Mona M Elghareeb

ORCID: 0000-0003-4671-2196
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About
Contact & Profiles
Research Areas
  • Cholinesterase and Neurodegenerative Diseases
  • Pesticide Exposure and Toxicity
  • Parkinson's Disease Mechanisms and Treatments

Mansoura University
2025

Abstract This study investigates the neuroprotective effects of fucoxanthinol (FXL) against toxic activities two compounds known to induce neurotoxic in humans and animals. MPTP (1-methyl- 4-phenyl- 1,2,3,6-tetrahydropyridine) induces Parkinson’s disease (PD)-like phenotypes by inhibiting mitochondrial complex I dopaminergic neurons. Chlorpyrifos (CPF), another agent, is associated with acute long-term neurotoxicity primarily through acetylcholinesterase (AChE) inhibition. FXL demonstrated...

10.1007/s12031-025-02342-7 article EN cc-by Journal of Molecular Neuroscience 2025-04-08
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