A5011289093- Thermoregulation and physiological responses
- Systemic Sclerosis and Related Diseases
- Dermatologic Treatments and Research
- Health Systems, Economic Evaluations, Quality of Life
- Infrared Thermography in Medicine
- Pharmacovigilance and Adverse Drug Reactions
- Statistical Methods in Clinical Trials
- Mast cells and histamine
- Heart Rate Variability and Autonomic Control
- Pulmonary Hypertension Research and Treatments
- Pharmaceutical Practices and Patient Outcomes
- Diagnosis and Treatment of Venous Diseases
- Diabetic Foot Ulcer Assessment and Management
- COVID-19 Clinical Research Studies
- Wound Healing and Treatments
- SARS-CoV-2 and COVID-19 Research
- Diabetes Treatment and Management
- Meta-analysis and systematic reviews
- Drug-Induced Adverse Reactions
- Pharmaceutical Economics and Policy
- Renal Transplantation Outcomes and Treatments
- Climate Change and Health Impacts
- Biosimilars and Bioanalytical Methods
- Sympathectomy and Hyperhidrosis Treatments
- Biochemical Analysis and Sensing Techniques
Inserm
2016-2025
Université Grenoble Alpes
2016-2025
Centre Hospitalier Universitaire de Grenoble
2016-2025
Centre d'Investigation Clinique - Innovation Technologique
2009-2023
Laboratoire de Biophotonique et Pharmacologie
2021
University of Georgia
2021
Clinical Investigation Center Plurithematic Tours
2011-2020
Beth Israel Deaconess Medical Center
2016-2020
Physiopathologie et Epidémiologie des Maladies Respiratoires
2019-2020
Grenoble Institute of Neurosciences
2017
This disproportionality analysis uses the World Health Organization pharmacovigilance database to explore potential safety signal of facial paralysis after COVID-19 vaccination.
Objectives: We aimed to assess the impact of an automated dispensing system on incidence medication errors related picking, preparation, and administration drugs in a medical intensive care unit. also evaluated clinical significance such user satisfaction. Design: Preintervention postintervention study involving control intervention Setting: Two units same department 2,000-bed university hospital. Patients: Adult patients. Interventions: After 2-month observation period, we implemented one...
Nonhealing diabetic foot ulcers (DFUs) are characterized by low-grade chronic inflammation, both locally and systemically. We prospectively followed a group of patients who either healed or developed nonhealing DFUs. Serum forearm skin analysis, at the protein expression transcriptomic level, indicated that increased factors such as interferon-γ (IFN-γ), vascular endothelial growth factor, soluble cell adhesion molecule-1 were associated with DFU healing. Furthermore, single-cell RNA...
Inhibitors of the sodium‐glucose co‐transporter‐2 (SGLT‐2) are a novel class glucose‐lowering agents that show promising results. However, use canagliflozin has been associated with an increased risk lower‐limb amputation. Whether this concerns other SGLT‐2 inhibitors is unclear, and our objective was to address issue. We performed disproportionality analysis using WHO global database individual case safety reports (VigiBase). Among 8 293 886 available between January 2013 December 2017, we...
Previous meta-epidemiological surveys have found considerable misinterpretation of results disproportionality analyses. We aim to explore the relationship between strength causal statements used in title and abstract conclusions pharmacovigilance analyses language citing studies. On March 30, 2022, we selected 30 studies with highest Altmetric Attention Scores. For each article, extracted all using Dimension database (n = 1434). In parallel, two authors assessed source articles paragraph...
Abstract Context: Cardiovascular risk factors are well-known predictors of the development diabetic peripheral neuropathy (DPN), which has traditionally been considered as a manifestation diabetes-associated microangiopathy. Because endothelial dysfunction is strongly associated with all cardiovascular factors, we hypothesized that it may be link between and DPN. Objective: The primary objective this study was to test whether predictor Design Setting: This cross-sectional analysis cohort...
Nonadherence to immunosuppressive (IS) therapy is associated with poor outcomes. Identifying factors predicting adherence therefore essential. The primary objective of this study was test whether parameters a model adapted from the theory planned behavior, and more specifically attitudes that are influenced by beliefs satisfaction medication, could predict in solid organ transplant patients.Adherence assessed self-reported medication scale IS blood trough concentrations over 6 months, four...
Objective. Concerns have been raised about nonadherence behavior among patients with chronic inflammatory rheumatic diseases (CIRD) receiving biologics. This may be caused by various factors. The main objective was to explain why discontinue their biologics of own accord. Methods. A quantitative and descriptive study performed using a self-report questionnaire that sent through the Internet members different patient associations. Sociodemographic data, medical therapeutic history, management...
The pathophysiology of pulmonary arterial hypertension (PAH) induced by protein kinase inhibitors (PKIs) remains unclear. To gain knowledge into this rare and severe pathology we performed a study combining pharmacovigilance approach the pharmacodynamic properties PKIs.A disproportionality analysis on World Health Organization database VigiBase using reporting odds ratio (ROR) 95% confidence interval was first performed. Then, identified most relevant cellular targets interest through...