A5064001197- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Shoulder Injury and Treatment
- Colorectal Cancer Treatments and Studies
- Advanced Chemical Sensor Technologies
- Orthopaedic implants and arthroplasty
- Anorectal Disease Treatments and Outcomes
- Chronic Disease Management Strategies
- Stoma care and complications
- Genetic factors in colorectal cancer
- Palliative Care and End-of-Life Issues
- Olfactory and Sensory Function Studies
- COVID-19 Clinical Research Studies
- Total Knee Arthroplasty Outcomes
- Biochemical Analysis and Sensing Techniques
- Orthopedic Infections and Treatments
- Ethics in Clinical Research
- Thermal Regulation in Medicine
- Advanced biosensing and bioanalysis techniques
- Allergic Rhinitis and Sensitization
- Genomics and Rare Diseases
- Pain Management and Opioid Use
- Analytical Chemistry and Chromatography
Isala
2019-2025
Spaarne Gasthuis
2014
Amsterdam UMC Location Vrije Universiteit Amsterdam
2013
Spaarne Ziekenhuis
2012
Radboud University Nijmegen
1990
Background and study aims: Cecal intubation is not achieved in 2 – 23 % of colonoscopies. The efforts made by physicians to visualize the remaining colon number missed significant lesions are unknown. This evaluates 1) reasons for incomplete colonoscopy, 2) rates complete colonic evaluation after 3) (pre-) malignant colonoscopy.
<h3>Background</h3> Rectal measurement is considered a gold standard in many healthcare systems for body temperature children. Although this method has several disadvantages, an ideal alternative thermometer not yet been introduced. However tympanic and infrared skin thermometers are potential alternatives. <h3>Methods</h3> A prospective cohort study was performed including 100 children between 0 18 years of age admitted to the general paediatric ward Spaarne Hospital The Netherlands January...
The global push for the use of hydroxychloroquine (HCQ) and chloroquine (CQ) against COVID-19 has resulted in an ongoing discussion about effectivity toxicity these drugs. Recent studies report no effect (H)CQ on 28-day mortality. We investigated HCQ CQ hospitalized patients non-ICU COVID-ward.A nationwide, observational cohort study was performed Netherlands. Hospitals were given opportunity to decide independently three different treatment strategies: HCQ, CQ, or treatment. compared...
PURPOSE The use of real-world data (RWD) in oncology is becoming increasingly important for clinical decision making and tailoring treatment. Despite the significant success targeted therapy immunotherapy advanced melanoma, substantial variability responses to these treatments emphasizes need personalized approaches therapy. MATERIALS AND METHODS In this pilot study, 239 patients with melanoma were included predict response both therapies immunotherapies. We used machine learning (ML)...
Abstract Background The role of radiological staging and surveillance imaging is under debate for T1 colorectal cancer (CRC) as the risk distant metastases low may lead to detection incidental findings. Objective aim this study was evaluate yield CRC. Methods In retrospective multicenter cohort study, all patients 10 Dutch hospitals with histologically proven CRC who underwent in period 2000–2014 were included. Clinical characteristics, pathological, endoscopic, surgical reports at baseline...
Pneumatic compression and cryotherapy have been successfully being employed in the management of acute tissue damage. The Game Ready System (GRS) combines cyclic cryotherapy. No randomised controlled trial has performed on effects combined total hip arthroplasty (THA). We observed postoperative pain, morphine usage, blood loss, wound discharge, patient medical staff satisfaction, together with feasibility a cryocompression machine, hospital admission time, infection rate, deep vein...
Adequate bowel preparation is an important step for effective colonoscopy. Polyethylene glycol solution (Kleanprep) and sodium picosulphate with a magnesium citrate (Picoprep) are cleansing agents registered available this purpose. So far, the results of studies comparing effectiveness between two inconclusive. This may be because differences in administration regimes subjective measurement cleansing.In single-blinded randomized-controlled trial, Kleanprep Picoprep was examined using...
As current follow-up modalities for colorectal carcinoma (CRC) have restricted sensitivity, novel diagnostic tools are needed. The presence of CRC changes the endogenous metabolism, resulting in release a specific volatile organic compounds (VOC) pattern that can be detected with an electronic nose or AeonoseTM. To evaluate use CRC, we studied effect curative surgery on VOC recognition using A prospective cohort study was performed, which 47 patients diagnosed were included, all whom...
We evaluated a prosthesis-retaining treatment protocol for prosthetic joint infection in patients presenting at mean of 116 days (range 10-1216 days) after primary arthroplasty. Our regime involved irrigation and debridement followed by implantation biodegradable gentamicin loaded sponges which do not require removal implantation. Of 34 with deep total hip arthroplasty, Twenty-five were treated successfully, follow-up 35 months. There no permanent complications. This success rate is...
Introduction: A watch-and-wait strategy for patients with rectal cancer who achieve a clinical complete response after neoadjuvant (chemo) radiotherapy is valuable alternative to resection. In this pilot study, we explored the use of an electronic nose predict therapy by analyzing breath-derived volatile organic compounds. Materials and Methods: study was performed between 2020 2022 on diagnosed intermediate- or high-risk were scheduled therapy. Breath samples collected before radiotherapy....
Pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) is found in 15-20% of patients with locally advanced rectal cancer. A watch-and-wait (W&W) strategy has been introduced as an alternative to avoid surgery for selected a clinical at multidisciplinary evaluation. The primary aim this study was evaluate the efficacy evaluation by comparing proportion pCR since introduction structural period before evaluation.This retrospective cohort enrolled cancer who underwent...
By making use of preparative field inversion gel electrophoresis, we have constructed a lambdaZAP library that is highly enriched for sequences from the chorolderemia locus. In vivo excision pBluescript SK(–) constructs obviates subcloning DNA inserts and allows rapid processIng several hundred recombinants. From 625 kb Sf/1 fragment isolated 7 clones were physically mapped using microdeletlons associated with disease. One these located within, or Just telomeric to, gene detects two...
Health claims data may be an efficient and easily accessible source to study chronic kidney disease (CKD) prevalence in a nationwide population. Our aim was Dutch for their ability identify CKD patients different subgroups. From laboratory database, we selected 24 895 adults with at least one creatinine measurement 2014 ordered outpatient clinic. Of these, 15 805 had ≥2 measurements 3 months apart could assessed the chronicity criterion. We estimated validity of claim-based diagnosis...
Does assisted hatching increase the cumulative live birth rate in subfertile couples with repeated implantation failure?