James Regun Karmoker

ORCID: 0000-0003-0938-9078
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About
Contact & Profiles
Research Areas
  • Pharmaceutical Quality and Counterfeiting
  • Drug Solubulity and Delivery Systems
  • Pharmaceutical Economics and Policy
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Retinal Diseases and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Surfactants and Colloidal Systems
  • Venomous Animal Envenomation and Studies
  • Redox biology and oxidative stress
  • Bioactive Natural Diterpenoids Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Rabies epidemiology and control
  • Treatment of Major Depression
  • Glaucoma and retinal disorders
  • Intensive Care Unit Cognitive Disorders
  • Identification and Quantification in Food
  • Biosimilars and Bioanalytical Methods
  • Nitric Oxide and Endothelin Effects
  • Bipolar Disorder and Treatment
  • Retinoids in leukemia and cellular processes

University of Oklahoma Health Sciences Center
2021-2024

University of Asia Pacific
2015-2022

University of Oklahoma
2021

Abstract Background The alterations of biological markers are thought to be effective tools understand the pathophysiology and management major depressive disorder (MDD). A lot researches has implied many for depression, but any them fully discovered association between depression. present study investigated serum levels amino acids non-enzymatic antioxidants in also explained their with Methods This examined 247 MDD patients 248 healthy controls (HCs) matched by age sex. Hamilton Depression...

10.1186/s12888-020-02738-2 article EN cc-by BMC Psychiatry 2020-06-24

The grail of the study was to design, develop and characterize sustained release mucoadhesive microspheres acyclovir optimize drug profile using response surface methodology by applying Box–Behnken design (BBD) which equipped with three levels factors. Microspheres were prepared from Methocel K15M Ethocel Standard 45 Premium emulsification solvent evaporation technique. independent factors amounts (X1), amount (X2), RPM (X3). dependent variables cumulative percentage (CDR) at 8 hour (Y1),...

10.3329/dujps.v18i1.41421 article EN Dhaka University Journal of Pharmaceutical Sciences 2019-05-16

Background Major depressive disorder (MDD) is a disabling health problem with very high global prevalence and burden. Alteration of inflammatory markers in depression growing interest to many psychiatry researchers. This study aimed examine the serum levels interleukin-6 (IL-6) C-reactive protein (CRP) MDD patients find out their association depression. Materials methods The present recruited 88 86 control subjects matched by age, gender, body mass index (BMI). Hamilton rating scale (Ham-D)...

10.7759/cureus.3868 article EN Cureus 2019-01-11

Injuries to the retinal pigment epithelium (RPE) and outer retina often result in accumulation of microglia within subretinal space. These play crucial roles inflammation resolution, but mechanisms governing their functions are still largely unknown. Our previous research highlighted protective choroidal γδ T cells response RPE injury. In current study, we employed single-cell RNA sequencing approach characterize profiles immune mouse choroid. We found that were primary producer...

10.1073/pnas.2311647120 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2023-12-12

Snakebites are common in tropical countries like Bangladesh where most snakebite victims dwell rural areas. Among the management options after Bangladesh, snake charmers ( Ozha Bengali language) first contact following a for more than 80% of and they treated mostly with help some medicinal plants. Our aim study is to compile plants used treatment occurrence Bangladesh. The field survey was carried out period almost 3 years. Fieldwork undertaken Chittagong Hill Tracts, including Chittagong,...

10.1155/2015/871675 article EN Evidence-based Complementary and Alternative Medicine 2015-01-01

Abstract Comprehensive data are needed to prevent substandard and falsified (SF) medicines as they pose a major risk human health. To assess the quality of selected medicines, samples were collected from random private drug outlets Dhaka North South City Corporation, Bangladesh. Sample analysis included visual observation packaging, authenticity samples, legitimacy registration verification manufacturer, physicochemical analysis, price. Chemical was performed using portable Raman...

10.1038/s41598-021-04309-1 article EN cc-by Scientific Reports 2022-01-07

Background: Major Depressive Disorder (MDD) is a mental disorder characterized by pervasive and persistent low mood which accompanied self-esteem loss of interest or pleasure in day to activities that adversely affects person’s family, work, personal life. There no sufficient laboratory test for the diagnosis MDD it expected this investigation may be helpful better management MDD. We aimed measure serum immunoglobulin levels patients control subjects meet above demand. Methods: For purpose,...

10.4236/health.2018.109090 article EN Health 2018-01-01

In this present investigation, gastroretentive mucoadhesive microspheres of Repaglinide was formulated, characterized and optimized by applying the design experiment (DoE) for better release profile sustain action drug. Solvent evaporation technique used to prepare microspheres, where Methocel K15M CR (X1), Eudragit L 100 (X2) rpm (X3) were as independent variables whereas percent cumulative drug at 8 hours (Y1), bond strength (Y2) swelling (Y3) dependent variables. Particle size, surface...

10.3329/bpj.v22i2.42297 article EN Bangladesh Pharmaceutical Journal 2019-07-21

Abstract Comprehensive data are needed to prevent substandard and falsified (SF) medicines as they pose a major risk human health. To assess the quality of select medicines, samples were collected from random private drug outlets Dhaka North South City Corporation, Bangladesh. Sample analysis included visual observation packaging, authenticity samples, legitimacy registration verification manufacturer, physicochemical analysis, price. Chemical was performed using portable Raman spectroscopy...

10.21203/rs.3.rs-240086/v1 preprint EN cc-by-nc-sa Research Square (Research Square) 2021-03-17
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