A5042279340- Phytochemical Studies and Bioactivities
- Phytochemistry and Bioactive Compounds
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Edible Oils Quality and Analysis
- Fatty Acid Research and Health
- Gastrointestinal Tumor Research and Treatment
- Sarcoma Diagnosis and Treatment
- Cholesterol and Lipid Metabolism
- Polysaccharides and Plant Cell Walls
- Microbial Metabolites in Food Biotechnology
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Phytochemical and Pharmacological Studies
- Neurofibromatosis and Schwannoma Cases
- Postharvest Quality and Shelf Life Management
- Cynara cardunculus studies
- Food composition and properties
- Adipokines, Inflammation, and Metabolic Diseases
- Ophthalmology and Visual Health Research
- Gastrointestinal disorders and treatments
- Tannin, Tannase and Anticancer Activities
- Polysaccharides Composition and Applications
- Genomics, phytochemicals, and oxidative stress
- Helicobacter pylori-related gastroenterology studies
Instituto de la Grasa
2014-2024
Consejo Superior de Investigaciones Científicas
2008-2022
Universidad Pablo de Olavide
2019
Hospital Universitario Virgen Macarena
2011-2012
Norwich Research Park
2008
Andalusian Institute of Agricultural and Fisheries Research and Training
2008
Three different methods (antiradical activity, inhibition of primary oxidation, and ferric reducing power) have been used to evaluate the antioxidant activity eight asparagus cultivars byproducts: white green from Alcalá del Río (Guadalquivir Valley, Seville) American hybrids, native spears, their byproducts Huétor-Tájar (Vega de Granada). The correlation between total phenol content was studied. Six standards were also tested validate modified for determination. Results obtained antiradical...
The aim of this study was to determine whether isorhamnetin, an immediate 3′-O-methylated metabolite quercetin, affects proliferation, cell death, and the cycle human colon carcinoma (HCT-116) cells. Isorhamnetin found be a potent antiproliferative agent in dose- time-dependent manner, with IC50 72 μM after 48 h incubation as estimated by MTT assay. Flow cytometry fluorescence microscopy analysis showed that isorhamnetin exerted stimulatory effect on apoptosis necrosis. also increased number...
The determination of flavonoid profiles from different genotypes triguero asparagus and their comparison to those green commercial hybrids was the main goal this study. samples consisted 32 65 Huetor-Tajar population variety (triguero). analysis individual flavonoids by HPLC-DAD-MS has allowed eight naturally occurring flavonol derivatives in several asparagus. Those compounds included mono-, di-, triglycosides three flavonols, that is, quercetin, isorhamnetin, kaempferol. detailed revealed...
Novel biological activities for tyrosol metabolites on human endothelial cells.
Olive oil and its derivatives have been described to exert beneficial effects on hypertensive states cardiovascular disease prevention. We studied the of chronic consumption extra virgin olive (EVOO), enriched in bioactive compounds from fruit leaves, blood pressure, endothelial function, oxidative inflammatory status, circulating cholesterol levels, spontaneously rats (SHR). Thirty SHR were randomly assigned three groups: a control untreated group, an group (1 mL/rat/day) (17.6 mg/kg...
In this study, Asparagus stipularis was characterized concerning its phytochemical composition, antioxidant potential, cytotoxicity, and pancreatic lipase inhibitory activities. Twenty-seven compounds were identified quantified by HPLC-DAD-MS in the leaf, stem, pericarp, rhizome of ethanolic extracts. Seven steroidal saponins detected, highest content pericap. A. also contained significant amounts flavonoids aerial part. Isorhamnetin tetra-glycoside, quercetin-3-glucosyl-rutinoside, rutin...
The main goal of this study was the optimization a HPLC-MS method for qualitative and quantitative analysis asparagus saponins. includes extraction with aqueous ethanol, cleanup by solid phase extraction, separation reverse chromatography, electrospray ionization, detection in single quadrupole mass analyzer. used comparison selected genotypes Huétor-Tájar landrace varieties commercial diploid hybrids green asparagus. results showed that while protodioscin almost only saponin detected...
The phytochemical composition of leaves, stems, pericarps and rhizomes ethanolic extracts
Abstract The aim of this work was to study the saponin profiles from spears different wild asparagus species in context its genetic diversity aside geographical seed origin. They included Asparagus pseudoscaber Grecescu, maritimus (L.) Mill., brachiphyllus Turcz., prostrates Dumort., and officinalis L. analysis by LC‐MS has shown that profile is similar previously described for triguero Huétor‐Tájar landrace ( HT), which had not ever been reported edible part asparagus. All samples, except A...
Abstract White asparagus cell walls have shown to contain important amounts of phenolics, including ferulic acid and its dimers trimers. It has been suggested that these phenolic compounds are mainly responsible for cross‐linking the different wall polymers related hardening. During post‐harvest storage, texture amount phenolics increased significantly. In present work, effect storage conditions on accumulation derivatives investigated. Three were used: keeping spears in aerobic at room...
The presence of 3,4-dihydroxyphenylglycol (DHPG) was studied in 32 samples and 10 different cultivars natural table olives, using an accurate method to avoid wrong quantification. Hydroxytyrosol (HT), tyrosol, verbascoside were also quantified, as these four compounds comprise the majority chromatographic profile. Analyses carried out by HPLC-DAD-UV after extraction all phenolics, hydroxytyrosol major component nearly samples. High levels DHPG (up 368 mg/kg dry weight) found pulp black...
The main goal of this study was to determine the saponin profiles different "triguero" asparagus genotypes and compare them green commercial hybrids. samples consisted 31 hybrids 58 from Huétor-Tájar (HT) population variety ("triguero"). analysis by high-performance liquid chromatography-mass spectrometry allowed for determination 12 saponins derived a furostan-type steroidal genin, 4 which had never been described in edible part asparagus. profile combination these new protodioscin....
Abstract The changes of texture that take place in white and green asparagus during storage cooking are, large part, determined by the composition structure cell walls. Several instrumental methods have been applied to three sections spears investigate physico‐chemical properties contribute values texture. Cutting with a razor blade is most appropriate method for quantifying comparing and, among different parameters can be calculated from curves registered cutting, strength toughness used...
Abstract Cinnamic acids influence physical and textural attributes of plant foods as they play an important role in lignification cross‐linking cell‐wall polymers. Several trans ‐cinnamic have been detected asparagus cell wall (CW), and, these, amounts ferulic acid (FA) its dehydrodimers found to increase significantly during post‐harvest storage. The distribution these compounds along the different sections white green spears, well their modifications postharvest storage, has investigated....