A5101743100- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Bioinformatics and Genomic Networks
- Plant nutrient uptake and metabolism
- Plant Micronutrient Interactions and Effects
- RNA modifications and cancer
- MicroRNA in disease regulation
- Rice Cultivation and Yield Improvement
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Clostridium difficile and Clostridium perfringens research
- Angiogenesis and VEGF in Cancer
- Cellular Mechanics and Interactions
- Nutritional Studies and Diet
- Amyotrophic Lateral Sclerosis Research
- Gene expression and cancer classification
- Multiple Sclerosis Research Studies
- RNA Research and Splicing
- Long-Term Effects of COVID-19
- S100 Proteins and Annexins
- Gut microbiota and health
Shenyang Agricultural University
2023-2024
Chengdu Medical College
2022-2023
Chengdu University
2022-2023
Saint-Petersburg State Agrarian University
2023
Zero to Three
2022
Peking University Shenzhen Hospital
2019-2021
Anhui Medical University
2020-2021
ORCID
2020-2021
Huashan Hospital
2020-2021
Fudan University
2020-2021
Oral squamous cell carcinoma (OSCC), the most common oral cancer, damages epithelial cells after accumulation of multiple genetic mutations. Although emerging evidence supports key role circular RNAs (circRNAs) in various malignancies, clinical value and function circRNAs OSCC remain unclear. In this study, patients with (n = 8) controls ( n were compared using high-throughput sequencing microarray circRNA expression profiles. The hsa_circ_0007059 was downregulated OSCC. Subsequently, levels...
Growing evidence has indicated that alterations in the gut microbiota and nutritional quality of dietary intake were associated with COVID-19. Whether these associations reflect causality is still unknown.We performed a two-sample Mendelian randomization analysis using genetic variants as instrumental variables for microbiota, component intake, COVID-19.We found Ruminococcustorques group genus was significantly The Ruminococcaceae UCG013 Ruminococcus1 suggestively Actinobacteria class,...
The coronavirus disease 2019 (COVID-19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID-19 may cause various neurologic symptoms, including cognitive impairment. We aimed to assess causal effect of neurodegenerative diseases using two-sample Mendelian randomization (MR) study.Genetic variants were obtained from genome-wide association studies (GWAS) summary-level data meta-analyses. used inverse variance-weighted (IVW)...
Increasing evidence suggests that circular RNAs (circRNAs) play a major role in tumorigenesis and cancer progression. This study aimed to identify aberrant expression of hsa_circ_0003829 oral squamous cell carcinoma (OSCC) explore its clinical significance.We conducted prospective examine the pattern 60 paired OSCC normal samples lines using real-time quantitative polymerase chain reaction. We also evaluated diagnostic value based on receiver operating characteristic (ROC) curve analysis,...
Contactin 3 (CNTN3) is a member of the contactin family that primarily expressed in nervous system. However, to best our knowledge, expression and its role development progression brain tumours has not been studied. Although glioblastoma multiforme (GBM) most common malignant tumour, advances therapeutic options for patients with GBM have modest due an incomplete understanding molecular mechanisms underlying progression. The aim present study was examine correlation between CNTN3 associated...
Abstract Background Monosaccharide transporter (MST) family, as a carrier for monosaccharide transport, plays an important role in carbon partitioning and widely involves plant growth development, stress response, signaling transduction. However, little information on the MST family genes is reported maize ( Zea mays ), especially response to abiotic stresses. In this study, genome-wide identification of was performed maize. Result A total sixty-six putative members gene were identified...
As a novel class of endogenous ncRNAs, Circular RNAs (circRNAs) have been verified to be involved in the carcinogenesis and tumor progression.This study aimed investigate potential function candidate circRNA hsa_circ_0036988 oral squamous cell carcinoma (OSCC).The altered expression was validated by quantitative real-time polymerase chain reaction (qRT-PCR) OSCC samples lines. The associations between levels clinicopathological features were statistically analysed. evaluated via series vitro...
Abstract BackgroundBreast cancer is the most common malignant tumor in women. Due to mechanism of breast has not yet been completely clear, we aim identify key pathway and genes based on bioinformatics method. MethodsThe samples were obtained from NCBI-GEO website. Then, GEO2R tools Venn diagram software used differentially expressed (DEGs). Gene enrichment analysis was performed by ClusterProfiler package (version 3.16.1) R. The protein-protein interaction (PPI) network plotted Search Tool...
Abstract Background Monosaccharide transporter (MST) family, as a carrier for monosaccharide transport, plays an important role in carbon partitioning and widely involves plant growth development, stress response, signaling transduction. However, little information on the MST family genes is reported maize ( Zea mays ), especially response to abiotic stresses. In this study, genome-wide identification of was performed maize. Result A total sixty-six putative members gene were identified...
Abstract Purpose: Breast cancer (BC) is the most common malignant tumor in women. Due to mechanism of BC has not yet been completely clear, we aim identify key pathway and genes based on bioinformatics method. Methods: Samples were obtained from NCBI-GEO website. Then, GEO2R tools Venn diagram software used differentially expressed (DEGs). Next, analyze Kyoto Encyclopedia Gene Genome (KEGG) gene ontology (GO) analyzed by Database for Annotation, Visualization Integrated Discovery (DAVID)....
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with an extremely poor prognosis and high mortality rate. Genome-wide studies have shown that the SLIT/ROBO signaling pathway plays important role in pancreatic tumor development progression. However, effect mechanism of ROBO2 progression cancer remains largely unknown. Methods In this study, real-time polymerase chain reaction (RT-PCR) western blot analyses were adopted to evaluate expression level proteins...