A5039837062- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Magnolia and Illicium research
- Heavy Metal Exposure and Toxicity
- Wound Healing and Treatments
- Environmental Toxicology and Ecotoxicology
- Trace Elements in Health
- Phytochemistry and Biological Activities
- Heavy metals in environment
- Dermatology and Skin Diseases
- Toxin Mechanisms and Immunotoxins
- Phytochemical Studies and Bioactivities
- Herbal Medicine Research Studies
- Selenium in Biological Systems
- Macrophage Migration Inhibitory Factor
- Nanoparticles: synthesis and applications
- Dye analysis and toxicity
- Alkaloids: synthesis and pharmacology
- Genetic and Environmental Crop Studies
- Laser-Ablation Synthesis of Nanoparticles
- Plant Parasitism and Resistance
- Medicinal Plant Research
- Gut microbiota and health
University of Oradea
2020-2025
Liposomes continue to attract great interest due their increased bioavailability in the body and because substances encapsulated are protected while maintaining effectiveness. The aim of this study is obtain “giant” liposomes by lipid film hydration using a preparation formula with two different phospholipids, phosphatidylcholine (PC) phosphatidylserine (PS). Firstly, macro- microscopic characterization, total phenols content antioxidant capacity plant Stellaria media (L.) Vill. were...
The healing of skin wounds remains an important concern in medicine, especially chronic caused by various diseases such as diabetes. Using herbs or herbal products to heal is a therapeutic challenge for traditional medicine. In this context, the main aim our work was highlight vitro potential Stellaria media (L.) Vill. (SM) extract using scratch assay on normal human dermal fibroblasts (NHDF). ability stimulate cell migration and proliferation under influence different concentrations SM...
Periodontal disease and diabetes often co-occur; both are characterized by chronic inflammation. This study aimed to investigate the anti-inflammatory effects of carvacrol magnolol when incorporated into a periodontal hydrogel topically applied Wistar rats with diabetes-associated disease. Forty male albino were divided four groups: PD (induced periodontitis), PDC periodontitis treated carvacrol), PDM magnolol), PDCM magnolol). Post treatment, gingival tissue samples collected measure levels...
The Allium test is a cytological method used to monitor the impact of heavy metals. It can be evaluate meristematic tissues and highlight abnormalities occurring during mitotic division, with advantage being both rapid economical. Copper lead are among most widespread metals in everyday life, mainly due worldwide expansion industrialization, present soil, water, air. Using sativum as bioindicator for this study, statistical analysis confirmed significant differences genotoxicity between two...
Functional foods play a crucial role in contemporary dietary strategies. This study investigates the incorporation of oregano oil, bioactive extract that is known for its antimicrobial and antioxidant properties, into gelatin-based gummy jellies to develop functional food products with controlled release properties. The were evaluated mass uniformity, swelling index, disintegration time, tensile strength under simulated oral gastric conditions. results showed oil significantly reduced index...
Natural compounds are used in modern dermal treatments to avoid side effects commonly associated with conventional treatments. The aim of our study was develop a liposomal formulation including black mulberry extract and highlight its potential on the healing normal human fibroblasts (NHDF) vitro using scratch test. Mulberry-loaded liposomes (MnL) were prepared thin-film hydration method based cholesterol (C) phosphatidylcholine (PC) 1:3 (w/w) ratio. characterized by analyzing size, electric...
The status of parsley as a well-known folk medicine noted for its nutritional and medicinal properties prompted the exploration potential functional food natural remedy. paper aims to investigate enhance muscle function alleviate psoriasiform dermatitis, eventually establishing it natural, well-tolerated alternative with specific benefits both muscles skin. This study examines tolerability in cohort 937 participants by assessing immunoglobulin G (IgG) reactions. findings reveal high...
Applications of the Drosophila melanogaster (D.m.) research model have an important means both for genetic investigations and study metal toxicity, because D.m. has physiological mechanisms comparable to those in human organisms. In this research, toxic effect lead (Pb2+) copper (Cu2+) on four genotypes—the wild genotype (Oregon-R, used as control) three mutant genotypes (white, brown, white-vestigial)—was compared. Five replicates were made observe development progress monitorized exposed...
(1) The metabolic syndrome (MS) promotes acute and chronic infections, due to the pro-inflammatory condition given by TNFα IL6 or affecting microbiota. MS is also correlated with insulin resistance, causing inflammation infections throughout organism. (2) purpose of this study was track effect using essential oil Origanum vulgare L. (EOO) as an antibacterial treatment, compared allopathic treatment antibiotics in patients. A group 106 people divided into four subgroups: L1-staphylococcal...
Currently, the interest in synthesis of metallic nanoparticles has increased a lot because these systems are suitable to be used distinct fields such as medical, pharmaceutical, agricultural, environmental protection, etc. Their can done using different agents bacteria, fungi, and yeasts or plant extracts fresh plants. This paper aims synthesize silver (AgNPs) selenium (SeNPs) Stellaria media (L.) Vill (SM)
It is well recognized that oxidative stress contributes to chronic stress-induced cytotoxicity, which a major factor in the progression of many diseases, including periodontitis and diabetes. Formulas based on natural extracts with antioxidant properties are alternative treatment perspectives management such diseases. The aim our study was assess how carvacrol magnolol influence associated diabetes Wistar rats. Ninety rats were distributed nine groups: I—control group; II—diabetes group (D);...
There has been a significant increase in the use of botanical resources for formulation topical products designed medicinal and cosmetic applications. Sanguisorba minor Scop., species, exhibits variety properties potential applications field cosmetics. The aim this study was to formulate preparations, incorporating an extract derived from plant S. Scop. comprising combination roots, leaves, flowers. In initial phase, total seven combinations were prepared using extracts flowers (v/v/v)....
Drosophila melanogaster serves as a important research model both for genetic investigations and the study of metal toxicity, facilitating elucidation physiological mechanisms comparable to those human organisms. In our research, we evaluated toxicity effect resulting from exposure various concentrations lead copper on prolificity rates throughout life cycle (egg-adult) four genotypes melanogaster: wild-type (control), white, brown, white-vestigial. During study, were examined across three...
Mistletoe (Viscum album L.), a semi-parasitic medicinal plant, continues to be of interest, due its phytochemical composition. The leaves mistletoe contain phenols, which have variety biological effects. main goal was characterize the that parasitized Robinia pseudoacacia L., (called VAR) in terms phenolic compounds and assess wound healing potential vitro using scratch method. Furthermore, antioxidant capacity evaluated both by spectrophotometric techniques (DPPH, FRAP, TEAC), as well...
Nowadays, bacterial resistance to classical drugs (antibiotics) is increasingly mentioned in the literature. The same situation presented case of bacteria oral cavity, so there an acute need formulate new preparations with antibacterial or even anti-inflammatory antioxidant action. for these innovative has increased attention on plant compounds. Thus, this paper brings fore hydrogel-type formulations that are strongly compatible
COVID-19 is characterized by a strong inflammatory response leading to specific changes in the immune system cell counts. In this study, following biomarkers from laboratory data of patients have been analyzed: white blood cells (WBC), neutrophils, lymphocytes, monocytes, eosinophils, basophils, C-reactive protein, and glycemia. Various comparisons, correlations, ratios between these performed assess link pre-existing conditio
This study aimed to highlight the importance of phytochemical-based formulations in treatment wounds with different etiologies, avoiding possible side effects generated by conventional treatments. We present preparation method novel topical (cream, ointment, and hydrogel) based on mixed extracts Ocimum basilicum Tifolium pratense along evidence their antimicrobial antioxidant effect vitro. The anti-inflammatory wound healing properties