A5090534485- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Urticaria and Related Conditions
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune Bullous Skin Diseases
- Sphingolipid Metabolism and Signaling
- Trace Elements in Health
- Eosinophilic Disorders and Syndromes
- Cancer and Skin Lesions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Salivary Gland Tumors Diagnosis and Treatment
- Soft tissue tumor case studies
- Ear and Head Tumors
- Endoplasmic Reticulum Stress and Disease
- Peptidase Inhibition and Analysis
- Otitis Media and Relapsing Polychondritis
- PI3K/AKT/mTOR signaling in cancer
- Celiac Disease Research and Management
- Genital Health and Disease
- Cervical Cancer and HPV Research
- Cutaneous lymphoproliferative disorders research
- Colorectal and Anal Carcinomas
- Contact Dermatitis and Allergies
- Vascular Anomalies and Treatments
Gifu University
2013-2025
Gifu Municipal Hospital
2016
Gifu Prefectural General Medical Center
2007
Reactive oxygen species (ROS) are involved in the pathogenesis of generalised pustular psoriasis (GPP), but this involvement has not been fully elucidated. We performed diacron-reactive metabolite (d-ROM) test and biological antioxidant potential (BAP) on sera from nine patients with active GPP who were hospitalised treated at our hospital, including three pregnancy (PPP). The serum d-ROM BAP levels evaluated before treatment 1 month treatment. also immunostaining 4-hydroxy-2-nonenal (4-HNE)...
Sphingosine kinase (SK), a key enzyme in sphingosine-1-phosphate (S1P) synthesis, is known to be overexpressed various types of cancer cells. The effects anticancer agents on SK1/S1P signaling have not yet been fully assessed melanoma In the present study, we investigated combination FTY720, an S1P receptor antagonist, and cisplatin, DNA-damaging agent, induction death human cells, as well molecular mechanisms involved. viability cell lines was examined following treatment with drugs....
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome has recently been described as an autoinflammatory disease associated with severe adult-onset inflammatory manifestations. The various clinical manifestations include recurrent high-grade fever, neutrophilic dermatoses, cutaneous vasculitis, chondritis of the ear and nose, pulmonary infiltrates, cytopenia, uveitis, gastrointestinal pain or inflammation, aortitis, hepatosplenomegaly, hematological disorders. is caused...
Abstract Palmoplantar pustulosis ( PPP ) is characterized by neutrophilic pustules with erythema, which are limited to the hands and feet. Although granulocyte monocyte adsorption apheresis GMA has shown remarkable effects on generalized pustular psoriasis, there few reports of treated . We three refractory patients using weekly for 5 weeks. The skin eruptions were assessed a 5‐grade score scales, pustules, erythema. decreased total grade from 9 2 in 1 2, 7 3 patient 3. estimated be...
ROS are involved in the pathogenesis of bullous pemphigoid (BP), but this involvement has not been fully elucidated. In study, to further elucidate pathogenic role BP, we examined results diacron-reactive oxygen metabolite test and biological antioxidant potential for 16 patients with BP who visited our hospital before being treated systemic corticosteroids. average levels, expressed Carratelli units, were significantly reduced at 1 month treatment (from 335.6 ± 40.3 units 224.7 61.6
Cylindroma is a benign skin appendageal tumor arising from pluripotent stem cells in the follicle. Multiple cylindroma typically occurs as component of Brooke-Spiegler syndrome or only lesion familial cylindromatosis. We herein report an unusual case multiple involving trunk without any other features and no family history supporting possibility Immunohistochemical CYLD NF-κB, which are involved pathogenesis cylindroma, tumors also presented.