Mohammad Safiqul Islam

ORCID: 0000-0003-4924-5319
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About
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Research Areas
  • Genetics and Neurodevelopmental Disorders
  • Trace Elements in Health
  • Autism Spectrum Disorder Research
  • Pharmacogenetics and Drug Metabolism
  • Vitamin C and Antioxidants Research
  • Cancer-related molecular mechanisms research
  • COVID-19 Clinical Research Studies
  • Glutathione Transferases and Polymorphisms
  • Genetic factors in colorectal cancer
  • DNA Repair Mechanisms
  • Diabetes Treatment and Management
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • Analytical Methods in Pharmaceuticals
  • RNA modifications and cancer
  • Tryptophan and brain disorders
  • Heavy Metal Exposure and Toxicity
  • Folate and B Vitamins Research
  • Cancer-related Molecular Pathways
  • Cervical Cancer and HPV Research
  • Pregnancy and preeclampsia studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Drug Transport and Resistance Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Inflammatory mediators and NSAID effects

Noakhali Science and Technology University
2016-2025

Research Manitoba
2024

Jahangirnagar University
2020-2021

Shimane University
2014-2020

University of Chittagong
2018

University of Rajshahi
2017

University of Dhaka
1970-2015

North South University
2015

Czech Academy of Sciences, Institute of Physiology
2015

University of Shimane
2014

Natural compounds hold promise in the search for cancer therapies due to their unique chemical structures and combinations that may effectively combat while minimizing toxicity side effects compared conventional treatments. Silibinin, a natural lignan, has been found possess strong anti-cancer activity against several types of human cancers based on emerging research. This study aims provide an overview therapeutic potential silibinin treatment prevention cancers. A comprehensive was...

10.3389/fphar.2024.1349745 article EN cc-by Frontiers in Pharmacology 2024-02-29

Major depressive disorder (MDD) is a mixed with the highly irregular course, inconsistent response to treatment and has no well-known mechanism for pathophysiology. causes of depression are genetic, neurobiological, environmental. However, over past few years, altered serum levels macro-minerals (MM) trace elements (TE) have been recognized as major causative factors pathogenesis many mental disorders. The purpose this study was determine MM (calcium magnesium) TE (copper, iron, manganese,...

10.1186/s12888-018-1685-z article EN cc-by BMC Psychiatry 2018-04-10

The dengue virus is widespread throughout Bangladesh and significantly contributes to morbidity mortality. One effective method for preventing further epidemics reduce mosquito breeding at the most opportune period each year. This study aims determine prevalence in 2022 by comparing previous years' data estimating of this disease's significant incidence.

10.1002/hsr2.1210 article EN cc-by-nc Health Science Reports 2023-04-01

The study was conducted to evaluate the in vitro thrombolytic activity, and vivo analgesic, anti-inflammatory antipyretic potentials of different hydrocarbon soluble extracts Litsea glutinosa leaves for first time widely used folkloric treatments Bangladesh. This work aimed create new insights on fundamental mechanisms plant involved these activities.In activity assay, a significant clot disruption observed at dose 1 mg/mL each (volume 100 μL) when compared standard drug streptokinase....

10.1186/0717-6287-47-56 article EN cc-by Biological Research 2014-10-29

Major depressive disorder is diagnosed on the basis of patient's self-reported experiences, behavior reported by relatives, and a mental status examination, yet we do not have any reliable biomarker for this. Mood-regulating pathways are affected oxidative injury to lipids cortisol released into blood due stimulation corticotrophin receptors in adrenal cortex. Here, aimed determine serum levels malondialdehyde major patients controls.We collected samples from 247 248 controls. Serum were...

10.1177/2050312118773953 article EN cc-by-nc SAGE Open Medicine 2018-01-01

Abstract Background The alterations of biological markers are thought to be effective tools understand the pathophysiology and management major depressive disorder (MDD). A lot researches has implied many for depression, but any them fully discovered association between depression. present study investigated serum levels amino acids non-enzymatic antioxidants in also explained their with Methods This examined 247 MDD patients 248 healthy controls (HCs) matched by age sex. Hamilton Depression...

10.1186/s12888-020-02738-2 article EN cc-by BMC Psychiatry 2020-06-24

Objectives: Disruption in the natural immune reaction due to SARS-CoV-2 infection can initiate a potent cytokine storm among COVID-19 patients. An elevated level of IL-6 and IL-10 during hyperinflammatory state plays vital role increasing risk severity mortality. In this study, we aimed evaluate potential circulating levels as biomarkers for detecting mortality COVID-19. Methods: This study was conducted according Cochrane Handbook PRISMA guidelines. Authorized databases were searched...

10.1177/11772719221106600 article EN cc-by-nc Biomarker Insights 2022-01-01

The present study was designed to investigate the phytochemical screening, free radical scavenging activity and determine total phenolic content of methanolic extract different solvent soluble fractions Averrhoa bilimbi Linn. (Oxalidiaceae) fruits. evaluated by analyzing bleaching rate 1,1-diphenyl-2-picrylhydrazyl (DPPH), determined using Folin-Ciocalteau reagent, which results were expressed in gallic acid equivalent (mg GAE/g sample). screening revealed potent source constituents on...

10.3329/icpj.v2i4.14058 article EN cc-by-nd International Current Pharmaceutical Journal 2013-03-05

Background Epidemiological research suggests that altered levels of cytokine are associated with pathophysiology and the development major depressive disorder (MDD). Based on earlier study, IL-1β rs16944 rs1143627 polymorphisms may increase risk depression. Here, we aimed to evaluate correlation between these MDD susceptibility among population in Bangladesh. Methods Blood samples were collected from 100 patients 70 matched controls. Study participants evaluated by DSM-5 criteria PCR-RFLP...

10.1371/journal.pone.0317665 article EN cc-by PLoS ONE 2025-01-22
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