A5100372425- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Nanoplatforms for cancer theranostics
- Hepatocellular Carcinoma Treatment and Prognosis
- Pediatric Hepatobiliary Diseases and Treatments
- Genital Health and Disease
- Spectroscopy Techniques in Biomedical and Chemical Research
- Infectious Diseases and Tuberculosis
- Cancer Mechanisms and Therapy
- Radiomics and Machine Learning in Medical Imaging
- Parathyroid Disorders and Treatments
- Cancer-related molecular mechanisms research
- Generative Adversarial Networks and Image Synthesis
- Meningioma and schwannoma management
- Photodynamic Therapy Research Studies
- Gout, Hyperuricemia, Uric Acid
- Teratomas and Epidermoid Cysts
- Salivary Gland Tumors Diagnosis and Treatment
- Calibration and Measurement Techniques
- Head and Neck Anomalies
- Fashion and Cultural Textiles
- Case Reports on Hematomas
- Drug Transport and Resistance Mechanisms
- Diphtheria, Corynebacterium, and Tetanus
- Liver physiology and pathology
Mengchao Hepatobiliary Hospital
2022-2023
Fujian Medical University
2022-2023
Kunming Medical University
2022
Alibaba Group (United States)
2022
Chengdu Third People's Hospital
2021
William Beaumont Army Medical Center
2018
University of Pennsylvania
1996
Intrahepatic cholangiocarcinoma (iCCA) can originate from the large bile duct group (segment ducts and area ducts), small (septal interlobular terminal (bile ductules canals of Hering) intrahepatic biliary tree, which be histopathological corresponding to type iCCA, iCCA with ductal plate malformation pattern, cholangiolocarcinoma, respectively. The challenge in pathological diagnosis above subtypes falls distinction cellular morphologies, tissue structures, growth patterns, invasive...
Abstract Objective . To evaluate the utility of polymerase chain reaction (PCR) amplification in detecting DNA from venereal‐associated microorganisms synovial fluid patients with inflammatory arthritis. Methods Oligonucleotide primers were developed for nested PCR based on Chlamydia, Ureaplasma , and Neisseria sequences. products detected by gel electrophoresis dot‐blot hybridization. Primers specific target bacterial used to search 61 specimens arthritis, including several clinically...
Mueller matrix imaging contains abundant biological microstructure information and has shown promising potential in clinical applications. Compared with the ordinary unpolarized light microscopy that relies on spatial resolution to reveal detailed histological features, encodes rich microstructures even at low-resolution wide-field conditions. Accurate staging of liver fibrosis is essential for therapeutic diagnosis prognosis chronic diseases. In clinic, pathologists commonly use...
Abstract Given that chemotherapy as a stand-alone therapeutic strategy may not be sufficient to effectively treat cancer, there is increasing interest in combination of and alternative therapies. Photodynamic therapy has the advantages high selectivity low side effects, so photodynamic become one most appealing strategies for tumor treatment. In this work, we constructed nano drug codelivery system (PPDC) realize combined treatment through encapsulating chemotherapeutic dihydroartemisinin...
Dihydroartemisinin (DHA), a widely used antimalarial agent, has clinical potential for the treatment of hepatic carcinoma. Although chemotherapy is indispensable tumor therapy, it generally limited by poor solubility, low efficiency, rapid clearance, and side effects. As an emerging method, photothermal therapy (PTT) many outstanding properties, but suffers from photostability photosensitizer incomplete ablation. Multimodal therapies could combine advantages different methods to improve...
Precise classification of mass-forming intrahepatic cholangiocarcinoma (MF-ICC) and hepatocellular carcinoma (HCC) based on magnetic resonance imaging (MRI) is crucial for personalized treatment strategy. The purpose the present study was to differentiate MF-ICC from HCC applying a novel deep-learning-based workflow with stronger feature extraction ability fusion capability improve performance deep learning small datasets.To retain more effective lesion features, we propose preprocessing...
We report on a metal–organic framework-based biomimetic cascade bioreactor for efficient treatment of hyperuricemia with low side effects.
Intrahepatic cholangiocarcinoma (ICC) can be divided into two morphological subtypes: large duct type and small ICC. This study aims to verify the feasibility of classification criteria clinicopathological characteristics ICC.ICC patients were ICC by immunohistochemical patterns. Subsequently, data groups was compared multivariate COX regression used clinical significance subtypes. In addition, IDH1/2 mutation, KRAS mutation FGFR2 translocation also evaluated.Totally, 32, 61 13 tumors...
Abstract Objective To evaluate the prognostic significance of microscopic bile duct invasion (MiBDI) in hepatocellular carcinoma (HCC) following R0 resection. Patients and Methods who underwent resection for HCC at nine medical centers were stratified into five groups: neither nor vascular (MiBDI−MVI−), alone (MiBDI+MVI−), both (MiBDI+MVI+), (MiBDI−MVI+), macroscopic (MaBDI). Overall survival (OS) was assessed using Kaplan–Meier analysis, independent risk factors OS determined Cox...
Thyroglossal duct cyst is a common congenital in the neck. The incidence of primary carcinoma thyroglossal less than 1% all age groups. We present case 63-year-old man with rapid expansion known mixed solid/cystic components. F-FDG PET/CT showed large anterior neck mass non-FDG-avid cystic component and hypermetabolic heterogeneous on right side confirmed by histopathology to be squamous cell carcinoma. Although rare, can assist evaluating extent malignant involvement
Abstract Background The effective method for predicting prognosis of ICC is still lack. This study aims to establish and verify an prognostic nomogram intrahepatic cholangiocarcinoma (ICC) after partial hepatectomy. Methods A model was developed in a cohort 127 patients from January 2015 December 2019. General clinical characteristics including preoperative physical examination data postoperative pathological features were obtained. independent risk factors identified by univariate...
Fashion is the form we express ourselves to world and has grown into one of largest industries in world. Despite significant evolvement fashion industry over past decades, it still a great challenge respond diverse preferences large number different consumers time accurately. To deal with problem, present an innovative demonstration trend-driven design system using deep generative modeling, which enables automatic editing based on trend reports. Our consists three components, including...
Abstract Background: Whipple's Disease (WD) is a rare infection caused by Tropheryma whipplei (TW), which affects multiple organs. When the invades respiratory system, severe failure can be induced. However, due to extremely low prevalence and insufficient awareness, disease easily ignored practitioners. Recently, we found case of pneumonia with TW We combined published cases perform retrospective analysis clinical features TW, intending provide reference for treatment WD.Methods: 11...