A5079296976- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Virus-based gene therapy research
- Viral Infections and Immunology Research
- Veterinary medicine and infectious diseases
- Influenza Virus Research Studies
- Animal Behavior and Welfare Studies
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Plant Virus Research Studies
- T-cell and Retrovirus Studies
- Education, Healthcare and Sociology Research
- Aquaculture disease management and microbiota
- Viral Infectious Diseases and Gene Expression in Insects
- Animal Nutrition and Physiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Parasitic Infections and Diagnostics
- Indoor Air Quality and Microbial Exposure
- Pneumonia and Respiratory Infections
- Viral Infections and Outbreaks Research
- Bacillus and Francisella bacterial research
- Economic Analysis and Policy
- Dietetics, Nutrition, and Education
Danish Agriculture and Food Council
2012-2025
Knowledge Centre for Agriculture
2016-2025
University of Copenhagen
2020-2024
ICAR-National Research Centre on Pig
2020
Danish Meat Trade College
2008
Danish Cattle Research Centre
2004
Royal Agricultural University
2004
Abstract Background In a previous study, it was demonstrated that high replication of Porcine circovirus 2 (PCV2) in gnotobiotic pig correlated with the absence PCV2-neutralizing antibodies. The aim present study to investigate if this correlation could also be found SPF pigs which PMWS experimentally reproduced and naturally PMWS-affected pigs. Results When looking at total anti-PCV2 antibody titres, healthy animals seroconverted same time point, titres were only slightly lower compared...
Porcine reproductive and respiratory syndrome virus (PRRSV) is prevalent in Danish swine herds. In July 2019, PRRSV-1 was detected a PRRSV-negative boar station subsequently spread to more than 38 herds that had received semen from the station. Full genome sequencing revealed sequence of 15.098 nucleotides. Phylogenetic analyses showed strain recombination between Amervac (Unistrain PRRS vaccine; Hipra) 96V198 (Suvaxyn PRRS; Zoetis AH). The major parent spanned ORFs 1-2 part ORF 3 minor...
Abstract Background Umbilical outpouchings (UO) in pigs present a welfare concern because of ulceration risk and complications. Danish legislation requires with larger UOs to be housed sick pens soft bedding, some UO might not suited for transport. Because this, many are euthanized, adding the costs pig production. The true prevalence is unknown as no scientific reports randomly sampled herds exist. This study aimed estimate piglets weaners describe their clinical characteristics: size,...
A longitudinal study was performed in three Danish farrow to grower (30 kilos) herds over a 4-month period investigate the dynamics and clinical impacts of influenza virus (IAV) infections. In each herd, four batches consisting sows with five ear-tagged piglets were included. Nasal swabs and/or blood sampled from prior farrowing at weeks 1, 3, 5 end nursery period. Clinical examinations sampling time. The tested for IAV antibodies nasal samples, respectively. results revealed enzootically...
The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that human virus strains. However, surveillance activities on swIAV have increased, more isolates characterized, revealing a high level genetic and differences even within the same lineage. objective this study was investigate one enzootically infected herd over year. Nasal swabs were collected monthly from sows (n = 4) piglets 40) farrowing unit, weaners 20) nursery....
Porcine Reproductive and Respiratory Syndrome (PRRS) caused by the PRRS virus (PRRSV) is considered one of most devastating swine diseases worldwide. viruses are divided into two major genotypes, Type 1 2, with pronounced diversity between within genotypes. In Denmark more than 50% herds infected and/or 2 PRRSV. The main objective this study was to examine genetic drift in a population limited introduction new animals semen. A total 43 ORF5 42 ORF7 nucleotide sequences were obtained from...
Influenza A virus (IAV) is a highly contagious pathogen in pigs. Swine IAV (swIAV) infection causes respiratory disease and thereby challenge for animal health, welfare the production economy. In Europe, most widespread strategy controlling swIAV implementation of sow vaccination programs, to secure delivery protective maternally derived antibodies (MDAs) newborn piglets. this study we report unique case, where persistently (A/sw/Denmark/P5U4/2016(H1N1)) infected herd experienced an acute...
In recent years, it has become apparent that imbalances in the gastrointestinal system can impact organs beyond intestine such as lungs. Given established ability of probiotics to modulate immune by interacting with cells, our research aimed investigate whether administering probiotic strain Bacillus subtilis-597 could mitigate outcome influenza virus infection pigs. Pigs were fed a diet either or without B. for 14 days before being intranasally inoculated swine A H1N2 (1 C.2 lineage)....
The impact of different weaning strategies on the downstream circulation PRRSV has not been widely described. It is, however, believed that mixing pigs age groups is increasing risk in nursery section. In this study, were sampled three herds performed "mixed at (MIX)" and "all in/all out (AIAO)". MIX included holding underweighted piglets back containers for two weeks then move them to facilities with newly weaned from subsequent batches. Oral fluid samples collected four batches each herd,...
Transparent calculation methods are crucial when investigating trends in antimicrobial consumption over time and between populations. Until 2011, one single standardized method was applied quantifying the Danish pig with unit "Animal Daily Dose" (ADD). However, two new for assigning values ADDs have recently emerged, implemented by DANMAP, responsible publishing annual reports on consumption, Veterinary Food Administration (DVFA), Yellow Card initiative. In addition to ADD assignment...
The objective of the study was to compare responses pigs vaccinated with a PRRS MLV vaccine against PRRSV-1 or PRRSV-2 simultaneously both vaccines. Furthermore, efficacy two PRRSV vaccination strategies assessed following challenge. experimental design included four groups 4-weeks old SPF-pigs. On day 0 (DPV0), 1–3 (N = 18 per group) were modified live virus vaccines (MLV) containing (VAC-T1), (VAC-T2) (VAC-T1T2). One group left unvaccinated 12). DPV 62, from 1–4 mingled in new and...
Recent studies have questioned the effect of maternal derived antibodies (MDAs) to protect piglets against infection with influenza A virus (IAV). The lack protection IAV infections provided by MDAs has encouraged alternative vaccination strategies targeting young in an attempt stimulate early antibody response. There is a documenting efficacy piglet vaccination. In present study, we monitored group vaccinated and non-vaccinated Danish sow herd that initiated ¼ dose inactivated swine vaccine...
In July 2019, a PRRSV-negative boar station was infected with recombinant of two PRRSV vaccine strains, which subsequently spread to at least 36 herds that had received semen from the station. following months, all reported reduced productivity. The aim present study evaluate impact PRRS outbreak.Production data were collected 13 herds. average levels farrowings/week, liveborns/litter, stillborns/litter, pre-weaning mortality and weaned pigs/litter compared for five-month period after...
Infectious diseases are of great economic importance in commercial pig production, causing both clinical and subclinical disease, with influence on welfare, productivity, antibiotic use. The causes these often multifactorial laboratory diagnostics seldom routinely performed. aim the present study was to explore benefits monthly pathogen monitoring nursery finisher herds examine association between results observed signs, including coughing diarrhoea. Three samplings were conducted three...
Umbilical outpouchings (UOs) are common in Danish pigs. Neonatal antibiotics therefore used with the hope of reducing umbilical infections and subsequently UOs. However, effect neonatal on preventing UO has been subject mixed conclusions, secondly, treating all animals might exacerbate development antimicrobial resistance. This study analysed effects different treatments prevalence mortality from birth to nursery unit. All treatment was day birth. The groups were: a negative control group,...