A5029548745- Respiratory viral infections research
- Respiratory Support and Mechanisms
- Global Maternal and Child Health
- Pneumonia and Respiratory Infections
- Child Nutrition and Water Access
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Emergency and Acute Care Studies
- Phonocardiography and Auscultation Techniques
- COVID-19 diagnosis using AI
- Ultrasound in Clinical Applications
- COVID-19 epidemiological studies
- Maternal and Neonatal Healthcare
- Birth, Development, and Health
- Bacterial Infections and Vaccines
- Air Quality and Health Impacts
- Global Health and Epidemiology
- Literature Analysis and Criticism
- Noise Effects and Management
- COVID-19 Clinical Research Studies
- Voice and Speech Disorders
- Energy and Environment Impacts
- Early Childhood Education and Development
- Infant Nutrition and Health
Biomedical Research Foundation
2020-2024
Johns Hopkins University
2016-2024
Bloomberg (United States)
2020
Bangabandhu Sheikh Mujib Medical University
2020
International Centre for Diarrhoeal Disease Research
2016
Creative Commons
2016
Gates Foundation
2016
Child Health Research Foundation
2016
The safety and efficacy of antenatal glucocorticoids in women low-resource countries who are at risk for preterm birth uncertain.
Children's early development is affected by caregiving experiences, with lifelong health and well-being implications. Governments civil societies need population-based measures to monitor children's ensure that children receive the care needed thrive. To this end, WHO developed Global Scales for Early Development (GSED) measure up 3 years of age. The GSED includes three population programmatic level measurement: (1) short form (SF) (caregiver report), (2) long (LF) (direct administration)...
We aimed to understand the mortality risks of vulnerable newborns (defined as preterm and/or born weighing smaller or larger compared a standard population), in low- and middle-income countries (LMICs).Descriptive multi-country, secondary analysis individual-level study data babies since 2000.Sixteen subnational, population-based studies from nine LMICs sub-Saharan Africa, Southern Eastern Asia, Latin America.Live birth neonates.We categorically defined five newborn types based on size...
ABSTRACT Background Infant pulmonary function testing (iPFT) in low‐ and middle‐income countries is limited. We evaluated the early feasibility of iPFT rural Bangladesh. Methods Experts established an laboratory at Zakiganj Upazila Health Complex Sylhet, Bangladesh trained staff. Infants ≤ 6 months old participating a cohort study between 2021 2022 were eligible for respiratory oscillometry (Osc), tidal breath flow‐volume loops (TBFVL), sulphur hexaflouride multiple washout (MBW) during...
Abstract Objective To describe the mortality risks by fine strata of gestational age and birthweight among 230 679 live births in nine low‐ middle‐income countries (LMICs) from 2000 to 2017. Design Descriptive multi‐country secondary data analysis. Setting Nine LMICs sub‐Saharan Africa, Southern Eastern Asia, Latin America. Population Liveborn infants 15 population‐based cohorts. Methods Subnational, studies with high‐quality birth outcome were invited join Vulnerable Newborn Measurement...
To assess the relative risk of mortality in infants born preterm and small for gestational age (SGA) during first second months life rural Bangladesh.
In low-income settings, community health workers (CHWs) are frequently the first point of contact for newborns. Mobile technology may aid in classifying illness and providing referral management guidance newborn care. This study evaluates potential mobile to improve diagnosis case newborns Bangladesh. A application based on Bangladesh's Comprehensive Newborn Care Package national guidelines (mCNCP) was developed CHWs identifying managing small sick infants. After a 2-day training, assessed...
Hypoxemia measured by pulse oximetry predicts child pneumonia mortality in low-resource settings (LRS). Existing pediatric oximeter probes are prohibitively expensive and/or difficult to use, limiting LRS implementation. Using a human-centered design, we developed low-cost, reusable probe for health-care workers (HCWs). Here, report usability testing. Fifty-one HCWs from Malawi, Bangladesh, and the United Kingdom participated, seven experts provided reference measurements. Health-care...
