Md. Asaduzzaman

ORCID: 0000-0002-4043-8045
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About
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Research Areas
  • Natural Antidiabetic Agents Studies
  • Urological Disorders and Treatments
  • Cholinesterase and Neurodegenerative Diseases
  • Analytical Methods in Pharmaceuticals
  • Advanced Drug Delivery Systems
  • Nigella sativa pharmacological applications
  • Thyroid Disorders and Treatments
  • Phytochemistry and Bioactivity Studies
  • Diabetes and associated disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Genital Health and Disease
  • Genetic factors in colorectal cancer
  • Diabetes Management and Research
  • Chronic Kidney Disease and Diabetes
  • Nanoparticle-Based Drug Delivery
  • Medicinal Plants and Bioactive Compounds
  • Mycobacterium research and diagnosis
  • Pharmaceutical Practices and Patient Outcomes
  • Vitamin D Research Studies
  • Ear Surgery and Otitis Media
  • Urologic and reproductive health conditions
  • Diabetes Treatment and Management
  • Drug Solubulity and Delivery Systems
  • Oral and Craniofacial Lesions
  • Phytochemistry and Biological Activities

Institute of Child and Mother Health
2024

Shaheed Suhrawardy Medical College
2021-2024

National Institute of Cardiovascular Diseases
2024

Dhaka Medical College and Hospital
2020-2023

University of Asia Pacific
2013-2023

Children's Specialized Hospital
2022

Mymensingh Medical College Hospital
2020-2022

National Institute of Traumatology & Orthopaedic Rehabilitation
2021

Dinajpur Medical College
2020

Kansai University
2020

Neurodegenerative diseases are incurable and debilitating conditions that result in the progressive degeneration of nerve cells, which affect cognitive activity. Currently, as a multiple studies linking Alzheimer's disease (AD) to oxidative damage, uses natural antioxidant prevent, delay, or enhance pathological changes underlying progression AD has received considerable attention. Therefore, this study was aimed at examining effect ethanolic extracts Phyllanthus emblica (EEPE) ripe (EEPEr)...

10.1159/000449482 article EN Annals of Neurosciences 2016-01-01

Nature is the best source of complementary and alternative medicine. The plant Phyllanthus acidus (PA) L. has been used traditionally in pain, inflammatory oxidative stress related disorders. In this consequence, methanolic extract PA (MEPA) was selected to explore ability enhance cognitive function, brain antioxidant enzymes anti-acetylcholinesterase activity which can be for treatment disorders like Alzheimer's disease (AD). purpose study investigate neuroprotective effect MEPA on learning...

10.4236/aad.2016.52005 article EN Advances in Alzheimer s Disease 2016-01-01

Abstract Introduction Diabetes distress (DD) is common and has considerable impacts on diabetes management. Unfortunately, DD less discussed frequently underestimated. This study evaluated the prevalence predictors of in adults with type 2 mellitus (T2DM). Methods A cross-sectional was conducted at several specialized endocrinology outpatient clinics Bangladesh from July 2019 to June 2020; 259 T2DM participated. Participants’ depression were measured using 17-item Distress Scale (DDS-17)...

10.1186/s12902-022-00938-3 article EN cc-by BMC Endocrine Disorders 2022-01-23

Alzheimer's disease (AD) is a progressive neurodegenerative disorder clinically characterized by loss of memory and cognition. Cholinergic deficit oxidative stress have been implicated in the pathogenesis AD. Therefore, inhibition acetylcholinesterase oxidation are two promising strategies development drug for Phyllanthus acidus, belonging to family Euphorbiaceae, tree has used traditional medicine treat several pain, inflammatory related disorders such as rheumatism, bronchitis, asthma,...

10.1186/s12906-015-0930-y article EN cc-by BMC Complementary and Alternative Medicine 2015-11-09

Background: Neurological disorders represent one of the most prominent causes morbidity and mortality that adversely affect lifestyle patients a major percentage these diseases exists in developing countries. Purpose: The objective this study was to examine prevalence prescription pattern for outpatients with neurological Bangladesh. Methods: conducted on 1,684 6 hospitals (National Institute Neurosciences Hospital, Dhaka Medical College Bangabandhu Sheikh Mujib University, Shaheed...

10.1159/000481812 article EN Annals of Neurosciences 2017-10-31

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas pharmaceutical Science including drugs, community pharmacy, hospital clinical compounding consultant internet veterinary nuclear military pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics,...

10.9734/bjpr/2016/22044 article EN British Journal of Pharmaceutical Research 2015-11-14

Background: Oxidative stress is strongly linked in the development of numerous chronic and degenerative disorders. Medicinal plants with antioxidant anticholinesterase activities exert a key role for management oxidative related disorders mainly Alzheimer's disease (AD). Therefore purpose this study was to assess potentiality inhibitory activity crude methanolic extract (CME), petroleum ether fraction (PEF), chloroform (CLF), ethyl acetate (EAF) aqueous (AQF) Uvaria littoralis (U....

