A5058699032- Multiple Sclerosis Research Studies
- Patient-Provider Communication in Healthcare
- Family Support in Illness
- Palliative Care and End-of-Life Issues
- Hereditary Neurological Disorders
- Peripheral Neuropathies and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Polyomavirus and related diseases
- Childhood Cancer Survivors' Quality of Life
- Epilepsy research and treatment
- Botulinum Toxin and Related Neurological Disorders
- Migraine and Headache Studies
- Genetic Neurodegenerative Diseases
- Family and Disability Support Research
- Glioma Diagnosis and Treatment
- Patient Dignity and Privacy
- COVID-19 and Mental Health
- Powdery Mildew Fungal Diseases
- Mycobacterium research and diagnosis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neurological diseases and metabolism
- Resilience and Mental Health
- Vaccine Coverage and Hesitancy
- Amyotrophic Lateral Sclerosis Research
- Fungal Plant Pathogen Control
Fondazione IRCCS Istituto Neurologico Carlo Besta
2016-2025
The University of Queensland
2020
John Wiley & Sons (United States)
2020
Hudson Institute
2020
The Neurological Institute
2005-2019
Istituti di Ricovero e Cura a Carattere Scientifico
2011
Imperial College London
2006
Bambino Gesù Children's Hospital
2006
University of Messina
2006
Hammersmith Hospital
2006
Abstract The progress of biomedical technologies has expanded the boundaries care, offering new treatment options and prolonging patients’ survival even in conditions great suffering dependence. End-of-life decisions are an important topic contemporay bioethics physician-assisted suicide (PAS) is a still controversial topic, with Neurology at forefront. This glossary provides set definitions to improve clarity use consistent language bioethical debate on autonomy, limitations, palliative...
It is widely agreed that after two or more seizures patients should be given antiepileptic treatment, but there still controversy about the treatment of a first unprovoked seizure. In multicenter, randomized, open trial, with tonic-clonic seizure were randomized to immediate (carbamazepine, phenytoin, phenobarbital, sodium valproate) only another Fifty-two(24%) 215 and 85 (42%) 204 delayed experienced recurrence during follow-up. Age, acute benzodiazepines, remote etiologic factors, EEG...
Although physical rehabilitation is commonly administered to MS patients, its efficacy has not been established.We assessed the of an inpatient program on impairment, disability, and quality life patients with a randomized, single-blind, controlled trial.Fifty ambulatory were assigned 3 weeks (study treatment) or exercises performed at home (control treatment). Patients evaluated baseline 3, 9, 15 by blinded examining physician.No changes in impairment occurred either group, as measured...
The accuracy and precision of chronological age estimation based on the stages third molar tooth development was studied in a sample 679 radiographs from individuals Hispanic origin. range 14.0 to 25.0 years. Eight raters University Texas Health Science Center at Houston Dental Branch evaluated according Demirjian's schematic definitions crown root formation. objective this study evaluate chronology Hispanics following protocol previous study. Within population, rate male is greater than...
To assess the efficacy of phenylbutyrate (PB) in patients with spinal muscular atrophy a randomized, double-blind, placebo-controlled trial involving 10 Italian centers.One hundred seven children were assigned to receive PB (500 mg/kg/day) or matching placebo on an intermittent regimen (7 days on/7 off) for 13 weeks. The Hammersmith functional motor scale (primary outcome measure), myometry, and forced vital capacity assessed at baseline weeks 5 13.Between January September 2004, 107 aged 30...
Background: The safety and efficacy of the oral iron-chelating agent deferiprone on magnetic resonance pallida iron concentration clinical status were investigated in 10 patients affected by pantothenate kinase–associated neurodegeneration. Methods: Nine (age range, 7–39 years) completed study. Results: A significant median reduction globus pallidus content as assessed T2* relaxometry (and calculated R2* maps; P = .008) was observed at end None demonstrated a change Burke-Fahn Marsden...
<h3>OBJECTIVES</h3> Health related quality of life (HRQOL) inventories are multi-dimensional measures patient-centred health status developed for clinical research. The MS 54 (MSQOL-54) is an MS-specific HRQOL inventory originally devised English speaking patients. It consists a core measure, the 36-item short form survey (SF-36) previously adapted into Italian, and 18 additional items exploring domains relevant to patients with (MS-18 module). authors translated culturally Italian MS-18...
Abstract We have assessed the reliability of hand‐held myometry in 33 patients with spinal muscular atrophy (SMA), testing elbow flexion, handgrip, three‐point pinch, knee extension, and foot dorsiflexion, determining intraclass correlation coefficients (ICC). Interrater was high for upper limbs, an ICC 0.92 pinch 0.98 flexion grip. For lower limbs interrater good >0.85 all measures except dorsiflexion. Test–retest results were excellent >0.91 instances. Hand‐held is easily performed...
Background Few data on services for people with severe multiple sclerosis (MS) are available. The Palliative Network Severely Affected Adults MS in Italy (PeNSAMI) developed a home palliative care program patients and carers, preceded by literature review qualitative study (here reported). Objective To identify unmet needs of living at research involving key stakeholders, theorize broad areas intervention to meet those needs. Method Data were collected from: least 10 personal interviews...
While the major phenotypes of multiple sclerosis (MS) and relapsing-remitting, primary secondary progressive MS have been well characterized, a subgroup patients with an active, aggressive disease course rapid disability accumulation remains difficult to define there is no consensus about their management treatment. The current lack accepted definition treatment guidelines for triggered 2018 focused workshop European Committee Treatment Research in Multiple Sclerosis (ECTRIMS) on MS. aim was...
Hereditary neuropathy with liability to pressure palsies (HNPP) is commonly associated a 1.5-megabase deletion on chromosome 17p11.2-12. We analyzed the phenotypic expression of in 39 HNPP patients from 16 families carrying deletion. Two-thirds individuals had episodes acute mononeuropathy, often involving nerve territories upper limbs or brachial plexus; however, 41% affected subjects were unaware their disease, and 25% almost totally free symptoms; one-third complained chronic symptoms...
Studies on communicating the diagnosis of multiple sclerosis (MS) are few, and all reveal communication information deficits. We explored personal experience people with MS health professionals, using a qualitative methodology. Data were obtained from two sets focus group meetings (FGM) (total 23; 16 females; age range: 23-70) one FGMs professionals (four neurologists, three psychologists, nurses). The methods framework analysis applied to meeting transcripts identify key topics categories....