Mariano Acosta

ORCID: 0000-0003-4582-5324
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About
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Research Areas
  • Analytical chemistry methods development
  • Electrochemical Analysis and Applications
  • Heavy Metal Exposure and Toxicity
  • Probiotics and Fermented Foods
  • Microbial Metabolites in Food Biotechnology
  • Tuberculosis Research and Epidemiology
  • Pesticide Residue Analysis and Safety
  • Bee Products Chemical Analysis
  • Mycobacterium research and diagnosis
  • Bacteriophages and microbial interactions
  • Insect and Pesticide Research
  • Trace Elements in Health
  • S100 Proteins and Annexins
  • Escherichia coli research studies
  • Heavy metals in environment
  • Neuroendocrine regulation and behavior
  • Antioxidant Activity and Oxidative Stress
  • Mercury impact and mitigation studies
  • Molecular Sensors and Ion Detection
  • Stress Responses and Cortisol
  • Enzyme Production and Characterization
  • Viral gastroenteritis research and epidemiology
  • Advanced biosensing and bioanalysis techniques
  • Bone Metabolism and Diseases
  • Genomics and Phylogenetic Studies

Consejo Nacional de Investigaciones Científicas y Técnicas
2011-2025

University of Buenos Aires
2008-2025

Fundación Ciencias Exactas y Naturales
2008-2024

Centro Científico Tecnológico - San Luis
2013-2024

National University of San Luis
2009-2024

University of Veterinary Medicine Hannover, Foundation
2019-2021

Albert Einstein College of Medicine
2019

Centro Científico Tecnológico - San Juan
2012

Planta Piloto de Ingeniería Química
2011

Alphaviruses and flaviviruses are important human pathogens that include Chikungunya virus (CHIKV), Dengue (DENV), Zika (ZIKV), which can cause diseases in humans ranging from arthralgia to hemorrhagic fevers microcephaly. It was previously shown treatment with surface layer (S-layer) protein, present on the bacterial cell-envelope of Lactobacillus acidophilus, is able inhibit viral infections by blocking pathogen's interaction DC-specific intercellular adhesion molecule 3-grabbing...

10.3389/fmicb.2019.00810 article EN cc-by Frontiers in Microbiology 2019-04-16

C-type lectin receptors (CLRs) are pattern recognition that crucial in the innate immune response. The gastrointestinal tract contributes significantly to maintenance of homeostasis; it is shelter for billions microorganisms including many genera Lactobacillus sp. Previously, was shown host-CLR interactions with gut microbiota play a role this context. Macrophage-inducible (Mincle) Syk-coupled CLR sensing mucosa-associated commensals. In study, we identified Mincle as receptor Surface...

10.3389/fimmu.2021.602067 article EN cc-by Frontiers in Immunology 2021-03-01

Lysinibacillus sphaericus strains belonging the antigenic group H5a5b produce spores with larvicidal activity against larvae of Culex mosquitoes. C7, a new isolated strain, which presents similar biochemical characteristics and Bin toxins in their as reference strain 2362, was, however, more active The contribution surface layer protein (S-layer) to this behaviour was envisaged since envelope has been implicated pathogenicity several bacilli, we had previously reported its association...

10.1371/journal.pone.0111114 article EN cc-by PLoS ONE 2014-10-29

ABSTRACT We describe a new enzymatic functionality for the surface layer (S-layer) of Lactobacillus acidophilus ATCC 4356, namely, an endopeptidase activity against cell wall Salmonella enterica serovar Newport, assayed via zymograms and identified by Western blotting. Based on amino acid sequence comparisons, hydrolase was predicted to be located at C terminus. Subsequent cloning expression C-terminal domain in Bacillus subtilis resulted functional verification activity.

10.1128/aem.01712-08 article EN Applied and Environmental Microbiology 2008-10-18

Folliculostellate cells (FSC) have been reported in pituitary of several mammalian species. FSC morphology and secreted sub- stances instrumental to the under- standing their function. The purpose this work was perform an immunohistochemi- cal, morphometric ultrastructural study pars distalis adult male viscacha analyze relation with hormone secreting cells. Immunohistoche- mistry image analysis were carried out different sectors gland, from middle (sector 1) glandular periphery 5)....

10.4081/ejh.2010.e1 article EN cc-by-nc European Journal of Histochemistry 2010-01-20

Polycystic ovarian syndrome is the most common endocrine disorder among women of reproductive age. Little known about its etiology, although evidence suggests an intrinsic abnormality in which endocrine, metabolic, neural and immune factors would be involved. In this work, effects macrophage (MO) secretion on apoptosis a polycystic ovary rat model (PCO rat) induced by estradiol valerate are studied. Spleen MO secretions were used to stimulate ovaries interstitial granulosa cells from both...

10.1530/rep-15-0216 article EN Reproduction 2015-08-12

ABSTRACT We present the 1,956,699-bp draft genome sequence of Lactobacillus acidophilus strain ATCC 4356. Comparative genomic analysis revealed 99.96% similarity with L. NCFM NC_006814.3 and 99.97% La-14 NC_021181.2 genomes.

10.1128/genomea.01421-14 article EN Genome Announcements 2015-01-16

Arsenic determination in natural waters is an issue of current research. This article reports a novel hydride generation (HG) approach developed for As with electrothermal atomic absorption spectrometry (ETAAS) detection. The HG process was interfaced ETAAS through trapping onto carbon nanotubes microcolumn. To this end homemade gas–liquid separator used, allowing arsine formation and its flow throughout the CNT retention involved thus solid phase extraction from gas to support. Once...

10.1039/c3ja30385c article EN Journal of Analytical Atomic Spectrometry 2013-01-01
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