10.6000/2292-2598.2017.05.02.3 article EN Journal of Intellectual Disability - Diagnosis and Treatment 2017-07-19

Diabetes mellitus (DM) is the most common metabolic disease worldwide. Multiple medications and side effects, significant prevalent themes in diabetes ultimately determine novel directions avenues drug discovery. The objective of this study was to effects NS (Nigella sativa) L. Seed hydroalcholic Extract on hypoglycemic hypolipidemic condition Streptozotocin- induced diabetic rats. DM by single intraperitoneal injection freshly prepared Streptozotocin (STZ) (65 mg/kg body weight) solution....

10.4172/2329-9029.1000158 article EN Journal of Plant Biochemistry & Physiology 2015-01-01

Objectives: In case of Bangladeshi population, no report is observed till now showing the genetic variations RAD51 (rs1801320) and XRCC2 (rs3218536) genes polymorphism having association with colorectal cancer risk. For this reason aim study to ascertain their interrelation occurrence in population. Materials Methods: A control was conducted where 200 patients healthy volunteers were figured for research using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP)....

10.31557/apjcp.2020.21.5.1445 article EN cc-by Asian Pacific Journal of Cancer Prevention 2020-05-01

Worldwide prevalence of diabetes mellitus has become an issue great concern in current decades. This life threatening disease is associated with worsening glycemic control and progressive metabolic dysfunctions. Objective: Current study aimed to investigate the effect hydroxychloroquine (HCQ) as adjunct glibenclamide or metformin on alloxan induced diabetic rats. Methods: HCQ was combined separately two conventional anti-diabetic drugs; metformin. At first, (120 mg/kg) rats were treated...

10.4236/pp.2014.57082 article EN cc-by Pharmacology &amp Pharmacy 2014-01-01

Background: Road traffic accidents (RTAs) are a significant public health issue globally, particularly in developing countries like Bangladesh. This study focuses on the epidemiological and clinical aspects of upper limb fractures resulting from RTAs, with an emphasis treatment modalities employed. Methods: retrospective observational analyzed hospital records 40 patients due to RTAs at Chakaria Unique Hospital, Cox’s Bazar, Bangladesh, within period 1 year, February 2023 January 2024. The...

10.18203/issn.2455-4510.intjresorthop20241699 article EN International Journal of Research in Orthopaedics 2024-06-26

Aims: To know how much knowledge and awareness university students of Bangladesh have about commonly used medicines. Study Design: The study was conducted on 1200 randomly selected from 9 Bangladesh, in which 87.5% were master’s student remaining 12.5% honor’s students. Each willing participant shared their opinion. Place Duration Study: Dhaka University (DU), Jahangirnagar (JU), Eastern (EU), East West (EWU), Daffodil International (DIU), North South (NSU), Islamic Chittagong (IIUC),...

10.9734/bjmmr/2016/24364 article EN British Journal of Medicine and Medical Research 2016-01-10

Insulin pen devices and disposable plastic insulin syringes are two common tools for administration. This study aims to compare the simplicity, convenience, safety, cost-effectiveness of pens versus syringe in patients with type 2 diabetes mellitus (T2DM).A cross-sectional was conducted at 14 clinics throughout Bangladesh from November 2021 April 2022 among adults T2DM injecting by or least once a day one year purposive sampling. The safety were assessed using structured questionnaire,...

10.1186/s12902-023-01292-8 article EN cc-by BMC Endocrine Disorders 2023-02-13

The aim of the current study is to investigate effect combination glibenclamide; an antidiabetic drug and simvastatin; a HMG-CoA reductase inhibitor on long-term (four weeks) alloxan-induced diabetes rats (ADRs). Methods: Alloxan (120 mg/kg body weight, BW) was injected intra-peritonially (i.p.) in rats. At first alloxan induced diabetic were treated with single dose glibenclamide (1.2 mg/70kg simvastatin (10 for two weeks. Then fixed combinations (0.6 (5 along those drugs four Results: it...

10.4236/pp.2014.511115 article EN cc-by Pharmacology &amp Pharmacy 2014-01-01

Background: The roles of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte (PLR) as novel surrogate markers diabetic kidney disease (DKD) are promising. Objective: aim this study was to evaluate whether NLR PLR can predict DKD in type 2 diabetes mellitus (T2DM). Subjects Methods: This cross-sectional conducted from July 2018 June 2019, among 312 patients with T2DM recruited eight tertiary hospitals throughout Bangladesh. Complete blood count (CBC) performed fully automated hematology...

10.4103/jod.jod_4_20 article EN Journal of Diabetology 2021-01-01

This study was aimed to evaluate the efficacy of Honey, Coccinia cordifolia (Locally known as Telakucha) leaves and Hilsha fish oil hypoglycemic hypolipedemic agents in diabetic condition. The were initially under shade, grinded powder, extracted with ethanol filtered through Whatmann filter paper. filtrate concentrated by rotatory evaporator stored at 4°C. experimental rats divided into six groups (n=6). Diabetes mellitus (DM) induced single intraperitoneal injection (65 mg/kg BW) freshly...

10.4172/0974-8369.1000272 article EN cc-by Biology and Medicine 2015-01-01
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