Clayton J. Brinster

ORCID: 0000-0003-4469-2558
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About
Contact & Profiles
Research Areas
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic Disease and Treatment Approaches
  • Cerebrovascular and Carotid Artery Diseases
  • Vascular Procedures and Complications
  • COVID-19 and healthcare impacts
  • Cardiovascular Health and Disease Prevention
  • Renal and Vascular Pathologies
  • Acute Ischemic Stroke Management
  • Infectious Aortic and Vascular Conditions
  • Reproductive Biology and Fertility
  • Sperm and Testicular Function
  • Congenital Heart Disease Studies
  • Cardiac Valve Diseases and Treatments
  • Healthcare Policy and Management
  • COVID-19 Clinical Research Studies
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular anomalies and interventions
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Infective Endocarditis Diagnosis and Management
  • Peripheral Artery Disease Management
  • Frailty in Older Adults
  • Climate Change and Health Impacts
  • Cardiac and Coronary Surgery Techniques
  • Peripheral Neuropathies and Disorders

Ochsner Health System
2021-2024

University of Chicago
2024

Ochsner Medical Center
2016-2023

University of New Orleans
2022

Paracelsus Medizinische Privatuniversität
2015

Massachusetts General Hospital
2015

Harvard University
2014

University of Pennsylvania
1996-2012

Hospital of the University of Pennsylvania
2009-2011

Royal Victoria Hospital
2001

The proliferation and differentiation of a stem cell are regulated intrinsically by the extrinsically niche. Elucidation regulatory mechanisms spermatogonial cells (SSCs), postnatal male germ line, would be facilitated in vitro studies that provide defined microenvironment reconstituted ex vivo. We analyzed effect environment on maintenance adult immature SSCs 7-day culture system. Allthough number decreased time-dependent manner, nearly one four (24%) could maintained for 7 days. Stem was...

10.1095/biolreprod.102.014050 article EN Biology of Reproduction 2003-06-01

Male germ-line stem cells are the only cell type in postnatal mammals that have capability to self-renew and contribute genes next generation. Genetic modification of these would provide an opportunity study biology their complex self-renewal differentiation processes, as well enable generation transgenic animals a wide range species. Although retroviral vectors been used efficient method introduce into variety types, male seemed refractory direct infection by viruses. In addition,...

10.1073/pnas.231473498 article EN Proceedings of the National Academy of Sciences 2001-10-23

Spermatogenesis occurs within the seminiferous tubules of mammals by a complex process that is highly organized, extremely efficient and very productive. At foundation this spermatogonial stem cell capable both self-renewal production progeny cells, which undergo differentiation over period weeks to months in order generate mature spermatozoa. It had been thought germ cells survive only brief culture, generally less than few weeks. However, an accurate assessment presence any population has...

10.1016/s0040-8166(98)80053-0 article EN cc-by-nc-nd Tissue and Cell 1998-08-01

Spermatogonial transplantation provides access to the mammalian germline and has been used in experimental animal models study stem cell/niche biology development, restore fertility, produce transgenic models. The potential manipulate and/or transplant numerous practical applications that transcend species boundaries. To make technology more broadly accessible, it is necessary develop recipient preparation protocols. In current study, mouse recipients for spermatogonial were prepared by...

10.1095/biolreprod.103.016519 article EN Biology of Reproduction 2003-08-01

To present retrograde target vessel catheterization as a bailout technique in fenestrated and branched endografting (F/B-EVAR).Between November 2003 2014, 11 (1.6%) of 671 consecutive patients with juxtarenal, suprarenal, thoracoabdominal aortic aneurysms required access measure during F/B-EVAR due to failure an antegrade approach. The vessels involved the left renal artery (LRA) 6 patients, celiac (CA) 3 right (RRA) 1 patient, both arteries patient.The were successfully catheterized secured...

10.1177/1526602815592205 article EN Journal of Endovascular Therapy 2015-06-19
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