A5067999103- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Escherichia coli research studies
- Antibiotic Use and Resistance
- Gut microbiota and health
- Microbial Community Ecology and Physiology
- Bacteriophages and microbial interactions
- Vibrio bacteria research studies
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Soil Carbon and Nitrogen Dynamics
- Urinary Tract Infections Management
- Infections and bacterial resistance
- Bee Products Chemical Analysis
National University of Ireland, Maynooth
2019-2024
Dublin City University
2020
Abstract Water quality testing does not recognise antimicrobial resistance (AMR) and is often limited to indicators of faecal contamination Escherichia coli Enterococcus species. In Europe, data on AMR in drinking water scarce. Ireland, as many countries, household supplied via mains or private wells schemes. Using citizen science, we identified Irish supplies reservoirs resistant bacteria (ARB). Gram-negative ( n = 464) Gram-positive 72) were isolated. We instances potentially opportunistic...
Wastewater treatment plants (WWTPs) provide optimal conditions for the maintenance and spread of antibiotic resistant bacteria (ARB) resistance genes (ARGs). In this work we describe occurrence faecal coliforms their mechanisms in effluent two urban WWTPs Ireland. This information is critical to identifying role dissemination ARB ARGs into environment. Effluent samples were collected from Spring Autumn 2015 2016. The bacterial susceptibility patterns 13 antibiotics determined. phenotypic...
Grasslands cover a large proportion of global agricultural landmass used to feed herbivores and ruminants link the environment food chain via animals onto humans. However, most scientific studies antimicrobial resistance microbiomes at environmental - animal nexus have focused on soil or vegetables rather than grasslands. Based previous microbiome phyllosphere-soil we hypothesised that resistomes across grass would core shared taxa genes (ARGs), but in addition each also minority unique...
The human gut microbiome includes beneficial, commensal and pathogenic bacteria that possess antimicrobial resistance (AMR) genes exchange these predominantly through conjugative plasmids. Escherichia coli is a significant component of the gastrointestinal typically non-pathogenic in this niche. In contrast, extra-intestinal E. (ExPEC) including ST131 may occupy other environments like urinary tract or bloodstream where they express enabling AMR host cell adhesion type 1 fimbriae. extent to...
Abstract Plasmids play a crucial role in the spread of antimicrobial resistance genes (ARGs) across One Health due to their ability transfer wide range ARGs within and bacterial species biomes. We sequenced 173 circularised plasmids transferred from wastewater treatment plant (WWTP) effluent into Escherichia coli subsequently characterised genetic content. Multiple multidrug resistant were identified with significant number mega (>100Kb). existing isolation rare almost all existed other...
Our study provides novel insights into the global nature of antimicrobial resistance (AMR) plasmids across food chain. We provide compelling evidence globetrotting AMR and need for surveillance to sequence with a template analyses others expand these data. The analysed were detected in 63 countries samples from humans, animals environment. They contained combination known genes, metal virulence factors, phage replicon types.
The human gut microbiome includes beneficial, commensal and pathogenic bacteria that possess antimicrobial resistance (AMR) genes exchange these predominantly through conjugative plasmids. Escherichia coli is a significant component of the gastrointestinal typically non-pathogenic in this niche. In contrast, extra-intestinal E. (ExPEC) including ST131 may occupy other environments like urinary tract or bloodstream where they express enabling AMR host adhesion type 1 fimbriae. extent to which...
Abstract The human gut microbiome includes beneficial, commensal and pathogenic bacteria that possess antimicrobial resistance (AMR) genes exchange these predominantly through conjugative plasmids. Escherichia coli is a significant component of the gastrointestinal typically non-pathogenic in this niche. In contrast, extra-intestinal E. (ExPEC) including ST131 may occupy other environments like urinary tract or bloodstream where they express enabling AMR host cell adhesion type 1 fimbriae....
Abstract Wastewater treatment plants (WWTPs) provide optimal conditions for the maintenance and spread of antibiotic resistant bacteria (ARB) resistance genes (ARGs). In this work we describe occurrence faecal coliforms their mechanisms in effluent two urban WWTPs Ireland. Effluent samples were collected from Spring Autumn 2015 2016. The bacterial susceptibility patterns to 13 antibiotics determined. phenotypic tests carried out identify AmpC or extended-spectrum β-lactamase (ESBL)...
Abstract Wastewater treatment plants (WWTPs) provide optimal conditions for the maintenance and spread of antibiotic resistant bacteria (ARB) resistance genes (ARGs). In this work we describe occurrence faecal coliforms their mechanisms in effluent two urban WWTPs Ireland. Effluent samples were collected from Spring Autumn 2015 2016. The bacterial susceptibility patterns to 13 antibiotics determined. phenotypic tests carried out identify AmpC or extended-spectrum β-lactamase (ESBL)...
Grasslands cover a large proportion of global agricultural landmass used to feed herbivores and ruminants link the environment food chain via animals onto humans. However, most scientific studies antimicrobial resistance microbiomes at environmental – animal nexus have focused on soil or vegetables rather than grasslands. Based previous microbiome phyllosphere-soil we hypothesised that resistomes across grass would core shared taxa genes (ARGs), but in addition each also minority unique...