- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Blood donation and transfusion practices
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Transplantation: Methods and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Systems and Practices
- Acute Myocardial Infarction Research
- Peripheral Artery Disease Management
- Stuttering Research and Treatment
- Atrial Fibrillation Management and Outcomes
- Clinical Reasoning and Diagnostic Skills
- Cardiovascular Health and Risk Factors
- Pharmaceutical studies and practices
- Cardiac pacing and defibrillation studies
- Hip and Femur Fractures
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Neurological Disorders and Treatments
Duke University
2022-2025
Clinical Research Institute
2022-2024
The University of Texas Southwestern Medical Center
2024
University of Virginia
2024
Duke University Hospital
2022
Duke Medical Center
2022
US nationwide estimates of the proportion patients newly diagnosed with heart failure reduced ejection fraction (HFrEF) eligible for quadruple medical therapy, and associated benefits rapid implementation, are not well characterized. This study sought to characterize degree which HFrEF projected in-hospital initiation. Among hospitalized in Get With The Guidelines – Heart Failure registry from 2016-2023, eligibility criteria based on regulatory labeling, guidelines, expert consensus...
Abstract Aims Sex differences in long‐term outcomes following hospitalization for heart failure (HF) across ejection fraction (EF) subtypes are not well described. In this study, we evaluated the risk of mortality and rehospitalization among males females spectrum EF over 5 years follow‐up an index HF event. Methods results Patients hospitalized with between 1 January 2006 31 December 2014 from American Heart Association's Get With The Guidelines‐Heart Failure registry available 5‐year using...
Background: The prevalence of renal disease is increasing in the U.S. Renal dysfunction increases risk atrial fibrillation, ischemic stroke and systemic bleeding. Lack randomized trial data this population has led to conflicting recommendations on management. Our objective was review a decade practice utilization antithrombotics including oral anticoagulants (OACs) for secondary prevention patients with severe dysfunction. Methods: We analyzed all fibrillation impaired function (creatinine...
Introduction: Anticoagulation therapy plays a pivotal role in stroke prevention for people with atrial fibrillation. Despite its efficacy, some patients still have an ischemic while on therapy. Since it remains unclear how best to modify risk these cases and guidance clinical decision-making is limited, understanding real-world patterns crucial improving outcomes. Methods: Using data from the Get With The Guidelines-Stroke Registry between 2016 2023, we assessed strategies clinicians use...
Fewer than 20% of eligible patients with heart failure reduced ejection fraction receive all 4 pillars guideline-directed medical therapy. Understanding disparities by race, ethnicity, sex, and adverse social determinants health is necessary to equitably optimize quadruple
Black adults with heart failure (HF) disproportionately experience higher population-level mortality than White HF. Whether quality of care for HF differs at hospitals high proportions patients compared other is unknown.
ABSTRACT Background Guidelines recommend DIDO (Door-In-Door-Out) time < 120 minutes at the transferring emergency department (ED); however, it is unknown whether inter-hospital transfer times are related to clinical outcomes. Methods Retrospective, observational cohort study using US registry data from GWTG-Stroke participating hospitals. Patients age ≥18 years with intracerebral hemorrhage (ICH) or subarachnoid (SAH) January 1, 2019 July 31, 2022 who were transferred ED a...
A reliable method of predicting large vessel occlusion (LVO) stroke in data sets without neuroimaging could be retrospectively applied to expand research efforts.
Introduction: Less than 20% of eligible patients with heart failure reduced ejection fraction (HFrEF) receive all four pillars guideline-directed medical therapy (GDMT). Understanding disparities in sex, race, ethnicity, and adverse social determinants health (SDoH) is necessary to equitably optimize quadruple therapy. Methods: Utilizing the American Heart Association Get With The Guidelines® Failure registry, we conducted a retrospective cross-sectional study examine associations between...
Abstract Background Sex differences in 5-year outcomes across heart failure (HF) ejection fraction (EF) subtypes are not well known. Purpose To assess the interaction between sex and EF for risk of long-term adverse after hospitalization with HF. Methods Patients from American Heart Association’s Get With The Guidelines – Failure registry enrolled 1/1/2006 12/31/2014 age ≥ 65 years available follow-up data, ascertained through linkage Medicare fee-for-service Part A administrative claims,...
Background: Cardiovascular diseases, particularly heart failure (HF), are common reasons for interhospital transfer (IHT) in the United States. IHT targets patients requiring a higher level of care, and has been associated with increased cost, length stay (LOS), mortality. We aim to describe characteristics outcomes undergoing IHT, as well variation use across hospitals. Methods: Patients hospitalized HF who were admitted from another hospital compared those not within Get With The...
Heuristic biases are increasingly recognized, and potentially modifiable, contributors to patient care outcomes. Left digit bias is a cognitive where continuous variables categorized by their left-most digit. The impact of this heuristic applied age on quality in heart failure has not been explored.
Introduction: Black individuals have higher hospitalization and mortality rates from heart failure (HF). adults receive care at a limited set of US hospitals (minority-serving [MSH]) understanding quality these sites could inform efforts to improve health equity. Using the Get With The Guidelines (GWTG) - HF Registry, we compared clinical outcomes MSH vs. non-MSH. Methods: We identified ≥18 years hospitalized for GWTG-HF sites. were defined as top quintile proportion hospitalizations adults....