develop validate the MS Knowledge Questionnaire (MSKQ), a self-assessed instrument for newly diagnosed patients. Thirty multiple-choice statements, conceived test knowledge, were produced by multidisciplinary panel pre-tested three patients, resulting an intermediate 26-item version. This tested 54 patients internal consistency, content construct...
Background The Control Preference Scale (CPS) is the most frequently used measure of patients' preferred roles in treatment decisions. We revised original CPS and developed a new computerized patient self-administered version (eCPS). eCPS to assess role preferences, their determinants, Italian German people with multiple sclerosis (MS). Methods New cartoons were produced, based on MS health professional input/feedback previous findings, pilot tested 26 patients. acceptability reliability...
To assess decision-making in multiple sclerosis (MS) from third observer and patient perspectives.
Background: Evidence on the efficacy of palliative care in persons with severe multiple sclerosis (MS) is scarce. Objective: To assess a home-based approach (HPA) for adults MS and their carers. Methods: Adults MS-carer dyads were assigned (2:1 ratio) to either HPA or usual (UC). At each center, multi-professional team delivered 6-month intervention. A blind examiner assessed at baseline, 3 months, 6 months. Primary outcome measures Palliative Outcome Scale-Symptoms-MS (POS-S-MS) Schedule...
Background and purpose Patients with severe, progressive multiple sclerosis (MS) have complex physical psychosocial needs, typically over several years. Few treatment options are available to prevent or delay further clinical worsening in this population. The objective was develop an evidence‐based practice guideline for the palliative care of patients MS. Methods This developed using Grading Recommendations Assessment, Development Evaluation methodology. Formulation questions performed...
We tested apnoea/hypopnoea index (AHI), high-sensitivity (hs) C-reactive protein and clinical/instrumental variables as predictors of atrial fibrillation (AF) recurrence over 1-year follow-up after successful electrical cardioversion. enrolled 158 consecutive patients. Apnoea/hypopnoea was assessed with standard overnight polysomnography hs-C-reactive immunonephelometry assay the day before Atrial recurrences occurred in 81 patients (51%). Predictors at univariate analysis were: AHI ≥ 15...
Background Anxiety and depression are common in people with multiple sclerosis (MS), but data on emotional communication during MS consultations lacking. We assessed patient expressions of emotion neurologist responses first-ever using the Verona Coding Definitions Emotional Sequences (VR-CoDES). Methods applied VR-CoDES to recordings/transcripts 88 outpatient (10 neurologists, four Italian centers). Before consultation, patients completed Hospital Depression Scale (HADS). Multilevel...
Background The Multiple Sclerosis Quality of Life-54 (MSQOL-54, 52 items grouped in 12 subscales plus two single items) is the most used MS specific health related quality life inventory. Objective To develop a shortened version MSQOL-54. Methods MSQOL-54 dimensionality and metric properties were investigated by confirmatory factor analysis (CFA) Rasch modelling (Partial Credit Model, PCM) on MSQOL-54s completed 473 patients. Their mean age was 41 years, 65% women, median Expanded Disability...
<h3>Objectives:</h3> To assess the responsiveness of three most used patient reported multiple sclerosis (MS) specific questionnaires: Functional Assessment MS (FAMS), Impact Scale (MSIS-29) and 54 item Quality Life (MSQOL-54). <h3>Design:</h3> Prospective multicentre longitudinal study on 104 patients treated with intravenous steroids for clinical exacerbation. <h3>Methods:</h3> Patient data, Expanded Disability Status (EDSS) score information were collected at admission 8 weeks later....