Abstract The ability to monitor and quantify glutathione (GSH) in live cells is essential order gain a detailed understanding of GSH‐related pathological events. However, owing their irreversible response mechanisms, most existing fluorescent GSH probes are not suitable for this purpose. We have developed ratiometric probe (QG‐ 1 ) quantitatively monitoring cellular GSH. responds specifically reversibility with an ideal dissociation constant ( K d 2.59 m fast time t 1/2 =5.82 s). also...

Abstract Purely organic room-temperature phosphorescence has attracted attention for bioimaging but can be quenched in aqueous systems. Here we report a water-soluble ultralong phosphorescent supramolecular polymer by combining cucurbit[n]uril (CB[7], CB[8]) and hyaluronic acid (HA) as tumor-targeting ligand conjugated to 4-(4-bromophenyl)pyridin-1-ium bromide (BrBP) phosphor. The result shows that CB[7] mediated pseudorotaxane CB[7]/HA–BrBP changes from small spherical aggregates linear...

Abstract Constructing ultralong organic phosphorescent materials possessing a high quantum yield is challenging. Herein, assemblies of purely supramolecular pins composed alkyl‐bridged phenylpyridinium salts and cucurbit[8]uril (CB[8]) are reported. Different from “one host with two guests” “head‐to‐tail” binding, the binding formation one guest” “head‐to‐head,” which overcomes electrostatic repulsion promotes intramolecular charge transfer. The pin 1/CB[8] displays afterglow phosphorescence...

ConspectusHyaluronic acid (HA), which contains multiple carboxyl, hydroxyl, and acetylamino groups is an agent that targets tumors, has drawn great attention in supramolecular diagnosis treatment research. It can not only assemble directly with macrocyclic host–guest complexes through hydrogen bonding electrostatic interactions but also be modified compounds or functional guest molecules by amidation reaction used for further assembly. Macrocycles play a main role the construction of drug...

Abstract Macrocycle‐induced formation of pure organic supramolecular aggregates is a challenge that has attracted considerable attention from researchers in the fields chemistry, biology, and materials science. In particular, aggregation induced by water‐soluble cyclodextrins calixarenes, which are two classic macrocycles with hydrophobic cavity hydrophilic external surface, interest because these host molecules can form guest via various noncovalent interactions, including van der Waals...

A highly efficient light-harvesting system with two-step sequential energy transfer was designed by the nonconvalent interaction of pillar[5]arene pyridinium modified tetraphenylethene, sulforhodamine 101 and sulfonated aluminum phthalocyanine.

Abstract Herein, multilevel supramolecular assemblies are reported based on sulfobutylether‐β‐cyclodextrin (SBE‐βCD) and cucurbit[8]uril (CB[8]), which can control the topological morphology from nanoparticles to nanosheets modulate multicolor luminescence. Benefiting large cavity of CB[8] its strong binding affinity with positively charged tetraphenylethylene pyridinium (TPE‐Py), a 1:2 stoichiometric assembly is formed through host–guest interactions constants 2.95 × 10 11 M −2 fluorescence...

Multivalent supramolecular assemblies have recently attracted extensive attention in the applications of soft materials and cell imaging. Here, we report a novel multivalent assembly constructed from 4-(4-bromophenyl)pyridine-1-ium bromide modified hyaluronic acid (HABr), cucurbit[8]uril (CB[8]) laponite® clay (LP), which could emit purely organic room-temperature phosphorescence (RTP) with lifetime up to 4.79 ms aqueous solution via interactions. By doping dyes rhodamine B (RhB) or...

The construction of supramolecular assembly whose singlet oxygen (1O2) generation capability can be controllably regulated in water still remains challenging. Herein, a novel cyclodextrin secondary was fabricated from the photochromic-switch moiety diarylethene-bridged dicyclodextrin, adamantane-polypyridyl ruthenium photosensitizer, and cancer-cell-targeting ligand β-cyclodextrin-grafted hyaluronic acid, which not only possessed ability but also served as cell imaging photodynamic therapy...

Abstract The ability to monitor and quantify glutathione (GSH) in live cells is essential order gain a detailed understanding of GSH‐related pathological events. However, owing their irreversible response mechanisms, most existing fluorescent GSH probes are not suitable for this purpose. We have developed ratiometric probe (QG‐ 1 ) quantitatively monitoring cellular GSH. responds specifically reversibility with an ideal dissociation constant ( K d 2.59 m fast time t 1/2 =5.82 s). also...

Highly efficient light-harvesting amphiphilic supramolecular assemblies were reported for detecting sulfites in living cells, which showed obvious signal amplification, with an antenna effect of up to 28.1.

A unique fluorescent supramolecular assembly was constructed from coumarin-modified β-cyclodextrin and an adamantane-modified cyclic arginine–glycine–aspartate peptide for high-efficiency real-time monitoring of biothiols in cancer cells.

A porous intramolecular D–A integrated carbon nitride with boosted photocatalytic activity was constructed via thermal melting followed by copolymerization of m -aminophenol urea.

Abstract Cascade energy capturers based on supramolecular assembly have recently generated great research interest in the field of luminescent materials. Herein is reported a cucurbit[8]uril (CB[8])‐encapsulated coumarin‐bridged phenylpyridinium salt (G) to form biaxial polypseudorotaxane (G⊂CB[8]), which not only induces phosphorescence guest G, but also activates photodimerization coumarin functional group CB[8] cavity (G‐dimer⊂CB[8]) further boost its emission, extending lifetime from...

The mechanisms of ethanol synthesis from syngas including CHx (x = 1–3) species and C2 oxygenates on the stepped Rh(211) surface have been systematically investigated by using density functional theory together with a periodic slab model. Our results show that among all species, CH3 is most favorable monomer, which more than CH3OH formation; this result quite different flat Rh(111). Beginning + CHO → CH3CHO dominantly contributes to formation oxygenates; subsequently, successively...

The high-efficiency transition metal-free electrocatalytic nitrate reduction reaction (NO3–RR) for ammonia synthesis has received more attention because of its green and environmentally friendly characteristics. Here, we report an efficient electrochemical NH3 directly from purely organic macrocyclic compounds α-, β-, γ-cyclodextrins (CDs)-catalyzed electroreduction under ambient conditions. In comparison with β-CDs, parent γ-CD presented uncommon catalytic performance a relatively higher...

Abstract A purely organic supramolecular assembly emitting three‐photon room‐temperature phosphorescence (RTP) is constructed from a macrocyclic host, cucurbit[8]uril (CB[8]), and 4‐bromophenyl pyridine salt having an alkyl chain length of 6 or 12 carbon atoms ( 6C 12C , respectively). Benefiting host confined guests, the encapsulation in CB[8] cavity results absorption subsequent near‐infrared (NIR) emission. Notably, secondary with sulfonated β‐cyclodextrin (SCD) further enhances emission...

Abstract Molecular aggregation or supramolecular aggregation‐induced emission is one of the research hotspots in chemistry, biology, and materials. Herein, we report negatively charged sulfato‐β‐cyclodextrin (SCD) induced cyanovinylene derivatives (DPy‐6C) directional to form regular nanorods (DPy‐6C@SCD) through multivalent interactions, not only achieves ultraviolet‐visible absorption redshifted from 453 521 nm but also displays near‐infrared (NIR) with a large spectral redshift 135 nm....