A5067354257- Aortic Disease and Treatment Approaches
- Acute Lymphoblastic Leukemia research
- Cardiac Valve Diseases and Treatments
- Sperm and Testicular Function
- Congenital Heart Disease Studies
- Chronic Lymphocytic Leukemia Research
- Animal Diversity and Health Studies
- Reproductive Biology and Fertility
- Cardiac and Coronary Surgery Techniques
- Chronic Myeloid Leukemia Treatments
- Platelet Disorders and Treatments
- Sepsis Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Eosinophilic Disorders and Syndromes
- Infective Endocarditis Diagnosis and Management
- Maternal and Perinatal Health Interventions
- Radiomics and Machine Learning in Medical Imaging
- Sesame and Sesamin Research
- Vascular anomalies and interventions
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Brain Tumor Detection and Classification
- Neonatal and Maternal Infections
- Agriculture and Rural Development Research
- Bariatric Surgery and Outcomes
- Optical Imaging and Spectroscopy Techniques
Zagazig University
2008-2024
Hamad Medical Corporation
2024
University Hospital Bonn
2024
University of Toledo
2024
St. Jude Children's Research Hospital
2023-2024
Qatar University
2021-2024
Nottingham University Hospitals NHS Trust
2024
Islamic University of Madinah
2021
University of Florida
2017-2020
Ain Shams University
1998-2019
Abstract Vascular smooth muscle cells (VSMCs) play a critical role in regulating vasotone, and their phenotypic plasticity is key contributor to the pathogenesis of various vascular diseases. Two main VSMC phenotypes have been well described: contractile synthetic. Contractile VSMCs are typically found tunica media vessel wall, responsible for tone diameter. Synthetic VSMCs, on other hand, intima adventitia, involved repair remodeling. Switching between synthetic occurs response insults...
Although cure rates for childhood acute lymphoblastic leukemia (ALL) exceed 90%, ALL remains a leading cause of cancer death in children. Half relapses arise children initially classified with standard-risk (SR) disease.
Hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) patients has transitioned from the standard of care to a treatment option limited those with unsatisfactory tyrosine kinase inhibitor (TKI) responses and advanced disease stages. In recent years, threshold undergoing HSCT increased. Most CML now have life expectancies comparable general population, therefore, goal therapy is shifting toward achieving treatment-free remission (TFR). While TKI discontinuation...
Chimeric Antigen Receptor T-cell (CAR-T) therapy has emerged as a groundbreaking and highly promising approach for the management of cancer. This paper reviews efficacy CAR-T in treatment various hematological malignancies, also, with mention its effect on solid tumors, which they have not received FDA approval yet. Different common uncommon side effects are also discussed this paper, attention to each drug separately. By reviewing recommendations research, we extensively dose-limiting...
Purpose We conducted a comprehensive meta-analysis to compare the effects of balanced crystalloids (BC) and isotonic saline (IS) in pediatric sepsis.
Chronic myeloid leukemia (CML), while traditionally a disease of the elderly, has recently risen in incidence among younger patients. Hence, fertility concerns have emerged considering process and treatments, especially with current scarce conflicting recommendations. This review explores impact CML treatments including first-line tyrosine kinase inhibitors (TKIs) other on male chronic (CML) The aim this was to compile available evidence ultimately tailor treatment plans for patients whom...
The global practice of pain management during labor involves the use Epidural Analgesia (EA) or intramuscular (IM) morphine. However, impact these methods on maternal and neonatal short-term outcomes remains unclear. study evaluates exposure to EA IM morphine NICU admission rates explores other associated factors like sepsis, respiratory distress, instrumental delivery, birth traumas, low APGAR scores, chorioamnionitis. A at Women's Wellness Research Center in Qatar analyzed 7,721 low-risk...
Gorham-Scout disease (GSD) is a rare skeletal disorder of unknown etiology characterized by progressive osteolysis and excessive lymphovascular proliferation. Chylothorax life-threatening complication. A teenager presented with left pleural effusion on background chronic flank collection secondary to malformation. Cytology the fluid confirmed chylothorax rib excision biopsy GSD. The patient underwent thoracotomy, decortication, pleurectomy, which helped stabilize chylothorax; ongoing...
The present study was conducted on 1640 oocytes of camels to investigate the effect supplementing culture medium with epidermal growth factor (EGF) competence mature and develop in vitro using frozen semen season recovery rate quality recovered oocytes.Oocytes were collected during breeding (n=883) nonbreeding (n=757) seasons from she camels' ovaries (n=191) delivered normal saline solution at 37 o C a local slaughterhouse.Cumulus complexes (COCs) by slicing technique.Good-quality selected...
The current study was conducted to evaluate the effects of maturation time (30 or 40 hours) on rate (%) and two sources spermatozoa; epididymal spermatozoa (G1), frozen semen (G2) insemination methods IVF (G1 G2) intra-cytoplasmic sperm injection (ICSI) (G3) cleavage development competence in vitro produced embryos as a trial improve reproductive efficiency dromedary camel.Cumulus oocytes complexes (COCs) were recovered from ovaries by slicing technique.Based morphological characteristics...
Background: Valve performance and clinical outcomes after surgical AVR are thought to be affected by pre-existing comorbidities, such as chronic kidney disease (CKD), diabetes, metabolic syndrome. The IMPACT registry aims assess the durability hemodynamics of a novel bioprosthesis in real-world setting with focus on comorbidities.
Background: Minimally invasive aortic valve surgery via right anterior mini-thoracotomy (RAMT) access has been gaining popularity in cardiac surgery. This can be a good option relatively younger patients with longer life expectancy due to the lower morbidity profile addition esthetic advantages. The current study investigates clinical outcomes of under 50 years age who received minimally endoscopic assisted replacement RAMT.
Identifying key pathological features in brain MRIs is crucial for the long-term survival of glioma patients. However, manual segmentation time-consuming, requiring expert intervention and susceptible to human error. Therefore, significant research has been devoted developing machine learning methods that can accurately segment tumors 3D multimodal MRI scans. Despite their progress, state-of-the-art models are often limited by data they trained on, raising concerns about reliability when...
Background: In neonatal sepsis, the purpose of this study is to investigate possible diagnostic and prognostic utility receptor interacting protein 3 (RIP3). Methods: This case control included 70 participants divided into 2 groups, 35 sepsis cases controls. Plasma level Receptor Interacting Protein (RIP3) before after antibiotic treatment was assessed all subjected participants. Results: There highly statistical significant difference between two groups as regards RIP3 levels. Regarding...