Sanduni Amaya Abeydeera

ORCID: 0000-0003-4503-1671
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About
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Research Areas
  • Testicular diseases and treatments
  • Sperm and Testicular Function
  • Cell death mechanisms and regulation
  • Sexual Differentiation and Disorders
  • Urological Disorders and Treatments
  • RNA Interference and Gene Delivery
  • Reproductive Biology and Fertility

Royal Children's Hospital
2020

Murdoch Children's Research Institute
2019-2020

During early testicular development, neonatal gonocytes transform into spermatogonial stem cells (SSC), and any untransformed are thought to undergo apoptosis. In human cryptorchidism, persisting may lead seminoma. Using Bcl2-associated X knockout (BAXKO) mice, we investigated apoptosis in gonocyte development during mouse minipuberty. Testes from BAXKO, heterozygous (HET), wild-type (WT) littermates were collected on postnatal days 1, 3, 6, 9 (<i>n</i> = 6/group), labelled with...

10.1159/000508567 article EN Sexual Development 2019-01-01

10.1159/000512412 article CA Sexual Development 2019-01-01
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