A5091627011- Reproductive Health and Contraception
- Global Maternal and Child Health
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Maternal and fetal healthcare
- Healthcare Policy and Management
- Reproductive Health and Technologies
- Gynecological conditions and treatments
- Global Health Care Issues
- Blood groups and transfusion
- Menstrual Health and Disorders
- Hepatitis B Virus Studies
- Cystic Fibrosis Research Advances
- Ovarian function and disorders
- Ectopic Pregnancy Diagnosis and Management
- Viral gastroenteritis research and epidemiology
- Maternal Mental Health During Pregnancy and Postpartum
- Chemical Reactions and Isotopes
- Sex and Gender in Healthcare
- Economic and Environmental Valuation
- Respiratory and Cough-Related Research
- Tracheal and airway disorders
- Hemoglobinopathies and Related Disorders
- Medical and Biological Ozone Research
Bayer (Germany)
2012-2023
Bielefeld University
2011
Bayer (United States)
2010
United BioSource Corporation (United Kingdom)
2010
Bayer (Canada)
2010
Oregon Health & Science University
2010
Rationale: Exacerbations are key events in the natural history of bronchiectasis, but clinical predictors and outcomes patients with frequently exacerbating disease not well described.Objectives: To establish if there is a “frequent exacerbator phenotype” bronchiectasis impact exacerbations on long-term outcomes.Methods: We studied enrolled from 10 centers Europe Israel, up to 5 years follow-up. Patients were categorized by baseline exacerbation frequency (zero, one, two, or three more per...
We explored the effects of premenstrual symptoms in women suffering from moderate-to-severe syndrome/premenstrual dysphoric disorder (PMS/PMDD) on work productivity, absenteeism, and daily life activities a large, worldwide exploratory study. Women aged 15–45 years 19 countries North America, Latin Europe, Asia, Australia were screened for suspected PMS PMDD invited to participate this 2-month web-based survey. Overall, 4,032 completed all administered questionnaires represent analysis set....
Objectives The objective of this study was to quantify the cost burden unintended pregnancies (UPs) in Norway, and estimate proportion costs due imperfect contraceptive adherence. Potential savings that could arise from increased uptake long-acting reversible contraception (LARC) were also investigated. Methods An economic model constructed total number UPs associated women aged 15–24 years. Adherence-related UP estimated using ‘perfect use’ ‘typical failure rates. use LARC projected by...
Purpose The purpose of this study was to determine the continuation rates new users long-acting reversible contraceptive (LARC) methods in UK, using data from general practice. Methods We conducted an observational a practitioner (GP) database, Health Improvement Network (THIN). studied were copper intrauterine devices (Cu-IUDs), levonorgestrel-releasing system (LNG-IUS), progestogen-only implants and injections. population comprised women THIN aged 18–44 years during period 2004–2009 who...
The purpose of this study was to quantify the impact estradiol-valerate/dienogest (E(2)V/DNG; Qlaira(®)/Natazia(®)) on work productivity and activities daily living in European Australian women with heavy menstrual bleeding.Women aged 18-54 years a confirmed diagnosis bleeding no recognizable pathology were recruited across nine countries (the Czech Republic, Finland, Germany, Hungary, Netherlands, Poland, Sweden, UK, Ukraine) Australia. randomized receive either E(2)V/DNG (n = 149) or...
Objective The aim of the study was to estimate burden and direct medical costs unintended pregnancy public payer in Spain.
Objectives To determine the use of long-acting reversible contraceptives (LARCs) in UK over period 2004 to 2010, using general practice database The Health Improvement Network (THIN).Methods Women THIN, aged 18 44 years during who had been registered with their practitioner for at least five years, a prescription history one year were included. THIN was searched Read and MULTILEX codes for: copper intrauterine devices (Cu-IUDs), levonorgestrel releasing-intrauterine system (LNG-IUS),...
Objectives: To quantify the change in work productivity and activities of daily living North American women with heavy menstrual bleeding (HMB) treated estradiol valerate/dienogest (E2V/DNG; Qlaira®/Natazia®) compared to placebo. Methods: Women United States Canada, aged 20–53 years an objective diagnosis HMB no recognizable anatomical pathology, were E2V/DNG or placebo for seven cycles (196 days). Main outcome measures included (i.e., while at work) measured using a modified Work...
Abstract Objective To evaluate the cost‐effectiveness of a novel intrauterine system, levonorgestrel system 13.5 mg vs. oral contraception, in women at risk unintended pregnancy. Design Cost‐effectiveness model using efficacy and discontinuation data from published articles. Setting Societal perspective including direct indirect costs. Population Women pregnancy reversible contraception. Methods An economic analysis was conducted by modeling different health states contraception over 3‐year...
To combine results from a randomized controlled study (RCT) and an observational (OS) to evaluate discontinuation rate of levonorgestrel-containing intrauterine contraceptive device (LNG IUD) in real-life setting. We included 253 parous nulliparous women aged 21–40 years our own phase II RCT. A total 1607 all ages (including adolescents, < 20 years) were recruited OS. applied the cross design synthesis (CDS) method recommended by United States General Accounting Office. This combines...
To evaluate the psychometric and measurement properties of two patient-reported outcome instruments, menstrual pictogram superabsorbent polymer-containing version 3 (MP SAP-c v3) Uterine Fibroid Daily Bleeding Diary (UF-DBD). Test-retest reliability, criterion, construct validity, responsiveness, missingness comparability MP v3 UF-DBD versus alkaline hematin (AH) method a patient global impression severity (PGI-S) were analyzed in post hoc trial analyses.Analyses based on data from up to 756...