A5100638933- Drug Solubulity and Delivery Systems
- Nigella sativa pharmacological applications
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Antibiotics Pharmacokinetics and Efficacy
- Protein purification and stability
- Complementary and Alternative Medicine Studies
- Analytical Chemistry and Chromatography
- Biofield Effects and Biophysics
- Hepatitis C virus research
University of Dhaka
2010-2023
The current study aimed at developing and optimizing a prompt, simple efficient RP-UHPLC method based on Quality by Design (QbD) for analyzing mesalamine. Experimental design the was performed capitalizing 32 full factorial in Expert® software (Version 12, Stat-Ease Inc., USA) where percentage of methanol mobile phase flow rate were considered as independent factors studied three levels. Retention time, tailing factor theoretical plate count recorded responses to experiment. Mesalamine...
The aim of this study is to develop a once-daily extended release matrix tablet Niacin using Hydroxy Propyl Methyl Cellulose i.e.Methocel K4M CR as controlling factor and evaluate drug parameters per various kinetic models also find the best fitted formulation Niacin.In order achieve required profile, tablets were prepared by wet granulation technique different formulations (F-1, F-2, F-3, F-4, F-5 F-6) with amount Methocel CR.The formulated characterized physical chemical results found in...
Ledipasvir, belonging to the BCS class II, is a directly acting anti-viral agent used treat Hepatitis C virus infections. Due poor water solubility and oral bioavailability, developing an effective delivery system for this drug has been enormously challenging issue formulators. Moreover, suitable dosage forms pediatric geriatric patients having difficulty in swallowing as well pose added burden. Therefore, present study aims formulate nanosuspension, via solid dispersion technique, based on...