A5100669016- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Orthodontics and Dentofacial Orthopedics
- Periodontal Regeneration and Treatments
- Cleft Lip and Palate Research
- Dental materials and restorations
- Cancer-related molecular mechanisms research
- Reconstructive Surgery and Microvascular Techniques
- Craniofacial Disorders and Treatments
- dental development and anomalies
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Facial Trauma and Fracture Management
- Reconstructive Facial Surgery Techniques
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Bone Tissue Engineering Materials
- Tracheal and airway disorders
- Cancer-related gene regulation
- Ear and Head Tumors
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Renal Diseases and Glomerulopathies
- Medical Imaging and Analysis
Shanghai Jiao Tong University
2016-2025
Shanghai Ninth People's Hospital
2016-2025
National Clinical Research
2021-2025
Peking University Shenzhen Hospital
2016-2025
University of Hong Kong
2025
Stomatology Hospital
2025
National Clinical Research Center for Digestive Diseases
2021-2024
Shanghai Stomatological Hospital
2022-2024
Blackboard (United States)
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023
With the development of functional genomics studies, a mass long non-coding RNAs (LncRNA) were discovered from human genome. Long serve as pivotal regulators genes that are able to generate LncRNA-binding protein complexes modulate great number genes. Recently, LncRNA urothelial carcinoma-associated 1 (UCA1) has been revealed be dysregulated, which plays critical role in few cancers. However, biology and clinical significance UCA1 tumorigenesis oral squamous cell carcinoma (OSCC) remain...
To evaluate telescopic crown (TC), bar, and locator attachments used in removable four implant-supported overdentures for patients with edentulous maxillae.A total of 30 maxillary were enrolled a 3-year prospective study. Ten (group A) treated supported by TCs, 10 B) bar attachments, C) attachments. A 120 implants to restore oral function. During the follow-up period, implant survival success rates, biologic mechanical complications, prosthodontic maintenance efforts, patient satisfaction...
This in vitro study aims to evaluate the accuracy of dental implant placement by a novel image-guided hybrid robotic system for surgery (HRS-DIS).The HRS-DIS with 5 degree freedom (DOF) serial manipulator and 6 DOF Stewart platform was developed. To repeated drilling, holes were prepared twice 2.2 mm drill. placement, entry, exit angle deviations implants measured.Twenty-four twice, mean (±SD) diameters measured as ± 0.02 mm. A total 160 placed 32 phantoms HRS-DIS. The deviation 0.8 0.54 mm,...
Abstract Objective Defects of the maxilla caused by tumor resection create high levels psychological and physical trauma for patients. The application osseointegrated dental implants using either an obturator prosthesis or a free vascularized flap has tremendously changed retention stability superstructure. However, no study been performed to compare function aforementioned two approaches quality life subjective assessments Materials methods Eligible patients who were treated with maxillary...
Abstract Purpose: To evaluate the alterations of soft tissue around a single‐tooth implant in anterior maxilla with new defined pink esthetic score (PES) at time crown placement and 6 months post‐loading. Material methods: According to case inclusion criteria, 29 patients subjected replacement ITI implant‐supported restoration were included. Assessments after (baseline) (follow‐up) performed by two orthodontists PES. Results: No statistically significant difference was found between...
Abstract Purpose The purpose of this study was twofold: (i) to compare vertical bone height ( VBH ) after tumor resection through grafting with either a double‐barrel fibula DBF technique or distraction osteogenesis the VDOF ); (ii) performance loaded dental implants following special focus on implant survival, success, and resorption. Materials methods This retrospective clinical involved 19 patients who underwent placement (group A , n = 9) B 10) for mandibular reconstruction from M arch...
Oral squamous cell carcinoma (OSCC), the most common oral cancer, damages epithelial cells after accumulation of multiple genetic mutations. Although emerging evidence supports key role circular RNAs (circRNAs) in various malignancies, clinical value and function circRNAs OSCC remain unclear. In this study, patients with (n = 8) controls ( n were compared using high-throughput sequencing microarray circRNA expression profiles. The hsa_circ_0007059 was downregulated OSCC. Subsequently, levels...
Abstract Background Static computer‐assisted surgery (s‐CAIS) and dynamic implant (d‐CAIS) are the main digital approaches in guiding dental placement. Purpose The aim of this study was to explore compare learning curves for s‐CAIS d‐CAIS by beginners. Materials Methods Three students used each model drilling five positions with missing teeth. Operators performed test sets models an interval 7 ± 1 days assisted system. After a six‐month break, same again way but A total thirty were used, 150...
Abstract Introduction The objective of the study was to provide long‐term clinical outcomes and complications in severely atrophic edentulous maxillae treated by means quad zygoma protocol (QZP) using Anatomy‐Guided Approach (AGA). Methods This a retrospective cohort all consecutive patients with maxilla insufficient bone height width anterior posterior regions bilaterally, who underwent rehabilitation QZP between May 2006 December 2021. All were followed for at least 1 year. zygomatic...
ABSTRACT Objectives To evaluate the feasibility of esthetic assessments based on intraoral scanning data using pink and white scores (PES/WES). Materials Methods Thirty samples with both photographs were collected rated by two observers excellent consistency independently. PES includes seven variables, WES five. The maximum 14 10, respectively. Results mean PES/WES was 10.60 ± 1.69 8.50 1.28 for 10.97 8.40 1.25 data. No significant difference observed between sample types. alveolar process...
Abstract Purpose This study aimed to compare the accuracy of immediate implant placement (IIP) with different macrogeometry using a dynamic navigation in maxillary aesthetic zone. Methods Seventy-six extraction sockets zone from nineteen partially edentulous models were randomly divided into four system groups macrogeometry: non-progressive and trapezoidal (NP-T), progressive (P-T), V-shaped (P-V), spiral (P-S). The coronal, apical, angular deviations fully guided implants measured compared...
Abstract Purpose The aim of this retrospective case–control study was to evaluate the intermediate long‐term clinical performance and success rate dental implants inserted into sites previous early implant failure. Material methods A evaluation conducted on 6456 patients with 10,234 from J anuary 2004 D ecember 2011. failure retreated in failed were enrolled study. collected data included patient′s characteristics, characteristics (failed replaced), if case, any additional surgery performed...
Background . Circular RNAs (circRNAs) are a type of covalently closed loop structure endogenous RNAs. Recent studies have shown that circular may play an important role in human cancer. However, there is limited information on the function circRNA oral squamous cell carcinoma (OSCC). Methods Hsa_circ_001242 expression levels 40 paired OSCC tissues and four lines were selected using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR). A receiver operating...
Circular RNA (circRNA) is a type of non-coding molecule that affects the cellular regulatory network by sequestering microRNA (miRNA) like sponge. This study was performed to identify differentially-expressed circRNA in oral squamous cell carcinomas (OSCCs). By high-throughput sequencing, microarray expression profiles were acquired from patients with OSCCs (n[Please check this retains your intended meaning.]=8) and controls (n=8), which totaled 1921 existing molecules[Please meaning. itself...
The purpose of this 2-year randomized controlled clinical trial was to assess the differences in implant survival rates, soft tissue preservation, patient centered outcome and crestal bone changes applying minimally invasive (MI) flapless approach for single placement compared flapped surgery (FS).Subjects eligible study were randomly assigned into two groups: MI or FS. Items evaluation following: installation position, healing, post-surgical pain, outcome, marginal loss (MBL), rate.Forty...