A5041538333- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Neurogenetic and Muscular Disorders Research
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Child Nutrition and Feeding Issues
- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Central Venous Catheters and Hemodialysis
- Congenital Heart Disease Studies
- RNA modifications and cancer
- Cardiac Arrest and Resuscitation
- Cystic Fibrosis Research Advances
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Family and Patient Care in Intensive Care Units
- Dialysis and Renal Disease Management
- Energy Harvesting in Wireless Networks
- Congenital Diaphragmatic Hernia Studies
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
University of Manitoba
2024
University of Alberta
2017-2023
Women and Children’s Health Research Institute
2023
Stollery Children's Hospital
2022
University of Winnipeg
2021
Objectives To describe longitudinal trends in long-term non-invasive ventilation (NIV) use children including changes clinical characteristics, NIV technology, and outcomes. Methods This was a multicenter retrospective cohort of all started on from 2005 to 2014. All 0 18 years who used continuously for at least 3 months were included. Measures main outcomes were: 1) Number starting NIV; 2) primary medical condition; 3) complexity defined by number comorbidities, surgeries additional...
RATIONALE: Long-term noninvasive ventilation (NIV) is a standard therapy for children with impaired sleep breathing and chronic respiratory insufficiency. Evidence of longitudinal benefits, however, lacking.OBJECTIVES: The aim this study to determine the long-term NIV efficacy, its impact on growth changes in adherence complication rates over time.METHODS: This multicenter retrospective cohort examines started NIV, both continuous bi-level positive airway pressure, 10-year period. Data were...
Spinal muscular atrophy type 1 (SMA1) is a neuromuscular disorder with natural history of chronic respiratory failure and death during infancy without ventilation. Recently, disease-modifying therapies such as nusinersen have improved disease trajectory. However, objective data on the trajectory polysomnography outcomes, relationship between motor scores parameters, technology dependence healthcare utilization in children SMA1 remain to be elucidated.This was retrospective observational...
OBJECTIVE: The aim of this study is to compare the clinical characteristics, technology and outcomes between infants older children using long-term NIV.METHODS: In 10-year retrospective review, 120 were matched 240 in a 1:2 ratio based on sex closest date NIV initiation. Medical charts sleep laboratory records reviewed extract demographic, technology, polysomnography clinic outcome data.RESULTS: results demonstrate greater proportion cardiorespiratory disease [16% vs. 6%, OR 3.04 (95% CI...
Abstract Background Noninvasive ventilation (NIV) is a first‐line therapy for sleep‐related breathing disorders and chronic respiratory insufficiency. Evidence about predictors that may impact long‐term NIV outcomes, however, scarce. The aim of this study to determine demographic, clinical, technology‐related outcomes. Methods A 10‐year multicentred retrospective review children started on continuous or bilevel positive airway pressure (CPAP BPAP) in Alberta. Demographic, technology‐related,...
An increasing number of children with diverse medical conditions are using long-term noninvasive ventilation (NIV). This study examined the impact demographic, clinical, and technology-related factors on NIV adverse events in a large cohort NIV.This was multicenter retrospective review all who initiated province Alberta, Canada, from January 2005 to September 2014, followed until December 2015. Inclusion criteria were had used for 3 months or more at least one follow-up visit programs.We...
The aim of this study was to measure changes in adherence noninvasive ventilation (NIV) children during the first year COVID-19 pandemic.
Abstract Introduction Children with neuromuscular disease (NMD) typically develop progressive sleep disordered breathing (SDB), including obstructive apnea (OSA), nocturnal hypoxemia and/or hypoventilation, due to loss of upper airway muscle tone and weakness respiratory muscles. Commonly, the SDB initially presents during rapid eye movement (REM) sleep, as this stage is associated physiological atonia, but then progresses non-REM (NREM) ultimately daytime insufficiency. Non-invasive...
Background: Non-invasive ventilation (NIV) is a first-line therapy for sleep-related breathing disorders and chronic respiratory insufficiency. Evidence about predictors that may impact long-term NIV outcomes, however, scarce. The aim of this study to determine demographic, clinical, technology-related outcomes. Methods: A ten-year multi-centred retrospective review children started on continuous or bilevel positive airway pressure (CPAP, BPAP) in Alberta. Demographic, technology-related,...