Despite the high rate of deaths in young infants (0-59 days) attributable to infections resource-poor countries, data on bacterial and viral etiologies community-acquired this age group are limited. These needed develop appropriate preventive strategies suitable antibiotic treatment regimens for reducing number infant from infections. The Aetiology Neonatal Infection South Asia (ANISA) study is designed generate these critical being implemented Bangladesh, India Pakistan. Sylhet site...
Background WHO defines hypoxaemia, a low peripheral arterial oxyhaemoglobin saturation (SpO 2 ), as <90%. Although hypoxaemia is an important risk factor for mortality of children with respiratory infections, the optimal SpO threshold defining uncertain in low-income and middle-income countries (LMICs). We derived from well Bangladesh residing at altitude. Methods prospectively enrolled well, aged 3–35 months participating pneumococcal vaccine evaluation Sylhet district, between June...
Background Bangladesh introduced the 10-valent pneumococcal conjugate vaccine (PCV-10) in 2015. We measured population-based incidence of invasive disease (IPD) prior to introduction PCV-10 provide a benchmark against which impact can be assessed. Methods conducted population, facility and laboratory-based surveillance children 0–59 months age three rural sub-districts Sylhet district from January 2014 June All received two-monthly home visits with one week recall for morbidity care seeking....
Background Pulse oximeters are not routinely available in outpatient clinics low- and middle-income countries. We derived clinical scores to identify hypoxemic child pneumonia. Methods This was a retrospective pooled analysis of two datasets 3–35 month olds with World Health Organization (WHO)-defined pneumonia Bangladesh Malawi. constructed, internally validated, compared fit &amp; discrimination four models predicting SpO 2 &lt; 93% &lt;90%: (1) Integrated Management Childhood...
Bangladesh reported its first COVID-19 case on March 8, 2020. Despite lockdowns and promoting behavioural interventions, as of December 31, 2021, 1.5 million confirmed cases 27 904 COVID-19-related deaths. To understand the course pandemic identify risk factors for SARs-Cov-2 infection, we conducted a cohort study from November 2020 to 2021 in rural Bangladesh.
While chest auscultations provide an accessible and low-cost tool for pediatric pneumonia diagnosis, its subjectivity low reliability continues to hinder inclusion in global guidelines; eventhough more robust tools like radiography also suffer from cost accessibility issues. Advances computer-aided analytics is offering interpreting digital auscultation signals though little has been done explore variations of lung sounds across different positions the correspondence between specific...
ABSTRACT Background Acute lower respiratory tract infections (ALRIs) remain the leading infectious cause of death among children < 5 years, with viruses contributing to a large proportion cases. Little is known about epidemiology and etiology viral ALRI in rural Bangladesh. Methods We enrolled 3‐ 23‐month‐old ALRIs attending subdistrict hospital outpatient clinic Sylhet district Trained study physicians ascertained cases obtained nasopharyngeal swabs detect 19 by multiplex PCR using...
<title>Abstract</title> Background Low birth weight (LBW, birthweight < 2500 gm) is associated with a significantly increased risk of morbidity and mortality during infancy an important contributor to childhood developmental delays. Methods To estimate the incidence LBW identify its factors, we analyzed data from population-based cohort study, Aetiology Neonatal Infections in South Asia, conducted two sub-districts Sylhet district Bangladesh. The study followed 24,271 pregnant women 2011...
Abstract Background: Considering the high frequency of respiratory infections among children in low- and middle-income countries (LMICs), World Health Organization (WHO) developed a pragmatic guideline for managing pneumonia low-resource settings. The guideline’s low specificity leads to many false-positive cases receiving antibiotic treatment. Integrating diagnostic technology incorporate lung sounds into WHO guidelines could improve childhood diagnosis management. This qualitative study...
ABSTRACT Background Pulse oximeters are not routinely available in outpatient clinics low- and middle-income countries. We derived clinical scores to identify hypoxemic child pneumonia. Methods This was a retrospective pooled analysis of two datasets 3-35 month olds with World Health Organization (WHO)-defined pneumonia Bangladesh Malawi. constructed, internally validated, compared fit & discrimination four models predicting SpO2<93% <90%: (1) Integrated Management Childhood...