A5016197304- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Sirtuins and Resveratrol in Medicine
- Essential Oils and Antimicrobial Activity
- Medicinal Plants and Neuroprotection
- Phytochemicals and Medicinal Plants
- Liver Disease Diagnosis and Treatment
- Ethnobotanical and Medicinal Plants Studies
- Natural product bioactivities and synthesis
- Nuclear Structure and Function
- Biochemical effects in animals
- Free Radicals and Antioxidants
- Plant-Derived Bioactive Compounds
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Bioactive Compounds
- Vitamin C and Antioxidants Research
- Moringa oleifera research and applications
- Curcumin's Biomedical Applications
- Viral Infections and Immunology Research
- Plant biochemistry and biosynthesis
- Vitamin D Research Studies
- Obesity, Physical Activity, Diet
- Drug-Induced Hepatotoxicity and Protection
BRAC University
2015-2025
Mymensingh Medical College Hospital
2017-2022
University of Dhaka
2021
Griffith University
2013-2016
Stamford University Bangladesh
1970-2014
In the present study, antioxidant potential of methanol extract leaves Mimusops elengi Linn. was evaluated by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, reducing power and total capacity. The showed significant activities in all assays compared to reference ascorbic acid a dose dependent manner. DPPH assay IC50 value found be 43.26μg/ml while standard 58.92 μg/ml. Total activity also increase Moreover, M. strong power. These results suggest that may act as...
Hydromethanol extracts of fifteen Bangladeshi medicinal plants, traditionally used in different ailments, were evaluated for antioxidant potential using DPPH (1,1-diphenyl-2-picryl hydrazyl) radical scavenging assay. Among the extractsCocos nucifera, Caesalpinia pulcherrima, Punica granatum and Syzygium cumini were found displaying strong (90% or more) action. Syzygium cumini exhibited highest scavenging, with an IC50value 4.25 μg/ml compared to IC50 value 5.15 as shown by reference ascorbic...
Antioxidant activity of the methanol extract Ixora coccinea L. was determined by DPPH free radical scavenging assay, reducing power and total antioxidant capacity using phosphomolybdenum method. Preliminary phytochemical screening revealed that flower I. possesses flavonoids, steroids tannin materials. The showed significant activities in all assays compared to standard a dose-dependent manner remarkable scavenge reactive oxygen species (ROS) may be attributed high amount hydrophilic...
Gardenia jasminoides is a traditional medicinal plant rich in anti-inflammatory flavonoids and phenolic compounds used for the treatment of inflammatory diseases pain. In this present study, antioxidant potential leaves extract was evaluated by using various assays.Various assays such as 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay, reducing power total capacity expressed equivalent to ascorbic acid were employed. Moreover, detected high-performance liquid chromatography...
Problem statement: Mikania scandens (L.) Willd., a medicinal plant, is popularly used as herbal remedy for various ailments in Bangladesh. But the scientific basis its use especially pain and inflammation remains unknown. Therefore, present study was designed to evaluate analgesic antioxidant potential of hydromethanol extract leaves plant. Approach: The activity determined central peripheral pharmacological actions using hotplate tail immersion method acetic acid-induced writhing test mice...
Background Epidemiological research suggests that altered levels of cytokine are associated with pathophysiology and the development major depressive disorder (MDD). Based on earlier study, IL-1β rs16944 rs1143627 polymorphisms may increase risk depression. Here, we aimed to evaluate correlation between these MDD susceptibility among population in Bangladesh. Methods Blood samples were collected from 100 patients 70 matched controls. Study participants evaluated by DSM-5 criteria PCR-RFLP...
The current study sought to determine the pharmacological characteristics of crude methanolic extract (MPF) Pandanus fascicularis Lam. root and its soluble ethyl acetate (EAPF) chloroform (CPF) fractions through in vivo vitro approaches. This herb has been used for generations Bangladesh heal a variety human diseases. Qualitative phytochemical tests confirmed presence alkaloid, glycoside, flavonoid, tannin, resin etc. CPF exhibited highest antioxidative potential DPPH (2, 2-Diphenyl -1-...
Age-related bone loss is associated with changes in cellularity, which include marrow fat infiltration and decreasing levels of osteoblastogenesis. The mechanisms that explain these remain unclear. Although nuclear lamina alterations occur premature aging syndromes body severe osteoporosis, the role proteins age-related remains unknown. Using Zmpste24-null progeroid mice (Zmpste24−/−), exhibit defects accumulate unprocessed prelamin A, we identified several cellularity vivo. We found...
The study was conducted to find out the effect of different levels Centella (Thankuni) leaf (Centella asiatica) extracts on chicken meatballs. Chicken meatballs sample were divided into four treatments viz. 0, 1, 2 and 3% group as T0 , T1 T2 T3, respectively. Days intervals 15, 30 45 days. A 4×4 factorial experiment in completely randomized design having three replications per treatment used for data analyses. Samples preserved at -20˚C Sensory, proximate, physicochemical, biochemical...
Resveratrol is a polyphenolic compound that possesses strong antioxidant and anti-inflammatory activities. This study evaluated the effects of resveratrol on oxidative stress, fibrosis multiple genes regulation in kidneys high fat (HF) diet-fed rats.Wistar rats were fed with HF diet for eight weeks. These also treated Finally, kidney tissue samples isolated from all sacrificed rats. The histological changes, creatinine uric acid levels, stress parameters such as malondialdehyde (MDA), nitric...
The antidiarrhoeal property of the hydroethanolic extract flowering tops Anthocephalus cadamba was assessed on experimental animals. dry (250-500 mg/kg body mass, p.o.) exhibited a dose-dependent decrease in total number faecal droppings castor oil-induced diarrhoea mice. also produced significant (p < 0.01) and reduction intestinal fluids accumulation gastrointestinal transit from 64.59 % 71.19% at doses 250 500 mg/kg. rates were 37.85% 74.91%, respectively, with control standard drug group.
PURPOSE: Blumea lacera (B. lacera) (Asteraceae) is a well-known Bangladeshi medicinal plant. This study aimed to identify and characterize constituents associated with the significant cytotoxic activity of this plant that we reported previously. Here, describe isolation characterization new steroidal glycoalkaloid (SGA) 1, evaluation its activity, apoptotic potential, effect on cell cycle in comparison analogous glycoalkaloids (SGAs). METHODS: SGA 1 was isolated using C18 SPE HPLC,...
In the present study, antioxidant and analgesic potential of 80% methanol extract leaves Curcuma alismatifolia Gangnep was evaluated. The investigated for its activity using lipid peroxidation, total capacity reducing power assays. showed significant activities in peroxidation assay compared to standard a dose dependent manner. assay, IC50 value found be 122.43μg/mL while reference ascorbic acid 147.87μg/ml. Moreover, strong good power. evaluated central peripheral pharmacological actions...
Triphala is a famous triherbal drug, comprising three herb fruits, including Terminalia chebula (Haritaki), bellirica (Bibhitaki), and Phyllanthus emblica (Amalaki). It enriched with vitamin C, polyphenols, flavonoids, sterols, saponins, etc., well-documented for its potent antioxidant, anticancer, chemoprotective, antimicrobial, anti-inflammatory effects. This research was conducted to evaluate the synergistic antioxidative cytotoxic potential of mixtures individual constituents at their...