A5040423204- Reproductive System and Pregnancy
- Monoclonal and Polyclonal Antibodies Research
- Endometriosis Research and Treatment
- Mesenchymal stem cell research
- Immunotherapy and Immune Responses
- Tissue Engineering and Regenerative Medicine
- Multicomponent Synthesis of Heterocycles
- Glycosylation and Glycoproteins Research
- Immune Cell Function and Interaction
- Pregnancy and preeclampsia studies
- Reproductive Biology and Fertility
- T-cell and B-cell Immunology
- SARS-CoV-2 and COVID-19 Research
- Pregnancy and Medication Impact
- Kruppel-like factors research
- Pluripotent Stem Cells Research
- Brucella: diagnosis, epidemiology, treatment
- Renal and related cancers
- Nanoparticle-Based Drug Delivery
- Cancer Cells and Metastasis
- Electrospun Nanofibers in Biomedical Applications
- Uterine Myomas and Treatments
- Sperm and Testicular Function
- Protein purification and stability
- Galectins and Cancer Biology
Academic Center for Education, Culture and Research
2016-2025
Tehran University of Medical Sciences
2016-2025
Royan Institute
2015-2025
Biotechnology Research Center
2009-2024
Iran University of Medical Sciences
2012-2021
Varta Micro Innovation (Austria)
2018
University of Tehran
2017
University of Kashan
2015
Shahid Beheshti University of Medical Sciences
2015
Islamic Azad University, Omidieh Branch
2013
The transition from oviparity to viviparity and the establishment of feto-maternal communications introduced placenta as major anatomical site provide nutrients, gases, hormones developing fetus. has endocrine functions, orchestrates maternal adaptations pregnancy at different periods pregnancy, acts a selective barrier minimize exposure fetus xenobiotics, pathogens, parasites. Despite fact that this ancient organ is central for normal in eutherians, remains one least studied organs. first...
Endometriosis is a chronic, painful, and inflammatory disease characterized by extra-uterine growth of endometrial tissues. Increased angiogenesis resistance to apoptosis have been suggested be involved in pathogenesis development endometriosis. The objective this study was examine potential contribution eutopic (EuESCs) ectopic (EESCs) stromal cells patients with endometriosis compared from non-endometriotic controls (CESCs).Stromal were isolated enzymatic digestion (n = 11) 17) tissues...
In recent decades, stem cell therapy has been introduced as a novel therapeutic approach for patients suffering from bone disorders. Recently, menstrual blood identified an easily accessible and recycled source. However, the osteogenic differentiation capacity of blood-derived cells (MenSCs) compared with other adult remained unsolved. The aim this study was to investigate MenSCs marrow-derived mesenchymal (BMSCs) in presence human platelet releasate (HPR). Our results showed that were...
Citation Jeddi‐Tehrani M, Torabi R, Zarnani AH, Mohammadzadeh A, Arefi S, Zeraati H, Akhondi MM, Chamani‐Tabriz L, Idali F, Emami Zarei S. Analysis of plasminogen activator inhibitor‐1, integrin beta3, beta fibrinogen and methylenetetrahydrofolate reductase polymorphisms in Iranian women with recurrent pregnancy loss. Am J Reprod Immunol 2011; 66: 149–156 Problem To identify the associations inhibitor‐1 (PAI‐1) −675 4G/5G, (BF) −455G/A, 3 (ITGB3) 1565T/C, (MTHFR) 677C/T 1298A/C loss (RPL)....
Evidence of germ cell derivation from embryonic and somatic stem cells provides an in vitro model for the study development, associated epigenetic modification mammalian gametogenesis. More importantly, derived gametes also represent a potential strategy treating infertility. In mammals, male female gametes, oocyte sperm, are specific population, PGCs (primordial cells) that segregate early embryogenesis. We have isolated pluripotent SSEA-1+ (stage-specific antigen-1+) mice bone marrow using...
Abstract Although natural killer (NK) cells play a crucial role in the maintenance of successful pregnancy, their cytotoxic activity should be tightly controlled. We hypothesized that endometrial mesenchymal stromal/stem (eMSCs) could potentially attenuate functional features NK cells. Herein, we assessed immunomodulatory effects menstrual blood-derived (MenSCs), as surrogate for eMSCs, on function. Our results showed MenSCs induced proliferation However, IFN-γ/IL-1β pretreated significantly...
Menstrual blood has been introduced as an easily accessible and refreshing stem cell source with no ethical consideration. Although recent works have shown that menstrual cells (MenSCs) possess multi lineage differentiation capacity, their efficiency of hepatic in comparison to other resources not addressed so far. The aim this study was investigate capacity MenSCs compared bone marrow-derived (BMSCs) under protocols developed by different concentrations hepatocyte growth factor (HGF)...
In recent years, the advantages of menstrual blood-derived stem cells (MenSCs), such as minimal ethical considerations, easy access and high proliferative ability, have inspired scientists to investigate potential MenSCs in cell therapy different diseases. order characterize potency these for future liver diseases, we examined differentiate into hepatocytes, using protocols. First, immunophenotyping properties osteoblasts, adipocytes chondrocytes were evaluated. Thereafter, differentiation...
Abstract Aim: Menstrual blood stromal stem cells (MBSCs) have been demonstrated to exhibit cell properties such as the capability for self‐renewal and multipotency, allowing multilineage differentiation. In addition, this type has various immunomodulatory effects. study, we examined potential effect of MBSCs on proliferation peripheral mononuclear (PBMCs) in allogeneic mixed lymphocyte reaction (MLR). Materials Methods: was collected from healthy donors after menstrual flow initiated its...
Introduction The recent identification of menstrual blood-derived stem cells (MenSCs) as a unique population has created enormous promise for tissue engineering. In this study, after characterization MenSCs in comparison with bone marrow-derived (BMSCs), the potential seeded into electrospun, biodegradable, nanofibrous scaffolds order to engineer cartilage was evaluated. Methods and BMSCs were isolated by discontinuous density gradient centrifugation plastic adherence. After compared BMSCs,...