A5004445429- Hair Growth and Disorders
- Cancer Genomics and Diagnostics
- Extracellular vesicles in disease
- Renal and related cancers
- Pluripotent Stem Cells Research
- Nanoplatforms for cancer theranostics
- Dermatologic Treatments and Research
- melanin and skin pigmentation
- Skin and Cellular Biology Research
- Cell Adhesion Molecules Research
- Advanced Nanomaterials in Catalysis
- Cell Image Analysis Techniques
- Tissue Engineering and Regenerative Medicine
- Plant Molecular Biology Research
- Immune cells in cancer
- 3D Printing in Biomedical Research
- Advanced Fluorescence Microscopy Techniques
- CRISPR and Genetic Engineering
- Genomic variations and chromosomal abnormalities
- Wnt/β-catenin signaling in development and cancer
- Prenatal Screening and Diagnostics
- Mesenchymal stem cell research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Evolution and Genetic Dynamics
Kyungpook National University
2017-2024
Kyungpook National University Hospital
2017-2022
Aims: Extracellular vesicles (EVs) are membrane-derived that mediate intercellular communications. Neutrophils produce different subtypes of EVs during inflammatory responses. Neutrophil-derived trails (NDTRs) generated by neutrophils migrating toward foci, whereas neutrophil-derived microvesicles (NDMVs) thought to be have arrived at the foci. However, physical and functional characteristics incompletely understood. In this study, we aimed investigate differences between NDTRs NDMVs....
The control principles behind robust cyclic regeneration of hair follicles (HFs) remain unclear. Using multi-scale modeling, we show that coupling inhibitors and activators with physical growth HFs is sufficient to drive periodicity excitability regeneration. Model simulations experimental data reveal mouse skin behaves as a heterogeneous regenerative field, composed anatomical domains where have distinct cycling dynamics. Interactions between fast-cycling chin ventral slow-cycling dorsal...
Maintenance of trichogenecity dermal papilla cells (DPCs) have been a problem during cell therapy for androgenic alopecia, as they lose their regenerative potential in vitro culture. Various spheroid culture techniques are used to increase and maintain these cells. However, there some critical drawbacks methods. Applying hydrocell plate sphere formation or hanging drop methods by hand would be difficult control the size density inside it. It commercialize mass production clinical therapy. In...
SUMMARY Extracellular vesicles (EVs) are membrane-derived that mediate intercellular communications. Neutrophils produce different subtypes of EVs during inflammatory responses. Neutrophil-derived trails (NDTRs) generated by neutrophils migrating toward foci, whereas neutrophil-derived microvesicles (NDMVs) thought to be have arrived at the foci. However, physical and functional characteristics incompletely understood. In this study, we investigated similarities differences between EV...
Summary The trillions of cells that constitute the human body are developed from a fertilized egg through embryogenesis. However, cellular dynamics and developmental outcomes embryonic in humans remain to be largely unknown due technical ethical challenges. Here, we explored whole-genomes 334 single-cell expanded clones targeted deep-sequences 379 bulk tissues obtained various anatomical locations seven individuals. Using discovered 1,688,652 somatic mutations as an intrinsic barcode,...
Extracellular vesicles (EVs) are membrane-derived that mediate intercellular communications. Neutrophils produce different subtypes of EVs during inflammatory responses. Neutrophil-derived trails (NDTRs) generated by neutrophils migrating toward foci, whereas neutrophil-derived microvesicles (NDMVs) thought to be have arrived at the foci. However, physical and functional characteristics incompletely understood. In this study, we investigated similarities differences between EV subtypes....
Optical imaging of the vascular system is necessary for structural, functional, developmental, and pathological biology.Recent developments in optical tissue-clearing methods have significantly advanced largescale tissue researches by integrating a three-dimensional (3D) visualization topographical vasculature, so we aimed to enhance structure murine pancreas which are highly vascularized structure.In this study, adult C57/BL6 pancreatic was cleared after lectin staining, resulting...