A5021108291- RNA modifications and cancer
- Head and Neck Cancer Studies
- Viral-associated cancers and disorders
- Radiomics and Machine Learning in Medical Imaging
- Histone Deacetylase Inhibitors Research
- Epigenetics and DNA Methylation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- MRI in cancer diagnosis
Sun Yat-sen University
2019-2023
Sun Yat-sen University Cancer Center
2019-2023
Aim: The present study aimed to evaluate the combined value of locoregional extension patterns (LEPs) and circulating cell-free Epstein–Barr virus (cf EBV) DNA for risk stratification locoregionally advanced nasopharyngeal carcinoma (LA-NPC) better guide therapeutic strategies. Methods: A total 7227 cases LA-NPC were reviewed retrospectively classified into six groups according their LEP (ascending, descending, or mixed type) pre-treatment cf EBV-DNA load (⩾ versus <4000 copy/ml). Using a...
Presently, there is a lack of effective blood-based biomarkers facilitating the diagnosis hepatocellular carcinoma (HCC). Thus, we aimed to investigate novel methylation markers for HCC diagnosis, and explore relationships between biomarker clinicopathology HCC. The status SCAN domain containing three (SCAND3) myosin 1g (Myo1g) genes in cell lines tissues were detected by digital droplet PCR. serum SCAND3 Myo1g levels analyzed HCC-afflicted patients unafflicted controls. results indicated...
Abstract Background Cysteine dioxygenase 1 (CDO1) is frequently methylated, and its expression decreased in many human cancers including breast cancer (BC). However, the functional mechanistic aspects of CDO1 inactivation BC are poorly understood, diagnostic significance serum methylation remains unclear. Methods We performed bioinformatics analysis publicly available databases employed MassARRAY EpiTYPER sequencing technology to identify differentially methylated sites promoter tissues...