A5019507256- Pancreatic function and diabetes
- Neural dynamics and brain function
- Pancreatic and Hepatic Oncology Research
- Neuroscience and Neuropharmacology Research
- Genetic and Kidney Cyst Diseases
- Visual perception and processing mechanisms
- Renal and related cancers
- Pancreatitis Pathology and Treatment
Indiana University – Purdue University Indianapolis
2024
Indiana University School of Medicine
2024
University of Chicago
2022
SUMMARY Pancreatic islet cells harbor primary cilia, small sensory organelles that detect environmental changes to regulate hormone secretion and intercellular communication. While the signaling capacity of cilia are well-appreciated, it is less recognized these also possess active motility, including in dense multicellular tissues such as pancreatic islet. In this manuscript, we use transgenic reporter mice an intravital imaging approach quantitate dynamics occurs live mouse islets. We...
Abstract Spike trains in cortical neuronal populations vary number and timing trial-to-trial, rendering a viable single trial coding scheme for sensory information elusive. Correlations between pairs of neocortical neurons can be segmented into either or noise according to their stimulus specificity. Here we show that spikes, corresponding reliable correlations imaged layer 2/3 mouse visual cortex are particularly informative stimuli. This set spikes is sparse exhibits comparable levels...