A5102821458- Parasitic infections in humans and animals
- Nigella sativa pharmacological applications
- Congenital Anomalies and Fetal Surgery
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Selenium in Biological Systems
- Toxoplasma gondii Research Studies
- Echinoderm biology and ecology
- Phytochemistry and biological activities of Ficus species
- Marine and coastal plant biology
- Parasite Biology and Host Interactions
- Paraquat toxicity studies and treatments
- Research on Leishmaniasis Studies
- Ophthalmology and Visual Health Research
- Urological Disorders and Treatments
- Insect Pest Control Strategies
- Parasitic Infections and Diagnostics
- Global Health and Epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Amoebic Infections and Treatments
- Berberine and alkaloids research
- Phytochemical and Pharmacological Studies
- Parasites and Host Interactions
- Medicinal Plants and Neuroprotection
- Hematological disorders and diagnostics
Lorestan University of Medical Sciences
2014-2020
Kerman University of Medical Sciences
2011-2017
Ahvaz Jundishapur University of Medical Sciences
2017
Lorestan University
2017
Bam University of Medical Sciences
2017
Université de Montréal
2016
Surgery remains the preferred treatment for hydatid cyst (cystic echinococcosis, CE). Various scolicidal agents have been used inactivation of protoscolices during surgery, but most them are associated with adverse side effects. The present study aimed to evaluate in vitro effect Nigella sativa (Ranunculaceae) essential oil and also its active principle, thymoquinone, against cysts. Protoscolices were aseptically aspirated from sheep livers having concentrations (0.01-10 mg/ml) thymoquinone...
Context: Leishmaniasis is a complex disease with broad spectrum of clinical presentations.
In this study, in vitro antidermatophytic activity against Trichophyton mentagrophytes , rubrum Microsporum canis and gypseum was studied by disk diffusion test assessment of minimum inhibitory concentration (MIC) using CLSI broth macrodilution method (M38-A2). Moreover, antileishmanial cytotoxicity B. vulgaris berberine promastigotes Leishmania major tropica were evaluated colorimetric MTT assay. The findings indicated that the various extracts particularly showed high potential pathogenic...
Zataria multiflora Boiss (Lamiaceae) commonly grows in Iran is a popular medicinal plant with various pharmacological activities mentioned traditional Iranian medicine and modern phytotherapy. This study was designed to evaluate the chemical composition scolicidal effects of Z. essential oil on protoscoleces hydatid cysts an vitro model. The components were identified by GC/MS analysis. Protoscoleces aseptically aspirated from livers naturally infected sheep. Various concentrations oil,...
Nowadays, surgery is considered as one of the most important treatments for hydatidosis. Due to laceration, cyst and spread content within it (protoscoleces) during that can put patient at risk re-infection, anaphylaxis shock even death, surgeons use some chemical drugs protoscolicidal agents. The study aimed evaluate scolicidal effects olive (
The aim of this study was to evaluate the antinociceptive effect biosynthetic copper nanoparticles from aqueous extract Capparis spinosa fruit.In study, green synthesis (CuNPs) performed using C. according method described previously. synthesized CuNPs were characterized UV-vis spectroscopy, Fourier transforms infrared (FTIR), scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX). evaluated by tail-flick, hot-plate, rotarod tests following oral administration mice with at...
In this investigation, the in vivo efficacy and safety of biogenic selenium nanoparticles (SeNPs) are assessed against acute toxoplasmosis caused by Toxoplasma gondii (Sarcocystidae) mice.Male NMRI mice were orally treated with normal saline (control group) SeNPs at doses 5 10 mg/kg once a day for 14 days. On 15th day, infected 104 tachyzoites T. RH strain intraperitoneal route. The mortality rate parasite load determined mice. mRNA levels IFN-γ, IL10, IL12, inducible nitric oxide synthase...
Background: The present work aimed to evaluate the chemical composition of Curcuma zadoaria essential oil and investigate its efficacy safety against hydatid cyst protoscoleces. Methods: Collected protoscoleces from liver fertile cysts infected sheep were exposed different concentrations (75, 150, 300 μl/mL) for 5-30 min in vitro ex vivo. Then, by using eosin exclusion assay, viability was studied. In next step, 24 male NMRI mice examined assess toxicity C. measuring biochemical...
Background: Studies showed that biogenic selenium nanoparticles (SeNPs) have a number of pharmacological properties, such as antimicrobial ones. Objective: The present investigation assesses the efficacy new patent against latent toxoplasmosis in mice model. Methods: Male BALB/c were orally treated with SeNPs at doses 2.5, 5, 10 mg/kg once day for 14 days. On 15th day, infected intraperitoneal inoculation 20-25 tissue cysts from Tehran strain Toxoplasma gondii. mean numbers brain and mRNA...
To date, herbal medicines are the important source in development of new drugs to remedy various diseases. However, it is crucial provide scientific justification these determine their side effects treatments. This study was aimed evaluate chemical composition, acute and subacute toxicity Satureja khuzestanica essential oil (SKEO) a mice model. Plant materials S. were collected from rural regions Lorestan Province, west Iran. Gas chromatography/mass spectrometry (GC/MS) analysis performed...
Abstract Background Omadacycline is an aminomethylcycline antibiotic in the tetracycline class that was approved by US FDA 2018 for treatment of community-acquired bacterial pneumonia and acute skin structure infections. It available both IV oral formulations. has broad-spectrum vitro activity clinical efficacy against infections caused Gram-positive Gram-negative pathogens. being evaluated a 3 month placebo-controlled Phase 2 trial omadacycline versus placebo adults with non-tuberculous...
To investigate the mechanisms leading to an increase in prevalence of blaCMY -2 conferring resistance ceftiofur pigs receiving a feed medicated with chlortetracycline and penicillin, examine effect supplementation clay mineral on this phenomenon.In 138 -positive Escherichia coli isolates from faeces supplemented or not 2% clinoptilolite, day 2 28 after weaning, two groups differed significantly respect their phylogenetic group: phylotype A predominated group, whereas phylotypes B1 D control...