Solid–liquid two-phase flow with dense coarse particles in the pipeline exists widely energy and resources engineering, especially prospective hydraulic lifting scenario of deep-sea mining. In this paper, particles' transportation behavior a vertical pipe is investigated based on an optimized Eulerian–Lagrangian method proposed our previous work. The particle characterized as multi-processes multi-physical effects not fully captured due to limitations experimental apparatus, measurement...

The solid–liquid two-phase flow with coarse particles is ubiquitous in natural phenomena and engineering practice, which characterized by particles, high particle concentration, large size distribution. In this work, the numerical models describing flows are reviewed, given that Eulerian–Lagrangian method applicable work. Then, some modified proposed for situation where conventional not to deal particles. continuous phase equations of liquid solved based on finite volume method. pressure...

The solid–fluid two-phase flow with coarse particles is an important research object in the transportation field, such as deep-sea mining. This paper adopts resolved computational fluid dynamics-discrete element method to investigate motion and mechanical characteristics of during hydraulic collection. First, rising process by combining particle trajectory qualitative force analysis analyzed spiral phenomenon found through numerical results, centripetal reason for particle. Second,...

Ceramic microcomponents have a wide range of applications in microfluidic, sensors, etc. Stereolithography 3D printing technology provided shortcut for the preparation this small-size and complex component. With development device miniaturization, existing stereolithography forms cannot meet demand. To prepare smaller components, it is necessary to decrease slice thickness (Cs). But during printing, ceramic usually easy over-cure, leading key issue microcomponents: mismatching between curing...

To reduce the computational cost of multi-objective optimization process and improve accuracy fatigue life prediction for lower control arm (LCA) a vehicle under multiaxial random vibration, this paper focuses on LCA MacPherson suspension in specific model proposes lightweight design method based vibration fatigue. This combines Latin hypercube sampling (LHS) technique, Kriging surrogate modeling, second-generation non-dominated sorting genetic algorithm (NSGA-II). First, static dynamic...

ABSTRACT Sandy hydrate reservoirs are considered an ideal target for the extraction of marine natural gas hydrates (NGH). However, engineering geological risks, including reservoir sand production and seabed subsidence during process, present a significant challenge. In 2019, China discovered high‐concentration sandy NGH with favorable commercial development potential in Qiongdongnan Basin South Sea, establishing region as key focus future exploration efforts. A thorough comprehension...

Macrophage-1 Ag (Mac-1) and lymphocyte function-associated Ag-1 (LFA-1), two β2 integrins expressed on neutrophils (PMNs), mediate PMN recruitment cascade by binding to intercellular adhesive molecule 1. Distinct functions of LFA-1-initiating slow rolling firm adhesion but Mac-1-mediating cell crawling are assumed be governed the differences in their affinities kinetic rates. In this study, we applied an frequency approach compare kinetics quiescent activated states using three molecular...

Mechanics and surface microtopology of the molecular carrier influence cell adhesion, but mechanisms underlying these effects are not well understood. We used a micropipette adhesion frequency assay to quantify how stiffness affected two-dimensional kinetics interacting molecules on two apposing surfaces. Interactions P-selectin with glycoprotein ligand-1 (PSGL-1) were demonstrate such by presenting three systems: human red blood cells (RBCs), promyelocytic leukemia HL-60 cells, polystyrene...

Abstract A combination method of the Newton iteration and two‐level finite element algorithm is applied for solving numerically steady Navier‐Stokes equations under strong uniqueness condition. This motivated by applying m iterations problem on a coarse grid computing Stokes fine grid. Then, uniform stability convergence with respect to ν iterative solution are analyzed large small H h << . Finally, some numerical tests made demonstrate effectiveness method. © 2011 Wiley Periodicals,...

Leukocyte transendothelial migration is a key step in their recruitment to sites of inflammation. However, synergic regulation endothelium-expressed selectins on leukocyte transmigration remains unclear. In this study, an vitro model was developed investigate the dynamic contributions P- and E-selectin polymorphonuclear neutrophil (PMN) under static conditions. Human umbilical vein endothelial cells (HUVECs) were treated with LPS for 4 or 12 h induce different expression intercellular...

We investigate the concentration instabilities that arise in vertical dense particulate flows during hydraulic conveying, where widely used two-fluid model is employed. Results show system exhibits instability across a broad spectrum of controlling parameters. also obtain fully nonlinear transient numerical solution for by using finite difference method. It found small disturbances transform into saturation waves with amplitudes when effect becomes dominant, which corresponds to plug flow or...

Abstract Submarine groundwater discharge (SGD) has been widely recognized as an important source of dissolved nutrients in coastal waters and affects nutrient biogeochemistry. In contrast, little information is available on SGD impacts carbon budgets. Here, we assessed the associated (dissolved inorganic [DIC] total alkalinity [TA]) fluxes Liaodong Bay (the largest bay Bohai Sea, China) discussed their border implications for DIC budget buffering capacity. Based 223 Ra 228 mass balance...

Enhanced oil recovery draws increasingly interests from the research and development phases to oilfield implementation worldwide. Due complexity of developed reservoirs requirement carbon footprint reduction, new innovations are urgently needed increase enhanced efficiency and/or reduce emissions simultane- ously. This paper presents strategies improve performance dioxide flooding, polymer flooding imbibition in complex reservoirs. Field trials conducted at Mahu demonstrated potential...