Inge Larsen

ORCID: 0000-0003-4575-2241
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About
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Research Areas
  • Animal Behavior and Welfare Studies
  • Animal Disease Management and Epidemiology
  • Microbial infections and disease research
  • Influenza Virus Research Studies
  • Veterinary medicine and infectious diseases
  • Antibiotic Resistance in Bacteria
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Animal Nutrition and Physiology
  • Aquaculture disease management and microbiota
  • Bioactive Compounds and Antitumor Agents
  • Respiratory viral infections research
  • COVID-19 and Mental Health
  • Animal Virus Infections Studies
  • Animal health and immunology
  • Humic Substances and Bio-Organic Studies
  • Clostridium difficile and Clostridium perfringens research
  • Escherichia coli research studies
  • Viral gastroenteritis research and epidemiology
  • Gut microbiota and health
  • Effects of Environmental Stressors on Livestock
  • Long-Term Effects of COVID-19
  • Antibiotics Pharmacokinetics and Efficacy
  • Viral Infections and Outbreaks Research
  • Parkinson's Disease and Spinal Disorders
  • Salmonella and Campylobacter epidemiology

University of Copenhagen
1993-2025

Knowledge Centre for Agriculture
2021

Larsen & Toubro (India)
2021

Arvid Nilssons Fond
2021

Abstract Background Umbilical outpouchings (UO) in pigs present a welfare concern because of ulceration risk and complications. Danish legislation requires with larger UOs to be housed sick pens soft bedding, some UO might not suited for transport. Because this, many are euthanized, adding the costs pig production. The true prevalence is unknown as no scientific reports randomly sampled herds exist. This study aimed estimate piglets weaners describe their clinical characteristics: size,...

10.1186/s40813-023-00352-8 article EN cc-by Porcine Health Management 2024-01-13

We investigated schoolteachers' emotional reactions to COVID-19 and mental health during three phases of the pandemic. further analyzed if teachers, who belonged a risk group, had more poorer than "non-risk" groups.We collected questionnaire data in May, June, November-December 2020 used from 2665 teachers at public schools (871 individuals participated all surveys). Participants reported their fear infection, transmission infection home or pupils, perceived burnout stress, worries about...

10.1007/s00420-021-01806-8 article EN other-oa International Archives of Occupational and Environmental Health 2021-10-18

A longitudinal study was performed in three Danish farrow to grower (30 kilos) herds over a 4-month period investigate the dynamics and clinical impacts of influenza virus (IAV) infections. In each herd, four batches consisting sows with five ear-tagged piglets were included. Nasal swabs and/or blood sampled from prior farrowing at weeks 1, 3, 5 end nursery period. Clinical examinations sampling time. The tested for IAV antibodies nasal samples, respectively. results revealed enzootically...

10.1186/s13567-019-0655-x article EN cc-by Veterinary Research 2019-05-22

We explored teachers' emotional reactions to the COVID-19 pandemic, and association between risk management these reactions.We used cross-sectional data from 2665 teachers working at public schools. Participants responded a questionnaire in May 2020. The analyses were adjusted for sex, age, cohabitation, region.Knowledge about adequate test behavior feeling secure regarding colleagues' actions hinder spread of virus associated with less frequent reactions. Lack access personal protective...

10.1097/jom.0000000000002136 article EN Journal of Occupational and Environmental Medicine 2021-01-05

Globally, the increase in antimicrobial resistance is of great concern. In Denmark, pig sector accountable for majority usage animals. As new-born piglets are at risk developing infectious omphalitis, and many pigs treated by antimicrobials within first days life, an early accurate diagnosis disease imperative to maintain animal welfare reduce usage. The aim present study was compare histopathological microbiological findings clinically diagnosed with without omphalitis during three after...

10.1186/s12917-025-04507-3 article EN cc-by-nc-nd BMC Veterinary Research 2025-02-08

The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that human virus strains. However, surveillance activities on swIAV have increased, more isolates characterized, revealing a high level genetic and differences even within the same lineage. objective this study was investigate one enzootically infected herd over year. Nasal swabs were collected monthly from sows (n = 4) piglets 40) farrowing unit, weaners 20) nursery....

10.3390/v12020248 article EN cc-by Viruses 2020-02-23

Abstract Antibiotics are widely used in pig farming across the world which has led to concerns about potential impact on human health through selection of antibiotic resistant pathogenic bacteria. This worry resulted development a production scheme known as pigs Raised Without (RWA), produced commercial farms, but ear-tagged RWA until slaughter unless they receive treatment, thus allowing farmer sell either premium priced or conventional meat. Development resistance been studied national...

10.1186/s42523-023-00258-4 article EN cc-by Animal Microbiome 2023-08-21

The aim of this study was to investigate the effect avoiding flock treatment on resistance levels in intestine pigs. To this, studies, each two pig herds, quantified resistant coliforms by culture method pigs treated as or individual animal treatments orally with neomycin against post-weaning diarrhea (PWD) intramuscularly amoxicillin prevent umbilical infection. Individual oral PWD did not lead a lower number proportion compared any herds under study, despite reduction incidences 32% and...

10.1093/lambio/ovaf008 article EN Letters in Applied Microbiology 2025-01-31

Lameness is a common clinical issue in gestating sows and leading cause for early culling antibiotic treatment. Diagnostic tools are limited, but acute phase proteins (APPs) could offer fast minimally invasive method optimizing The aim of this study was to investigate whether APP level measurements can be used as diagnostic tool, identify which major elevated lame sows. To determine this, blood samples were collected from the jugular vein 50 clinically healthy 12 conventional herds. analyzed...

