A5064971552- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Epigenetics and DNA Methylation
- PI3K/AKT/mTOR signaling in cancer
- Liver Disease Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- MicroRNA in disease regulation
- Plant nutrient uptake and metabolism
- Marine animal studies overview
- Antimicrobial Resistance in Staphylococcus
- Liver Disease and Transplantation
- Microbial infections and disease research
- Tryptophan and brain disorders
- Clostridium difficile and Clostridium perfringens research
- Liver physiology and pathology
- Cancer, Hypoxia, and Metabolism
- Cancer-related cognitive impairment studies
- Diet, Metabolism, and Disease
- Neonatal Respiratory Health Research
- Clinical Nutrition and Gastroenterology
- Tracheal and airway disorders
- Virus-based gene therapy research
- Drug-Induced Hepatotoxicity and Protection
- Animal Virus Infections Studies
- Genetic Syndromes and Imprinting
Chonnam National University
2012-2024
University of Ulsan
2014-2016
Asan Medical Center
2014-2016
Ulsan College
2014-2016
Drug-induced liver injury (DILI) is a significant threat to patient health and major concern during drug development.Recently, multiple circulating microRNAs (miRNAs) have been reported be potential biomarkers for DILI.To adapt validate miRNAs clinical use, we investigated the time-course changes in miR-122 expression levels an acetaminophen-induced model rats.In addition, miR-155 miR-21 were evaluated as makers of inflammation regeneration, respectively, characterize status.Our results...
Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, on development and recurrence hepatocellular carcinoma (HCC) were investigated using diethylnitrosamine (DEN)‑induced rat model HCC. Tumor foci characterized by gross examination histopathological characteristics, including proliferation, hepatic progenitor cell content expression hepatocarcinoma‑specific molecular markers. Potential target molecules to determine...
Current studies report that aberrations in epigenetic regulators or chromatin modifications are related to tumor development and maintenance. EZH2 (Enhancer of zeste homolog 2) is one the catalytic subunits Polycomb repressive complex 2, a crucial regulator. has master regulatory function such processes as cell proliferation, stem differentiation, early embryogenesis. In humans, linked oncogenic several carcinomas, including breast cancer, dysregulation been particularly associated with loss...
Various viral and bacterial pathogens interact with environmental factors to cause diarrhea in piglets. Enterococcus spp. are Gram-positive anaerobic bacteria that commonly found the gastrointestinal tract of several animal species, including pigs. have been reported infect species as a pathogen. However, infection by hirae is rare pigs; only few cases worldwide. Four piglets were examined diagnostic laboratory Optipharm Inc. (Cheongju, Korea). During initial post-mortem examination, no...
Porcine epidemic diarrhea virus (PEDV) binds to particular cell surface receptors penetrate cells. The specifically identifies certain carbohydrate structures present on the of facilitate binding process. Nevertheless, influence viral infections specific alterations glycoconjugates in small intestines remains unexplored.
The olfactory mucosa (OM) is crucial for odorant perception in the main system. terminal carbohydrates of glycoconjugates influence chemoreception epithelium (OE).The histological characteristics and glycoconjugate composition OM Korean native cattle (Hanwoo, Bos taurus coreae) were examined to characterize their morphology possible functions during postnatal development.The neonate adult was evaluated using histological, immunohistochemical, lectin histochemical methods.Histologically, both...
The vomeronasal organ (VNO) is critical for reproduction and social behavior in ruminants, including cattle.The present study examined the structure of VNO its epithelial cells neonatal adult Korean native cattle (Hanwoo), Bos taurus coreanae, using immunohistochemistry lectin histochemistry.Histologically, comprised two types epithelia: medial sensory (VSE) lateral non-sensory epithelia (VNSE).Numerous blood vessels nerve bundles were observed within cartilage encased lamina...