A5100620346- Leptospirosis research and findings
- Child Nutrition and Water Access
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Cholesterol and Lipid Metabolism
- Milk Quality and Mastitis in Dairy Cows
- Phytochemicals and Antioxidant Activities
- Microbial infections and disease research
- Vascular Malformations Diagnosis and Treatment
- Marine Bivalve and Aquaculture Studies
- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Computational Drug Discovery Methods
- Arsenic contamination and mitigation
- Marine and fisheries research
- Intracranial Aneurysms: Treatment and Complications
- Probiotics and Fermented Foods
- Escherichia coli research studies
- Cancer therapeutics and mechanisms
- Anesthesia and Pain Management
- Natural Antidiabetic Agents Studies
- Fish Biology and Ecology Studies
- Pesticide Residue Analysis and Safety
- Global Maternal and Child Health
- Animal Nutrition and Physiology
Indo Soviet Friendship College of Pharmacy
2025
BRAC University
2025
Bangladesh Agricultural University
2014-2024
University of Chittagong
2021-2024
Biomedical Research Foundation
2022-2024
Dhaka Medical College and Hospital
1970-2024
National Institute of Cardiovascular Diseases
2024
Directorate General of Health Services
2024
Dinajpur Medical College
2022-2024
Gopalganj Science and Technology University
2023
We have recently reported that phytosteryl ferulates isolated from rice bran inhibit nuclear factor-kappaB (NF-kappaB) activity in macrophages. In the present study, we investigated effect of gamma-oryzanol (gamma-ORZ), a mixture ferulates, cycloartenyl ferulate (CAF), one components gamma-ORZ, and ferulic acid (FA), possible metabolite gamma-ORZ vivo, on model colitis mice.We induced with dextran sulphate sodium (DSS) mice monitored disease index (DAI), histopathology score, tissue...
Abstract Background Antioxidants play an important role to protect damage caused by oxidative stress (OS). Plants having phenolic contents are reported possess antioxidant properties. The present study was designed investigate the properties and (total phenols, flavonoids, flavonols proanthrocyanidins) of methanolic extracts from Morus alba (locally named as Tut commonly known white mulberry) stem barks (TSB), root bark (TRB), leaves (TL) fruits (TF) make a statistical correlation between...
Pancreatic cancer is a very deadly disease with 5-year survival rate, making it one of the leading causes cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) ubiquitously expressed protein in pancreatic cancer. FAK, tyrosine that overexpressed cells, crucial for development tumors into malignant phenotypes. FAK functions response to extracellular signals by triggering transmembrane receptor signaling, which enhances focal turnover, cell adhesion, migration, and gene expression....
Abstract Background The use of plants and their derived substances increases day by for the discovery therapeutic agents owing to versatile applications. Current research is directed towards finding naturally-occurring antioxidants having anticancer properties from plant origin since oxidants play a crucial role in developing various human diseases. present study was designed investigate antioxidant Sygygium fruticosum (Roxb.) (abbreviated as SF). Methods dried coarse powder seeds SF...
Abstract Background Safe water is essential for life but unsafe human consumption if it contaminated with pathogenic microorganisms. An acceptable quality of supply (adequate, safe and accessible) must be ensured to all beings a healthy life. Methods We collected analyzed total 12,650 drinking samples, the presence Escherichia coli faecal coliforms, from large habitation displaced Rohingya population comprising about 1.16 million people living within 4 km 2 . Results found that 28% (n = 893)...
E. coli is one of the major significant pathogens causing mastitis, most complex and costly diseases in dairy industry worldwide. Present study was undertaken to isolate, detect virulence factors, phylogroup, antimicrobial susceptibility resistance genes from cows with clinical mastitis. A total 68 milk samples comprising 53 mastitis 15 apparently healthy cattle were collected four different established farms Bangladesh. isolated identified by PCR targeting malB gene sequencing 16S rRNA...
Antibiotic therapy is essential in human and veterinary medicine, but resistance prolonged exposure to antibiotic residues pose significant risks health. This study investigated the long-term effects of amoxicillin residue on Swiss Albino male mice. Mice (n=20) were divided into control (no antibiotics) treated (amoxicillin at rate 10 ppm drinking water for one year; MRL 0.01 ppm) groups. Body weight, physical condition, immune status, blood parameters, ALT AST enzyme levels, histopathology...
The current study sought to determine the pharmacological characteristics of crude methanolic extract (MPF) Pandanus fascicularis Lam. root and its soluble ethyl acetate (EAPF) chloroform (CPF) fractions through in vivo vitro approaches. This herb has been used for generations Bangladesh heal a variety human diseases. Qualitative phytochemical tests confirmed presence alkaloid, glycoside, flavonoid, tannin, resin etc. CPF exhibited highest antioxidative potential DPPH (2, 2-Diphenyl -1-...
Antimicrobial resistance (AMR) in Salmonella poultry poses a serious human health threat as it has zoonotic importance. Poultry is often linked with outbreaks of Salmonella-associated foodborne illness. Since antimicrobials are heavily used Bangladesh, multidrug-resistant (MDR) quite frequently found there. MDR challenging to treat and causes severe economic loss the sector. By horizontal gene transfer and/or evolutionary mutations, primarily exert selection pressure that contributes...
Antimicrobial resistance has recently been considered an emerging catastrophe globally. The public health and environmental threats were aggravated by the injudicious use of antibiotics in animal farming, aquaculture, croup fields, etc. Consequently, failure antibiotic therapies is common because emergence multidrug-resistant (MDR) bacteria environment. Thus, reduction spillage environment could be important step for overcoming this situation. Bear mind, research was focused on green...
Spirochaetes are spiral or flat-wave-shaped Gram-negative bacteria that have periplasmic flagella between the peptidoglycan layer and outer membrane. Rotation of transforms cell body shape periodically, allowing to swim in aqueous environments. Because virulence motility-deficient mutants pathogenic species is drastically attenuated, motility thought be an essential factor spirochaetes. However, it remains unknown how practically contributes infection process. We show here configuration...
To assess the relative risk of mortality in infants born preterm and small for gestational age (SGA) during first second months life rural Bangladesh.
Some of the pharmacological properties spirulina (Spirulina platensis) may be linked to its antioxidant potential, which mitigates oxidative stresses. In this study we examined whether mitigated arsenic-induced toxicity in Black Bengal goat (Capra hircus). Nonpregnant female goats approximately 12 months old were used noninduced, nontreated control (T_1); arsenic-induced, (T_2); and spirulina-treated (T_3) groups. Groups T_2 T_3 given sodium arsenite orally (5 mg/kg) daily for 15 weeks. For...
Tenascin-C (TnC) is a multi-domain extracellular matrix glycoprotein that expressed at high level during embryogenesis but almost absent normal postnatal life. This complex molecule reported to associate with both pro-inflammatory and anti-inflammatory signalling cascades. In this study, we examined how TnC modulated intestinal inflammation.TnC pathophysiology was evaluated in cultures of rat subepithelial myofibroblasts (ISEMF) epithelial cells. Wild-type TnC(-/-) mice were treated dextran...