10.3389/fvets.2025.1505132 article EN cc-by Frontiers in Veterinary Science 2025-02-19

ABSTRACT This study describes the results of a randomized clinical trial investigating effect oxytetracycline treatment dose and mode administration on selection antibiotic-resistant coliform bacteria in fecal samples from nursery pigs. Nursery pigs (pigs 4 to 7 weeks age) five pig herds were treated with for Lawsonia intracellularis -induced diarrhea. Each group was randomly allocated one groups: oral flock (i) high (20 mg/kg body weight), (ii) medium (10 mg/kg), or (iii) low (5 mg/kg)...

10.1128/aem.00538-17 article EN Applied and Environmental Microbiology 2017-04-08

Influenza A virus (IAV) is a highly contagious pathogen in pigs. Swine IAV (swIAV) infection causes respiratory disease and thereby challenge for animal health, welfare the production economy. In Europe, most widespread strategy controlling swIAV implementation of sow vaccination programs, to secure delivery protective maternally derived antibodies (MDAs) newborn piglets. this study we report unique case, where persistently (A/sw/Denmark/P5U4/2016(H1N1)) infected herd experienced an acute...

10.1371/journal.pone.0224854 article EN cc-by PLoS ONE 2019-11-14

To determine the genetic relatedness and presence of virulence antibiotic resistance genes in commensal Escherichia coli from nursery pigs Danish intensive production.The diversity 1000 E. strains randomly picked (N = 50 isolates) cultured faecal samples 4 pigs) five farms was analysed by repetitive extragenic palindromic-PCR (REP-PCR) 42 unique REP-profiles were detected (similarity <92%). One profile dominant (67.2% strains) but differed significantly coli: between eight 21 different...

10.1111/jam.12840 article EN Journal of Applied Microbiology 2015-05-12

Abstract Background The majority of antimicrobials given during the production pigs are to nursery pigs. influence antimicrobial use on levels resistant (AMR) genes is important quantify be able assess impact resistance food chain and risk human animal health. Results This study investigated response nine AMR five different treatment strategies with oxytetracycline, dynamics gene abundance over time by following 1167 from farms in Denmark. results showed no significant difference between...

10.1186/s12866-019-1619-z article EN cc-by BMC Microbiology 2019-12-01

Recent studies have questioned the effect of maternal derived antibodies (MDAs) to protect piglets against infection with influenza A virus (IAV). The lack protection IAV infections provided by MDAs has encouraged alternative vaccination strategies targeting young in an attempt stimulate early antibody response. There is a documenting efficacy piglet vaccination. In present study, we monitored group vaccinated and non-vaccinated Danish sow herd that initiated ¼ dose inactivated swine vaccine...

10.1016/j.rvsc.2019.10.015 article EN cc-by-nc-nd Research in Veterinary Science 2019-11-01

Umbilical outpouchings (UOs) are common in Danish pigs. Neonatal antibiotics therefore used with the hope of reducing umbilical infections and subsequently UOs. However, effect neonatal on preventing UO has been subject mixed conclusions, secondly, treating all animals might exacerbate development antimicrobial resistance. This study analysed effects different treatments prevalence mortality from birth to nursery unit. All treatment was day birth. The groups were: a negative control group,...

10.1186/s40813-024-00358-w article EN cc-by Porcine Health Management 2024-02-16

In Denmark, a Pure Pork concept for raising pigs without antibiotics was initiated in 2015 by the Danish Crown slaughterhouse cooperative. herds are characterised minimal use of and mainly treated individually. An increased prevalence suffering from umbilical outpouchings (UO) is considerable challenge producers. Umbilical challenging due to reduced welfare workload cost farmer. Therefore, producers require means other than antibiotic treatment prevent UO. The primary objective this study...

10.1016/j.prevetmed.2023.105905 article EN cc-by Preventive Veterinary Medicine 2023-03-22

Abstract Background Antibiotic (AB) consumption in production animals has a high awareness among politicians and consumers due to the risk of selection for AB resistance potentially zoonotic bacteria. However, treatment is at times necessary treat diseases ensure wellbeing we take into our care. Raised without antibiotics (RWA) concept where pigs are individually ear-tagged tracking, if treated, they lose their RWA status. At slaughter, farmer receives an additional price non-AB treated...

10.1186/s40813-021-00198-y article EN cc-by Porcine Health Management 2021-02-17

Aided by their advising veterinarians, pig producers need to make difficult decisions regarding herd health management strategies. For instance, the preventive use of antimicrobials and medicinal zinc oxide must be substituted with more sustainable approaches porcine post-weaning diarrhea. Veterinarians may find assistance in knowledge based on evidence this regard; however, overwhelming scientific literature is not always readily available. The overall aim paper suggest decision-support...

10.3390/ani12141737 article EN cc-by Animals 2022-07-06

Abstract Background Umbilical outpouchings (UO) are common in Danish weaners. In slaughter pigs UOs consist of various pathological diagnoses; however, no studies have assessed the pathology weaners from randomly selected herds, nor agreement between clinical examination findings and post-mortem results. The primary objective was to estimate prevalence UO-related before euthanasia pathologic macroscopic after euthanasia. A secondary assess size UO, presence ulcers, diagnosis Pigs were for...

10.1186/s40813-024-00401-w article EN cc-by Porcine Health Management 2024-11-22

Influenza A virus (IAV) in swine, so-called swine influenza (swIAV), causes respiratory illness pigs around the globe. In Danish pig herds, a H1N2 subtype named H1N2dk is one of main circulating swIAV. this cohort study, infection dynamic swIAV was evaluated herd by sampling and PCR testing from two weeks age until slaughter at 22 age. addition, next generation sequencing (NGS) used to identify characterize complete genome herd, examine antigenic variability sites hemagglutinin (HA)...

10.3390/v12091013 article EN cc-by Viruses 2020-09-10
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