- Advanced biosensing and bioanalysis techniques
- Molecular Junctions and Nanostructures
- Electrochemical sensors and biosensors
- Neuroscience and Neural Engineering
- Electrochemical Analysis and Applications
- Biosensors and Analytical Detection
- Conducting polymers and applications
- Advanced Biosensing Techniques and Applications
- Photoreceptor and optogenetics research
- Analytical Chemistry and Sensors
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Force Microscopy Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Photosynthetic Processes and Mechanisms
- Nanofabrication and Lithography Techniques
- Microfluidic and Bio-sensing Technologies
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Lipid Membrane Structure and Behavior
- Nanowire Synthesis and Applications
- Porphyrin and Phthalocyanine Chemistry
- Advanced Fluorescence Microscopy Techniques
- Advanced Sensor and Energy Harvesting Materials
- Nanoparticle-Based Drug Delivery
Sogang University
2016-2025
The University of Texas Southwestern Medical Center
2023-2025
Southwestern Medical Center
2023-2025
Kongju National University
2025
Highland Community College - Illinois
2025
Neurological Surgery
2022-2025
Ewha Womans University
2025
University of Wisconsin–Madison
2024
National Institute of Environmental Research
2023
Yonsei University
2002-2022
Swim into the light A bio-inspired swimming robot that mimics a ray fish can be guided by light. Park et al. built 1/10th-scale version of with microfabricated gold skeleton and rubber body powered rat heart muscle cells. The cardiomyocytes were genetically engineered to respond cues, so undulatory movements propelling through water would follow source. Science , this issue p. 158
Cell-free DNA (cfDNA) has attracted significant attention due to its high potential diagnose diseases, such as cancer. Still, detection by amplification method limitations because of false-positive signals and difficulty in designing target-specific primers. CRISPR-Cas-based fluorescent biosensors have been developed but also need the step for detection. In this study, first time CRISPR-Cas12a based nucleic acid amplification-free biosensor was detect cfDNA a metal-enhanced fluorescence...
Nucleic acid biomarkers have been widely used to detect various viral-associated diseases, including the recent pandemic COVID-19. The CRISPR-Cas-based trans-activating phenomenon has shown excellent potential for developing sensitive and selective detection of nucleic acids. However, amplification steps are typically required when monitoring target is needed. To overcome aforementioned challenges, we developed a CRISPR-Cas12a-based amplification-free biosensor by surface-enhanced Raman...
Carbon nanomaterials have attracted significant attention in the biomedical field, including for biosensing, drug delivery, and tissue engineering applications. Based on their inherent properties such as unique structure high conductivity, carbon can overcome current limitations research poor stability of biomolecules, low sensitivity selectivity biosensors, difficulty precise delivery. In addition, recently, several novel been integrated with to develop carbon-based nanocomposites...
Optimal detection of a pathogen present in biological samples depends on the ability to extract DNA molecules rapidly and efficiently. In this paper, we report novel method for efficient extraction subsequent real-time single microchip by combining laser irradiation magnetic beads. By using 808 nm carboxyl-terminated beads, demonstrate that pulse 40 seconds lysed pathogens including E. coli Gram-positive bacterial cells as well hepatitis B virus mixed with human serum. We further was...
Graphene is a single-atom thick, two-dimensional sheet of carbon that characterized by exceptional chemical, electrical, material, optical, and physical properties. As result, graphene related materials, such as oxide reduced oxide, have been brought to the forefront in field sensing. Recently, number reports demonstrated graphene–nanoparticle hybrid structures can act synergistically offer unique physicochemical properties are desirable advantageous for sensing applications. These...
Municipal wastewater treatment plants (WWTPs) in Korea collect and treat not only domestic wastewater, but also discharge from industrial complexes. However, some discharges contain a large amount of non-biodegradable organic matter, which cannot be treated properly conventional biological WWTP. This study aimed to investigate the characteristics biodegradability matter contained examine fate In contrast most previous studies targeting specific group compounds or traditional water quality...
Control of stem cell fate by modulating biophysical cues (e.g., micropatterns, nanopatterns, elasticity and porosity the substrates) has emerged as an attractive approach in cell-based research. Here, we report a method for fabricating combinatorial patterns graphene oxide (GO) to effectively control differentiation human adipose-derived mesenchymal cells (hADMSCs). In particular, GO line were highly effective morphology hADMSCs, resulting enhanced hADMSCs into osteoblasts. Moreover,...
Abstract Organic matter (OM) and suspended sediment are abundant, interact with each other, in rivers lakes. OM is usually adsorbed by causes either particle stabilization or flocculation. In this study, the composition flocculation potential of river water were regularly measured throughout year 2016. The samples was a liquid chromatography‐organic carbon detection system fluorescence excitation‐emission matrix spectroscopy, standard jar test experiment. Results from analyses tests,...
Although fluorescence-based analytical methods have been used in intracellular analyses, their sensitivity is low for the precise analysis of proteolytic enzymes to observe cell apoptosis related cancer and neurodegenerative diseases. In this study, a metal-enhanced-fluorescence (MEF)-based highly sensitive biosensor detection proposed first time by using bifunctional Au nanoparticle (AuNP), which connected fluorophore both single-stranded DNA (ssDNA) peptide. Once caspase-3, enzyme, cuts...
Nanoparticle-based nucleic acid conjugates (NP-NACs) hold great promise for theragnostic (diagnostic and therapeutic) applications. However, several limitations have hindered the realization of their full potential in clinical treatment cancer other diseases. In diagnosis, NP-NACs, combined with conventional optical sensing systems, been applied detection